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Development and validation of comprehensive nomograms from the SEER database for predicting early mortality in metastatic rectal cancer patients
BackgroundMetastatic rectal cancer is an incurable malignancy, which is prone to early mortality. We aimed to establish nomograms for predicting the...
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Predictors for temporary stomas non-closure among non-metastatic rectal cancer patients undergoing curative resection: a retrospective analysis
BackgroundThe primary treatment for non-metastatic rectal cancer is curative resection. However, sphincter-preserving surgery may lead to...
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Clinical significance of metastatic tumor deposit foci in rectal cancer in the lateral pelvic lymph node area
BackgroundAlthough previous studies have demonstrated that tumor deposits (TDs) are associated with worse prognosis in colon cancer, their clinical...
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Added value of spectral parameters in diagnosing metastatic lymph nodes of pT1-2 rectal cancer
PurposeTo investigate the added value of spectral parameters derived from dual-layer spectral detector CT (SDCT) in diagnosing metastatic lymph nodes...
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Pretreatment MRI-detected extramural venous invasion as a prognostic and predictive biomarker for neoadjuvant chemoradiotherapy in non-metastatic rectal cancer: a propensity score matched analysis
ObjectivesThis study evaluated pretreatment magnetic resonance imaging (MRI)–detected extramural venous invasion (pmrEMVI) as a predictor of survival...
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An isolated vaginal metastasis from rectal cancer: a case report
IntroductionVaginal metastasis from colorectal cancer is a rare occurrence, typically associated with other metastatic lesions. Isolated metastasis...
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Immunotherapy in rectal cancer patients—a propensity score matched analysis of the National Cancer Database
BackgroundRectal cancer patients with microsatellite instability (MSI-H) are candidates for immunotherapy. However, there is little evidence on its...
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An optimised liver-first strategy for synchronous metastatic rectal cancer leads to higher protocol completion and lower surgical morbidity
IntroductionThe optimal management of rectal cancer with synchronous liver metastases remains debatable. Thus, we propose an optimised liver-first...
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Modified neoadjuvant rectal score as a novel prognostic model for rectal cancer patients who underwent chemoradiotherapy
BackgroundThe neoadjuvant rectal score (NAR score) has recently been proposed as a better prognostic model than the conventional TNM classification...
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Rectal linitis plastica as the first presentation of metastatic lobular breast cancer: an endoscopic ultrasound diagnosis
Gastrointestinal tract is an uncommon site of breast cancer metastasis. Rectal linitis plastica (RLP) is a rare presentation of rectal neoplasia,...
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Elderly Rectal Cancer: An Updated Review
Purpose of ReviewTreatment of rectal cancer patients of advanced age should be modulated by life expectancy and tolerance. Due to the rapid advance...
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Primary adenocarcinoma arising from rectal implantation cyst after low anterior resection for rectal cancer 31 years previously
Rectal implantation cysts can occur at anastomotic sites after low anterior resection (LAR) for rectal cancer. Herein, we report a case of primary...
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Distinguishing mesorectal tumor deposits from metastatic lymph nodes by using diffusion-weighted and dynamic contrast-enhanced magnetic resonance imaging in rectal cancer
ObjectivesThis study aimed to identify whether apparent diffusion coefficient (ADC) values and dynamic contrast-enhanced magnetic resonance imaging...
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Mechanisms of metastatic colorectal cancer
Despite extensive research and improvements in understanding colorectal cancer (CRC), its metastatic form continues to pose a substantial challenge,...
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CACA guidelines for holistic integrative management of rectal cancer
PurposeColorectal cancer is a common malignant tumor worldwide. In China, the ratio of rectal cancer to colon cancer in terms of incidence is close...
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Treatment of hepatocellular carcinoma with a portal vein tumor thrombus and pulmonary metastases of rectal cancer with microsatellite stability using atezolizumab plus bevacizumab
Herein, we report the successful treatment using atezolizumab plus bevacizumab of a patient with hepatocellular carcinoma (HCC) with a portal vein...
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Development and validation of a nomogram to predict overall survival in young non-metastatic rectal cancer patients after curative resection: a population-based analysis
PurposeThis study aimed to establish and validate a nomogram for predicting overall survival (OS) in young non-metastatic rectal cancer (RC) patients...
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Prophylactic defunctioning stomas improve clinical outcomes of anastomotic leak following rectal cancer resections: An analysis of the US Rectal Cancer Consortium
PurposeAnastomotic leak (AL) is a complication of low anterior resection (LAR) that results in substantial morbidity. There is immense interest in...
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Surgical management of rectal cancer with synchronous treatment of prostate cancer
PurposeTo assess the safety and efficacy of synchronous treatments for rectal (RC) and prostate (PC) cancers.
MethodsSingle-center retrospective...
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Objective response after immune checkpoint inhibitors in a chemotherapy-refractory pMMR/MSS metastatic rectal cancer patient primed with experimental AlloStim® immunotherapy
BackgroundImmune Checkpoint Inhibitor (ICI) immunotherapy is most effective in immune effector cell infiltrated ‘hot’ tumor lesions, such as occurs...