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Metastatic Bone Disease An Integrated Approach to Patient Care
Skeletally related events make up approximately 20% of the cancer care economy. Advances in understanding the pathobiology and better biotargeted... -
Metabolic Bone Disease in Preterm Neonates With Fetal Growth Restriction (FGR): A Prospective Cohort Study
ObjectivesTo study the association of fetal growth restriction (FGR) with metabolic bone disease in preterm neonates.
MethodologyThis prospective...
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Effect of early preventive supplementation with calcium and phosphorus on metabolic bone disease in premature infants
ObjectiveThe objective was to study the effect of early preventive calcium and phosphorus supplementation on metabolic bone disease in preterm...
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Metabolic Bone Disease in Children With Transfusion-Dependent Thalassemia
ObjectiveThis study aimed to detect metabolic bone disease and endocrinopathies in a cohort of patients with transfusion-dependent thalassemia (TDT).
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Latent metabolic bone disease, skeletal dysplasia and other conditions related to low bone formation among 38 patients with subtrochanteric femoral fractures: a retrospective observational study
SummarySubtrochanteric femoral fracture is rare and intractable due to the possible association with low bone formation. Retrospective analysis of 38...
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Profile of metabolic bone disease in extremely low birth weight (ELBW) and very low birth weight (VLBW) neonates
BackgroundMetabolic bone disease (MBD) is an important cause of morbidity in premature, very low birth weight (VLBW), and sick infants and, if left...
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Misdiagnosed metabolic bone abnormality: a case report
BackgroundMetabolic bone disease causes significant morbidity and mortality, especially when misdiagnosed. With genetic testing, multiple disease...
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Role of fibroblast growth factor-23 as an early marker of metabolic bone disease of prematurity
PurposeMetabolic bone disease of prematurity (MBDP) remains a significant cause of morbidity in extremely premature newborns. In high-risk patients,...
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Metabolic bone disease of prematurity screening and individualized enteral mineral supplementation in high-risk neonates: a quality improvement initiative
ObjectivePrompted by an alarmingly low screening rate for metabolic bone disease of prematurity (MBDP), we aimed to increase MBDP screening with...
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Micro-scale vertebral features in postmenopausal women with alcohol-associated and metabolic-associated fatty liver disease: ex vivo bone quality analyses
PurposeAlthough epidemiological studies indicate increased fracture risk in women with alcohol-associated liver disease (AALD) and...
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Incidence of Metabolic Bone Disease After Implementation of Bone Protective Nutritional Strategies: A Prospective Cohort Study
BackgroundMetabolic bone disease (MBD) is a morbidity of multifactorial etiology with a high incidence in very preterm infants. We planned to study...
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Early elevated alkaline phosphatase as a surrogate biomarker of ongoing metabolic bone disease of prematurity
Very low birth weight (VLBW) neonates present a high risk of metabolic bone disease (MBD). Our main objective was to determine the easiest way to...
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Does metabolic control of the disease related with bone turnover markers in children with type 1 diabetes mellitus in Turkey?
BackgroundThe aim was to evaluate the effect of metabolic control on bone biomarkers in children with type I diabetes.
Materials and methods ... -
Metabolic abnormalities in the bone marrow cells of young offspring born to mothers with obesity
Background/ObjectivesIntrauterine metabolic reprogramming occurs in mothers with obesity during gestation, putting the offspring at high risk of...
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Obesity, diabetes and risk of bone fragility: How BMAT behavior is affected by metabolic disturbances and its influence on bone health
PurposeOsteoporosis is a metabolic bone disease characterized by decreased bone strength and mass, which predisposes patients to fractures and is...
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Association between fatty liver index and controlled attenuation parameters as markers of metabolic dysfunction-associated fatty liver disease and bone mineral density: observational and two-sample Mendelian randomization studies
SummaryPreviously observational studies did not draw a clear conclusion on the association between fatty liver diseases and bone mineral density...
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Serum cytokines and bone metabolic markers in patients with rheumatoid arthritis treated with biological disease modifying anti-rheumatic drugs
Introduction/objectives
Several biological disease-modifying anti-rheumatic drugs (bDMARDs) have been widely used for the management of rheumatoid...
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Craniosynostosis in primary metabolic bone disorders: a single-institution experience
PurposeThe incidence of metabolic bone diseases in pediatric neurosurgical patients is rare. We examined our institutional experience of metabolic...
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Amino Acid Metabolism in Bone Metastatic Disease
Purpose of ReviewBreast and prostate tumors frequently metastasize to the bone, but the underlying mechanisms for osteotropism remain elusive. An...