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Improving Chronic Venous Disease Management with Micronised Purified Flavonoid Fraction: New Evidence from Clinical Trials to Real Life
Chronic venous disease (CVD) develops in the microvessels, and is perpetuated by a vicious cycle of inflammation and endothelial activation,...
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VEIN STEP: A Prospective, Observational, International Study to Assess Effectiveness of Conservative Treatments in Chronic Venous Disease
IntroductionVEIN STEP was conducted to collect international data on the management of chronic venous disease (CVD) and to assess the effectiveness...
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New Perspectives on Micronised Purified Flavonoid Fraction in Chronic Venous Disease: From Microvalves to Clinical Effectiveness
The importance of chronic venous disease (CVD), as a cause of reduced quality of life and increased costs to healthcare systems, is expected to rise...
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Hemorrhoidal disease among doctors from grade-A tertiary hospitals in big cities of China: results from web-based doctors as patients survey
BackgroundDoctors are at high risk of develo** hemorrhoidal disease (HD), but it is unclear whether doctors are aware of this risk. The OASIS...
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Cardiovascular Insights for the Appropriate Management of Chronic Venous Disease: A Narrative Review of Implications for the Use of Venoactive Drugs
Evidence suggests that chronic venous disease (CVD) may be a cardiovascular disorder, as patients with CVD are prone to develo** arterial...
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The Benefits of Micronized Purified Flavonoid Fraction (MPFF) Throughout the Progression of Chronic Venous Disease
At the 2019 European Venous Forum in Zurich Switzerland, a symposium entitled “State of the art: benefits of MPFF throughout CVD progression” was...
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Clinical Efficacy of Conservative Treatment with Micronized Purified Flavonoid Fraction in Female Patients with Pelvic Congestion Syndrome
IntroductionPelvic congestion syndrome (PCS) may be effectively managed with conservative treatment in certain patients. Treatment with venoactive...
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Micronized Purified Flavonoid Fraction (MPFF) for Patients Suffering from Chronic Venous Disease: A Review of New Evidence
Chronic venous disease (CVD) is both prevalent and unavoidable in many people as a result of persistent or unalterable risk factors, the most...
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Micronized Purified Flavonoid Fraction in Hemorrhoid Disease: A Systematic Review and Meta-Analysis
IntroductionHemorrhoidal disease (HD) is a common and recurrent problem for many adults worldwide. Venoactive drugs, such as micronized purified...
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Optimising Decision Making in Chronic Venous Disease Management with Micronised Purified Flavonoid Fraction
Evidence-based medicine favours randomised controlled trials to limit bias and establish the effects of a treatment with statistical rigour. However,...
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Quality of Life in Chronic Venous Disease: Bridging the Gap Between Patients and Physicians
Chronic venous disease (CVD) has a negative impact on patients’ quality of life (QoL). This was demonstrated in the recent Patient Journey on CVD...
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Recurrence Rates and Pharmacological Treatment for Hemorrhoidal Disease: A Systematic Review
IntroductionHemorrhoidal disease (HD) is characterized by prolapse of the inflamed and bleeding vascular tissues of the anal canal. Although HD is...
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The Most Severe Stage of Chronic Venous Disease: An Update on the Management of Patients with Venous Leg Ulcers
Venous leg ulcers (VLUs) are the most severe manifestation of chronic venous disease (CVD). Due to their chronic nature, high recurrence rate and...
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Early Stages of Chronic Venous Disease: Medical Treatment Alone or in Addition to Endovenous Treatments
Chronic venous disease (CVD) is one of the most prevalent diseases worldwide. The health condition of most patients with early stage CVD will worsen...
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Advanced Stages of Chronic Venous Disease: Evolution of Surgical Techniques and Advantages of Associated Medical Treatment
Contemporary interventional treatment of primary chronic venous disease (CVD) is mainly focused on the treatment of venous reflux. The long-term...
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Ulcus cruris venosum
Venous leg ulcers develop in the course of advanced chronic venous insufficiency and represent the leading cause for chronic ulcerations of the lower...
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Efficacy of Micronized Purified Flavonoid Fraction-Based Venoactive Therapy After Endovenous Mechanochemical Obliteration: Prospective Comparative Study
BackgroundEndovenous interventions and minimally invasive open procedures are effective in the management of varicose veins, but can result in...
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Varikosis – aktuelle Therapiekonzepte
Varicosis is a chronic progressive disease characterized by varicose veins of the lower extremities. Pain, swelling and heaviness of the legs are...
