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Expression and diagnostic value of lncRNA MALAT1 and NLRP3 in lower limb atherosclerosis in diabetes
ObjectiveThis study aimed to examine the diagnostic predictive value of long non-coding RNA (lncRNA) metastasis-associated lung adenocarcinoma...
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DKK3 expression is associated with immunosuppression and poor prognosis in glioblastoma, in contrast to lower-grade gliomas
PurposeWe previously reported that expression of dickkopf-3 (DKK3), which is involved in the Wnt/β-catenin pathway, is significantly associated with...
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GATA3 expression in clear cell adenocarcinoma of the lower urinary tract: a potential diagnostic pitfall
BackgroundClear cell adenocarcinoma of the lower urinary tract (CCACLUT) is a rare primary malignant neoplasm with heterogenous morphology. There is...
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Tissue S100/calgranulin expression and blood neutrophil-to-lymphocyte ratio (NLR) in dogs with lower urinary tract urothelial carcinoma
BackgroundUrothelial carcinoma (UC) is the most common neoplasm of the canine lower urinary tract, affecting approximately 2% of dogs. Elderly female...
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Lower Levels of TET2 Gene Expression, with a Higher Level of TET2 Promoter Methylation in Patients with AML; Evidence for the Role of Aberrant Methylation in AML Pathogenesis
DNA methylation is a key epigenetic mechanism that is dysregulated in leukemia and plays a significant role in leukemogenesis. Ten-eleven...
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A gene expression profile for the lower osteogenic potent of bone-derived MSCs from osteoporosis with T2DM and the potential mechanism
BackgroundOsteoporosis (OP) patients complicated with type II diabetes mellitus (T2DM) has a higher fracture risk than the non-diabetic patients, and...
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A nomogram strategy for identifying the subclassification of IDH mutation and ATRX expression loss in lower-grade gliomas
ObjectivesTo construct a radiomics nomogram based on multiparametric MRI data for predicting isocitrate dehydrogenase 1 mutation (IDH +) and loss of...
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Lower gestational age is associated with lower cortical volume and cognitive and educational performance in adolescence
BackgroundGestational age (GA) is associated with later cognition and behavior. However, it is unclear how specific cognitive domains and brain...
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Association between the expression of epithelial–mesenchymal transition (EMT)-related markers and oncologic outcomes of colorectal cancer
BackgroundEpithelial–mesenchymal transition (EMT) is a key step in the development of colorectal cancer (CRC) that confers metastatic capabilities to...
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The expression of carcinoembryonic antigen mRNA in the lavage of the dissected area of the lateral lymph nodes influences the lateral recurrence of lower rectal cancer
PurposeTo determine whether or not migrating cancer cells are present on the surgical plane after lateral lymph node dissection (LLND) for lower...
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Modelling human lower urinary tract malformations in zebrafish
Advances in molecular biology are improving our understanding of the genetic causes underlying human congenital lower urinary tract (i.e., bladder...
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Insights into the associative role of hypertension and angiotensin II receptor in lower urinary tract dysfunction
In men, the lower urinary tract comprises the urinary bladder, urethra, and prostate, and its primary functions include urine storage and voiding....
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Dermatologic Conditions in Persons with Lower Limb Amputations: a Review
Purpose of ReviewThe goal of our paper was to examine literature and innovations made regarding dermatologic conditions in patients with lower limb...
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Population-Specific gene expression profiles in prostate cancer: insights from Weighted Gene Co-expression Network Analysis (WGCNA)
This study investigates the genetic factors contributing to the disparity in prostate cancer incidence and progression among African American men...
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STK3 higher expression association with clinical characteristics in intrinsic subtypes of breast cancer invasive ductal carcinoma patients
PurposeSTK3 has a central role in maintaining cell homeostasis, proliferation, growth, and apoptosis. Previously, we investigated the functional link...
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Fetal hemoglobin level predicts lower-risk myelodysplastic syndrome
The relationship between fetal hemoglobin (HbF) levels and disease prognosis in patients with myelodysplastic syndrome (MDS) is unclear. This study...
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Gene expression of adipokines and adipokine receptors in the tumor microenvironment: associations of lower expression with more aggressive breast tumor features
PurposeLimited epidemiologic data are available on the expression of adipokines leptin (LEP) and adiponectin (ADIPOQ) and adipokine receptors (LEPR,...
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Effect of TSH on aromatase expression of ovarian granulosa cells in obese mice
PurposeAromatase plays an important role in ovarian development, the normal progress of the menstrual cycle, and fertility status. Elevated aromatase...
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Assessment of TROP2, CEACAM5 and DLL3 in metastatic prostate cancer: Expression landscape and molecular correlates
Therapeutic approaches targeting proteins on the surface of cancer cells have emerged as an important strategy for precision oncology. To capitalize...
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Predictive capacity for local disease control of neogenin-1 (NEO1) transcriptional expression in patients with head and neck squamous cell carcinoma
PurposeTo analyze the predictive capacity for local disease control of the transcriptional expression of neogenin-1 (NEO1) gene in patients with head...
