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Molecular features and prognostic factors of locally advanced microsatellite instability-high gastric cancer
BackgroundMicrosatellite instability-high (MSI-H) tumors are distinct molecular subtypes in gastric cancer. However, a few studies have...
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Adjuvant treatment for locally advanced gastric cancer: an Asian perspective
Standard adjuvant treatment for locally advanced gastric cancer (LAGC) is regionally different. Whereas perioperative chemotherapy is the standard in...
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Computed tomography-based radiomics nomogram for predicting therapeutic response to neoadjuvant chemotherapy in locally advanced gastric cancer
Background and ObjectiveNeoadjuvant chemotherapy results in various responses when used to treat locally advanced gastric cancer, we aimed to develop...
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Analysis of influencing factors of nerve invasion in locally advanced gastric cancer
ObjectivesAccurate preoperative diagnosis of locally advanced gastric cancer (GC) with nerve invasion is very important for guiding the clinical...
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Digital histopathological images of biopsy predict response to neoadjuvant chemotherapy for locally advanced gastric cancer
BackgroundNeoadjuvant chemotherapy (NAC) has been recognized as an effective therapeutic option for locally advanced gastric cancer as it is expected...
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What determines complications and prognosis among patients subject to multivisceral resections for locally advanced gastric cancer?
BackgroundLocally advanced gastric cancer (GC) extending to the surrounding tissues may require a multivisceral resection (MVR) to provide the best...
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Deep learning nomogram for predicting neoadjuvant chemotherapy response in locally advanced gastric cancer patients
PurposeDeveloped and validated a deep learning radiomics nomogram using multi-phase contrast-enhanced computed tomography (CECT) images to predict...
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Minimally invasive elective gastrectomy after preoperative chemotherapy in a patient with frailty who presented with locally far advanced-stage gastric cancer: a case report
BackgroundHerein, we report a case of gastric antrum cancer with multiple invasions to other organs that was completely cured with laparoscopic...
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Impact of D2 Gastrectomy for Locally Advanced Gastric Cancer in the Era of Effective Adjuvant Chemotherapy
BackgroundGastrectomy with D2 dissection has been established as the standard procedure for locally advanced gastric cancer in the era of surgery...
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Predicting Peritoneal Carcinomatosis in Locally Advanced Gastric Cancer: The Significance of Tumor Markers in the Peritoneal Washing
PurposeGastric cancer is the fifth most common malignant tumor worldwide. Many attempts have been made over the years to investigate the relationship...
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Survival Benefit of Induction Chemotherapy with Paclitaxel and Carboplatin Followed by Chemoradiation Versus Postoperative Treatment in Locally Advanced Gastric Cancer: A Retrospective Cohort Study
BackgroundGastric cancer remains a prevalent worldwide illness that lacks a definitive cure. Recently, induction chemotherapy followed by concurrent...
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Current neoadjuvant therapy for operable locally advanced esophageal cancer
Locally advanced esophageal cancer has a poor prognosis, while an increasing number of patients are diagnosed with that. Neoadjuvant therapy has...
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Trastuzumab deruxtecan in patients with locally advanced or metastatic HER2-positive gastric cancer: a multicenter, open-label, expanded-access study
BackgroundTrastuzumab deruxtecan (T-DXd) is an antibody–drug conjugate that consists of an anti-human epidermal growth factor receptor 2 (HER2)...
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Spectral CT vs. diffusion-weighted imaging for the quantitative prediction of pathologic response to neoadjuvant chemotherapy in locally advanced gastric cancer
ObjectivesTo compare the performance of spectral CT and diffusion-weighted imaging (DWI) for predicting pathologic response after neoadjuvant...
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SOX combined with sintilimab versus SOX alone in the perioperative management of locally advanced gastric cancer: a propensity score–matched analysis
ObjectivesTo evaluate the efficacy of SOX combined with a programmed cell death protein-1 (PD-1) inhibitor compared with SOX alone in the...
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Perioperative chemotherapy versus adjuvant chemotherapy treatment for resectable locally advanced gastric cancer: a retrospective cohort study
BackgroundNeoadjuvant chemotherapy (NAC) is increasingly used in locally advanced gastric cancer (LAGC), but the clinical safety and efficacy are...
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Perioperative TAS-118 plus oxaliplatin in patients with locally advanced gastric cancer: APOLLO-11 study
BackgroundWe investigated the feasibility of perioperative chemotherapy with S-1 and leucovorin (TAS-118) plus oxaliplatin in patients with locally...
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Laparoscopic and open gastrectomy for locally advanced gastric cancer: a retrospective analysis in Colombia
IntroductionRadical gastrectomy has traditionally been the pillar treatment with curative intent for malignant tumors of the stomach. The safety of...
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Impact of chemotherapy delay on long-term prognosis of laparoscopic radical surgery for locally advanced gastric cancer: a pooled analysis of four randomized controlled trials
BackgroundAdjuvant chemotherapy following curative surgery for locally advanced gastric cancer (AGC) significantly improves long-term patient...
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Impact of 18FFDG-PET/CT and Laparoscopy in Staging of Locally Advanced Gastric Cancer: A Cost Analysis in the Prospective Multicenter PLASTIC-Study
BackgroundUnnecessary D2-gastrectomy and associated costs can be prevented after detecting non-curable gastric cancer, but impact of staging on...
