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The angiopoietin-like protein 4, apolipoprotein C3, and lipoprotein lipase axis is disrupted in patients with rheumatoid arthritis
BackgroundModulators of triglyceride metabolism include lipoprotein lipase (LPL), angiopoietin-like protein 4 (ANGPTL4), and apolipoprotein C-3...
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Rare novel
LPL mutations are associated with neonatal onset lipoprotein lipase (LPL) deficiency in two casesBackgroundLipoprotein lipase (LPL) deficiency is a monogenic lipid metabolism disorder biochemically characterized by hypertriglyceridemia (HTG)...
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Role of apolipoprotein C1 in lipoprotein metabolism, atherosclerosis and diabetes: a systematic review
Apolipoprotein C1 (apoC1) is a small size apolipoprotein whose exact role is not totally clarified but which seems to modulate significantly the...
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Is lysosomal acid lipase activity associated with the presence and severity of coronary artery disease?
BackgroundLipid metabolism is considerably complex and there can be many critical steps in atherogenesis. The association between lysosomal acid...
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Lipoprotein Lipase Deficiency
ObjectivesTo analyse the clinical and molecular spectrum of Lipoprotein Lipase (LPL) deficiency and to highlight the effect of a cost-effective...
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Lipoprotein glomerulopathy with markedly increased arterial stiffness successfully treated with a combination of fenofibrate and losartan: a case report
BackgroundLipoprotein glomerulopathy (LPG) is a apolipoprotein E (ApoE)-related glomerular disease and has been associated with type III...
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New Strategies for Lowering Low-Density Lipoprotein Cholesterol for Cardiovascular Disease Prevention
Purpose of ReviewThe primary and secondary prevention of atherosclerotic cardiovascular disease (ASCVD) relies on optimizing cardiovascular health...
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Genetic and Mechanistic Insights into the Modulation of Circulating Lipoprotein (a) Concentration by Apolipoprotein E Isoforms
Purpose of ReviewLipoprotein (a) [Lp(a)] is a highly atherogenic lipoprotein species. A unique feature of Lp(a) is the strong genetic determination...
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Increased high-density lipoprotein cholesterol in patients with type 2 diabetes and its correlates: a cross-sectional, matched case–control survey
BackgroundSo far, high-density lipoprotein cholesterol (HDL-C) levels and mortality were shown to have a U-shaped relationship. Additionally, high...
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The role of remnant cholesterol beyond low-density lipoprotein cholesterol in diabetes mellitus
BackgroundPrevious research has linked elevated low-density lipoprotein cholesterol (LDL-C) and remnant cholesterol (RC) with diabetes mellitus (DM)....
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A nonlinear relationship between the triglycerides to high-density lipoprotein cholesterol ratio and stroke risk: an analysis based on data from the China Health and Retirement Longitudinal Study
ObjectiveThe connection between triglycerides to high-density lipoprotein cholesterol (TG/HDL-C) ratio and stroke risk is controversial. Our goal was...
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High-Density Lipoprotein Cholesterol in Atherosclerotic Cardiovascular Disease Risk Assessment: Exploring and Explaining the “U”-Shaped Curve
Purpose of ReviewReview updates for the association of HDL-cholesterol with atherosclerotic cardiovascular disease (ASCVD) and discuss the approach...
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A case of tamoxifen-induced hypertriglyceridemia monitoring the changes in lipoprotein fractions over time
BackgroundTamoxifen, which is one of the selective estrogen receptor modulators (SERMs), can bring out life-threatening complication, e.g....
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Association of triglycerides to high-density lipoprotein cholesterol ratio with incident cardiovascular disease but not end-stage kidney disease among patients with biopsy-proven diabetic nephropathy
Increased triglycerides (TG) and decreased high-density lipoprotein cholesterol (HDL-C) are dyslipidemias characteristic of diabetes. Here, we aimed...
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MicroRNAs and Circular RNAs in Lipoprotein Metabolism
Purpose of ReviewNon-coding RNAs (ncRNAs) including microRNAs (miRNAs) and circular RNAs (circRNAs) are pivotal regulators of mRNA and protein...
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Serum levels of lipoprotein-associated phospholipase A2 are associated with coronary atherosclerotic plaque progression in diabetic and non-diabetic patients
BackgroundLp-PLA2 is linked to cardiovascular diseases and poor outcomes, especially in diabetes, as it functions as a pro-inflammatory and oxidative...
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Long-term visit-to-visit variability in low-density lipoprotein cholesterol is associated with poor cardiovascular and kidney outcomes in patients with primary nephrotic syndrome
PurposeIt is unclear whether long-term variability in low-density lipoprotein cholesterol (LDL-C) is associated with clinical outcomes in patients...
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The Role of High-Density Lipoprotein Cholesterol in 2022
Purpose of the ReviewHigh-density lipoproteins (HDL) are responsible for the transport in plasma of a large fraction of circulating lipids, in part...
