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Ovarian aging: energy metabolism of oocytes
In women who are getting older, the quantity and quality of their follicles or oocytes and decline. This is characterized by decreased ovarian...
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Role of anatomical location, cellular phenotype and perfusion of adipose tissue in intermediary metabolism: A narrative review
It is well-established that adipose tissue accumulation is associated with insulin resistance through multiple mechanisms. One major metabolic link...
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GATA6 inhibits the biological function of non-small cell lung cancer by modulating glucose metabolism
PurposeThis study aims to explore the role of GATA6 in lung cancer, with a focus on its impact on metabolic processes.
MethodsWe assessed GATA6...
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Machine-learning developed an iron, copper, and sulfur-metabolism associated signature predicts lung adenocarcinoma prognosis and therapy response
BackgroundPrevious studies have largely neglected the role of sulfur metabolism in LUAD, and no study has combine iron, copper, and sulfur-metabolism...
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Immune Metabolism in TH2 Responses: New Opportunities to Improve Allergy Treatment — Disease-Specific Findings (Part 1)
Purpose of ReviewRecent high-level publications have shown an intricate connection between immune effector function and the metabolic state of the...
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Enhanced tryptophan-kynurenine metabolism via indoleamine 2,3-dioxygenase 1 induction in dermatomyositis
ObjectivesExtrahepatic tryptophan (Trp)-kynurenine (Kyn) metabolism via indoleamine 2,3-dioxygenase 1 (IDO1) induction was found to be associated...
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Impact of leptin or melatonin on Sema4D overexpression-related bone metabolism
PurposeThe current study aims to investigate the regulatory impact of leptin or melatonin on bone metabolism as well as the underlying mechanism in...
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The impact of different levels of wheat diets on hepatic oxidative stress, immune response, and lipid metabolism in Tibetan sheep (Ovis aries)
BackgroundCompared with corn, wheat contains higher crude protein, amino acids concentration. However, wheat contains a mass of anti-nutritional...
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Divergent impacts on the gut microbiome and host metabolism induced by traditional Chinese Medicine with Cold or Hot properties in mice
BackgroundTraditional Chinese Medicine (TCM) has been practiced and developed in China over thousands of years under the guidance of a series of...
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Biochemical testing for inborn errors of metabolism: experience from a large tertiary neonatal centre
Inborn errors of metabolism are an individually rare but collectively significant cause of mortality and morbidity in the neonatal period. They are...
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Histone N-terminal acetyltransferase NAA40 links one-carbon metabolism to chemoresistance
Aberrant function of epigenetic modifiers plays an important role not only in the progression of cancer but also the development of drug resistance....
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Advances in Glycolysis Metabolism of Atherosclerosis
Glycolysis is an important way for various cells such as vascular wall endothelial cells, smooth muscle cells, macrophages, and other cells to obtain...
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Insight into pathogenomics and phylogeography of hypervirulent and highly-lethal Mycobacterium tuberculosis strain cluster
Background. The Mycobacterium tuberculosis Bei**g genotype is globally spread lineage with important medical properties that however vary among its...
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Dysfunctional lactate metabolism in human alveolar type II cells from idiopathic pulmonary fibrosis lung explant tissue
BackgroundIdiopathic Pulmonary Fibrosis (IPF) is the most common and progressive form of the interstitial lung diseases, leading most patients to...
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Inborn Errors of Metabolism—Approach to Diagnosis and Management in Neonates
Inborn errors of metabolism (IEM), otherwise known as inherited metabolic disorders (IMD), are individually rare, but collectively common. IEM pose a...
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Correlation of negative emotion, fatigue level and internet addiction in college students: implication for co** strategies
BackgroundInternet addiction has an important influence on the development of physical and mental health of college students. The purpose of this...
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The Role of Pi, Glutamine and the Essential Amino Acids in Modulating the Metabolism in Diabetes and Cancer
PurposeRe-examine the current metabolic models.
MethodsReview of literature and gene networks.
ResultsInsulin activates Pi uptake, glutamine...
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Role of fermented dairy products in the health benefits of a mediterranean diet
Mediterranean diet includes fermented dairy products like yogurt and cheese. These foods provide calcium, phosphorus, fat, carbohydrates and protein,...
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Methionine metabolism in chronic liver diseases: an update on molecular mechanism and therapeutic implication
As one of the bicyclic metabolic pathways of one-carbon metabolism, methionine metabolism is the pivot linking the folate cycle to the...
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Type 2 diabetes and succinate: unmasking an age-old molecule
Beyond their conventional roles in intracellular energy production, some traditional metabolites also function as extracellular messengers that...
