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1. Tumor-derived interleukin 35 mediates the dissemination of gemcitabine resistance in pancreatic adenocarcinoma

   Rapid development of drug resistance after chemotherapy is a major cause of treatment failure in individuals with pancreatic ductal adenocarcinoma...

   Huizhi Sun, Yi Ge, ... Chongbiao Huang in Oncogene

   Article 20 January 2024
   

2. Elevated expression of interleukin-27, IL-35, and decreased IL-12 in patients with thyroid-associated ophthalmopathy

   Purpose

   Thyroid-associated ophthalmopathy (TAO) is a chronic autoimmune disease. The interleukin-12 (IL-12) family includes IL-12, IL-23, IL-27, and...

   Pengbo Zhang, **bo Zhang, ... Huang Zhu in Graefe's Archive for Clinical and Experimental Ophthalmology

   Article 12 November 2022
   

3. CD19⁺CD24^highCD27⁺ B cell and interleukin 35 as potential biomarkers of disease activity in systemic lupus erythematosus patients

   Background

   Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that associates with aberrant activation of B lymphocytes and excessive...

   Hui **ong, Zengqi Tang, ... Qing Guo in Advances in Rheumatology

   Article Open access 09 December 2022
   

4. Elucidating the role of T-Reg related cytokines: serum transforming growth factor beta and interleukin-35 in alopecia areata

   Previous studies demonstrated that Th1 cytokines like IL-2, IL-12 and IFN-γ have initiatory role in alopecia areata (AA) and positive correlation...

   Tugcan Yuksek, Muzeyyen Gonul, ... Semra Isikoglu Hatil in Archives of Dermatological Research

   Article 24 May 2024
   

5. Interleukin-35 promotes Breg expansion and interleukin-10 production in CD19⁺ B cells in patients with ankylosing spondylitis

   Objective

   IL-35 is a potent immunosuppressive and anti-inflammatory cytokine, consisting of a p35 subunit and an Epstein–Barr virus–induced gene 3...

   Yu Zhang, Sixi Wei, ... Li Ma in Clinical Rheumatology

   Article Open access 14 April 2022
   

6. Interleukin-35 Mitigates ox-LDL-Induced Proatherogenic Effects via Modulating miRNAs Associated with Coronary Artery Disease (CAD)

   Purpose

   Recent emergence of miRNAs as important regulators of processes involving lesion formation and regression has highlighted miRNAs as potent...

   Shipra Bhansali, Amit Kumar Yadav, ... Veena Dhawan in Cardiovascular Drugs and Therapy

   Article 18 April 2022
   

7. Different expression levels of interleukin-35 in asthma phenotypes

   Background

   Interleukin (IL)-35 is a newly discovered inhibitory cytokine which is produced by regulatory B and T lymphocytes and belongs to the IL-12...

   Wei Li, Ruihan Gao, ... Peng Gao in Respiratory Research

   Article Open access 16 April 2020
   

8. Interleukin-35 inhibited the production of histamine and pro-inflammatory cytokines through suppression MAPKs pathway in HMC-1 cells

   Background

   IL-35 is a newly anti-inflammatory cytokine that belongs to the IL-12 family. Mast cells, as one of the major effector cells in the immune...

   Li-xin Fu, Tao Chen, ... Zai-pei Guo in Allergy, Asthma & Clinical Immunology

   Article Open access 17 April 2021
   

9. Analysis for interaction between interleukin-35 genes polymorphisms and risk factors on susceptibility to coronary heart disease in the Chinese Han population

   Background

   The relationship between IL-35 genes polymorphism and susceptibility to coronary heart disease has not been tested in the largest Han...

   Hu Li, Ying-Xue Liu, ... Kui Wang in BMC Cardiovascular Disorders

   Article Open access 06 January 2021
   

10. Interleukin-35 Promotes Th9 Cell Differentiation in IgG4-Related Disorders: Experimental Data and Review of the Literature

    IgG4-related disease (IgG4-RD) is characterized by intense infiltration of IgG4-positive plasma cells in affected organs. However, the mechanisms...

    Jun Zhang, Min Lian, ... **ong Ma in Clinical Reviews in Allergy & Immunology

    Article 25 July 2020
    

11. Interleukin-35 Suppresses CD8⁺ T Cell Activity in Patients with Viral Hepatitis-Induced Acute-on-Chronic Liver Failure

    Background

    Interleukin (IL)-35 is a newly indentified cytokine and induces immunotolerance via suppression of CD8 ⁺ T cell activity in chronic viral...

    Lanlan Yang, Qian Zhang, ... Zhen**g ** in Digestive Diseases and Sciences

    Article 24 January 2020
    

12. Interleukin-35 promotes the differentiation of regulatory T cells and suppresses Th2 response in IgG4-related type 1 autoimmune pancreatitis

    Background

    IgG4-related disease (IgG4-RD) is a systemic inflammatory disease, which includes type 1 autoimmune pancreatitis (AIP). Interleukin-35...

    Takashi Ito, Toshihiro Tanaka, ... Kazuichi Okazaki in Journal of Gastroenterology

    Article 06 May 2020
    

13. Role of interleukin-35 in rheumatoid arthritis pathogenesis and its relation to disease activity and joint damage

    Aim

    This study aimed to discuss the role of interleukin-35 (IL-35) in the pathogenesis of rheumatoid arthritis (RA) and its relation to disease...

    Nahed El-sayed El-sayed Akl, Soheir Mohammed Abd El-Halim, ... Shymaa Ahmed Hablas in Egyptian Rheumatology and Rehabilitation

    Article Open access 15 July 2019

14. Estimation of the tissue and serum levels of IL-35 in Mycosis fungoides: a case-control study

    Mycosis fungoides (MF) is the most common primary cutaneous T-cell lymphoma (CTCL) with its etiology not yet fully understood. Interleukin (IL)-35 is...

    Maha Fathy Elmasry, Yasmine Ahmed Obaid, ... Sally Sameh Doss in Archives of Dermatological Research

    Article Open access 08 June 2024
    

15. Diagnostic and prognostic role of serum interleukin-6 and carotid ultrasonography to detect subclinical atherosclerosis in patients with RA and ANCA-associated vasculitis

    ANCA-associated vasculitis (AAV) can affect multiple organs with severe life-threatening manifestations. Disease monitoring is difficult due to a...

    Velichka Popova, Mariela Geneva-Popova, ... Rositsa Karalilova in Rheumatology International

    Article 30 March 2024
    

16. Profiles of plasma interleukin-6 and interleukin-10 in relation to some haematologic alterations following colo-peritoneo-cystoplasty in dogs

    Systemic inflammatory response to surgical interventions has been characterized by an orchestrated interplay of endogenous mediatory cytokines and...

    Sa’idu Tanko Muhammad, Cheh Augustine Awasum, ... Joseph Olusegun Ayo in Comparative Clinical Pathology

    Article 19 May 2023
    

17. Brazilian green propolis prevent Alzheimer’s disease-like cognitive impairment induced by amyloid beta in mice

    Background

    The increasing incidence of cognitive impairment has become a health problem in the aging society. Owing to its antioxidant and...

    Takashi Ito, Tomomi Degawa, Nobuaki Okumura in BMC Complementary Medicine and Therapies

    Article Open access 17 November 2023
    

18. Serum interleukin-23 levels: relation to depression, anxiety, and disease activity in psoriatic arthritis patients

    Objectives

    Assessment of serum levels of IL-23 in PsA patients and its correlation with depression, anxiety, and disease activity.

    Methods ...

    Samar Abdalhamed Tabra, Salwa Elmorsy abd Elghany, ... Mohammed Hassan Abu-Zaid in Clinical Rheumatology

    Article Open access 21 July 2022
    

19. Severely complicated ear infection in a patient treated with ixekizumab: a case report

    We report a case of a severe ear infection in a 35-year-old man treated with ixekizumab for psoriasis. Ixekizumab is a humanized monoclonal antibody...

    Léonore Maertens, Naomi Pollet, ... Elke Loos in European Archives of Oto-Rhino-Laryngology

    Article 08 July 2024
    

20. Incidence of pulmonary hypertension in COPD and its relation to inflammatory marker interleukin-1

    Background

    Many COPD patients present with severe PH defined by a pulmonary vascular resistance (PVR) > 5 WU as measured by right heart...

    Sherif Ahmed Eissa, Youssef Mohamed Amin Soliman, ... Nashwa Ahmed Amin in The Egyptian Journal of Bronchology

    Article Open access 13 April 2024