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Traumatic inflammatory response: pathophysiological role and clinical value of cytokines
Severe trauma is an intractable problem in healthcare. Patients have a widespread immune system response that is complex and vital to survival....
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Postoperative inflammatory response in colorectal cancer surgery: a meta-analysis
PurposeSurgical removal of the cancerous tissue remains the cornerstone of curative treatment for colorectal cancer and results in an inflammatory...
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Impact of minimal invasive extracorporeal circulation on systemic inflammatory response – a randomized trial
BackgroundExtracorporeal circulation causes a systemic inflammatory response, that may cause postoperative haemodynamic instability and end-organ...
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Limited impact of traumatic brain injury on the post-traumatic inflammatory cellular response
PurposeTrauma triggers a systemic inflammatory cellular response due to tissue damage, potentially leading to a secondary immune deficiency. Trauma...
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Vaginal Bacteria Elicit Acute Inflammatory Response in Fallopian Tube Organoids
To facilitate in vitro mechanistic studies in pelvic inflammatory disease and subsequent tubal factor infertility, we sought to establish patient...
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Prognostic value of the systemic inflammatory index (SII) and systemic inflammatory response index (SIRI) in patients with traumatic spinal cord injury
PurposeThe overwhelming inflammatory response plays a critical role in the secondary injury cascade of traumatic spinal cord injury (tSCI). The...
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Higher inflammatory response in hepatocellular carcinoma is associated with immune cell infiltration and a better outcome
Background and aimsHepatocellular carcinoma (HCC) often develops from chronic liver inflammation. Inflammation within a tumor can either promote...
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The impact of prior exposure to hypoglycaemia on the inflammatory response to a subsequent hypoglycaemic episode
BackgroundHypoglycaemia has been shown to induce a systemic pro-inflammatory response, which may be driven, in part, by the adrenaline response....
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MicroRNA-223-3p downregulates the inflammatory response in preeclampsia placenta via targeting NLRP3
ObjectiveTo investigate the regulatory role of miR-223-3p in the inflammatory response of PE placenta.
MethodsPE and normal placental tissues were...
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Gentiopicroside ameliorates the lipopolysaccharide-induced inflammatory response and hypertrophy in chondrocytes
PurposeThis study aimed to evaluate the protective effects of gentiopicroside against lipopolysaccharide-induced chondrocyte inflammation.
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Resveratrol ameliorates glioblastoma inflammatory response by reducing NLRP3 inflammasome activation through inhibition of the JAK2/STAT3 pathway
ObjectivesThe aim of this study was to investigate the anti-tumor effect of resveratrol (RSV) on glioblastoma (GBM) and its specific mechanism in...
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Fetal inflammatory response and risk for psychiatric disorders
Inflammation contributes to numerous neuropsychiatric disorders, especially those that first appear in childhood. Maternal intrauterine environment,...
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Impact of fetal inflammatory response on the severity of necrotizing enterocolitis in preterm infants
ObjectiveNeonates born with fetal inflammatory response (FIR) are at increased risk for adverse neonatal outcomes. Our objective was to determine...
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Age-dependent inflammatory response is altered in an ex vivo model of bacterial pneumonia
BackgroundAging is associated with an increased incidence and mortality of Pseudomonas aeruginosa -induced pneumonias. This might be partly due to...
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Heparan sulfate acts as an activator of the NLRP3 inflammasome promoting inflammatory response in the development of acute pancreatitis
BackgroundAccumulating evidence has shown that the NOD-like receptor protein 3 (NLRP3) inflammasome plays a crucial role in the inflammatory cascades...
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Spatial Variation in the Inflammatory Response of House Sparrows in their Native Range
Characterizing spatial differences in wildlife immunity is the first step to identify environmental drivers of host defense and disease risks. The...
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Effects of edaravone dexborneol on functional outcome and inflammatory response in patients with acute ischemic stroke
BackgroundEdaravone dexborneol has been reported as an effective neuroprotective agent in the treatment of acute ischemic stroke (AIS). This study...
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Immediate inflammatory response to mechanical circulatory support in a porcine model of severe cardiogenic shock
BackgroundIn selected cases of cardiogenic shock, veno-arterial extracorporeal membrane oxygenation (V-A ECMO) is combined with trans valvular micro...
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Systemic inflammatory response index as an independent predictor of severity in patients with obstructive sleep apnea
BackgroundChronic inflammation plays a crucial role in develo** various cardiovascular and metabolic disorders. Obstructive sleep apnea (OSA) is a...
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Saikosaponin D alleviates inflammatory response of osteoarthritis and mediates autophagy via elevating microRNA-199-3p to target transcription Factor-4
ObjectiveThis study was to investigate the underlying mechanism by which Saikosaponin D (SSD) mitigates the inflammatory response associated with...
