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  1. No robust reduction of infarct size and no-reflow by metoprolol pretreatment in adult Göttingen minipigs

    Whereas prior experiments in juvenile pigs had reported infarct size reduction by intravenous metoprolol early during myocardial ischaemia, two major...

    Petra Kleinbongard, Helmut Raphael Lieder, ... Gerd Heusch in Basic Research in Cardiology
    Article Open access 08 June 2023
  2. Infarct size, inflammatory burden, and admission hyperglycemia in diabetic patients with acute myocardial infarction treated with SGLT2-inhibitors: a multicenter international registry

    Background

    The inflammatory response occurring in acute myocardial infarction (AMI) has been proposed as a potential pharmacological target....

    Pasquale Paolisso, Luca Bergamaschi, ... Carmine Pizzi in Cardiovascular Diabetology
    Article Open access 15 May 2022
  3. Aspirin Blocks the Infarct-Size Limiting Effect of Ischemic Postconditioning in the Rat

    Background

    Ischemic postconditioning (PostC), repetitive cycles of re-occlusion, and reperfusion of the infarct-related artery immediately after...

    Yochai Birnbaum, Regina Ye, Yumei Ye in Cardiovascular Drugs and Therapy
    Article 17 August 2021
  4. The Infarct-Limiting Effect of Remote Ischemic Conditioning in Rats Is Not Affected by Aspirin

    Purpose

    Remote ischemic conditioning (RIC) has been shown to be a powerful cardioprotective therapy in animal models. However, a protective effect in...

    M. V. Basalay, James M. Downey, ... D. M. Yellon in Cardiovascular Drugs and Therapy
    Article Open access 20 December 2023
  5. Deep learning reconstruction for improving the visualization of acute brain infarct on computed tomography

    Purpose

    This study aimed to investigate the impact of deep learning reconstruction (DLR) on acute infarct depiction compared with hybrid iterative...

    Naomasa Okimoto, Koichiro Yasaka, ... Osamu Abe in Neuroradiology
    Article Open access 22 November 2023
  6. FLAIR signal intensity ratio predicts small subcortical infarct early neurologic deterioration: a cross-sectional study

    Purpose

    Prior studies have used the fluid-attenuated inversion recovery sequence signal intensity ratio (FLAIR-SIR) to predict those with an...

    Eric D. Goldstein, Fayez H. Fayad, ... Shadi Yaghi in Neuroradiology
    Article 26 January 2024
  7. Osteopontin promotes infarct repair

    Understanding how macrophages promote myocardial repair can help create new therapies for infarct repair. We aimed to determine what mechanisms...

    Itai Rotem, Tal Konfino, ... Jonathan Leor in Basic Research in Cardiology
    Article 14 October 2022
  8. Infarct quantification with cardiovascular magnetic resonance using "standard deviation from remote" is unreliable: validation in multi-centre multi-vendor data

    Background

    The objective of the study was to investigate variability and agreement of the commonly used image processing method “n-SD from remote” and...

    Einar Heiberg, Henrik Engblom, ... Håkan Arheden in Journal of Cardiovascular Magnetic Resonance
    Article Open access 07 November 2022
  9. Second-generation extracellular matrix patch for epicardial infarct repair

    Current myocardial infarction treatments focus on improving hemodynamics rather than addressing the problem of lost myocardium impairing left...

    Arjun Bhatt, Michael J. Bates, ... Walter Douglas Boyd in Journal of Cardiothoracic Surgery
    Article Open access 01 September 2023
  10. A rare cause of pain abdomen—renal artery thrombosis with renal infarct

    We report here a case of 56-year-old male presented to emergency with acute onset severe abdominal pain in right lumbar region and with significant...

    D. Saikiran, V. K. Srinivas, ... M. Harismitha in The Egyptian Journal of Internal Medicine
    Article Open access 03 July 2023
  11. Brush sign and collateral supply as potential markers of large infarct growth after successful thrombectomy

    Objectives

    To investigate the relationships between brush sign and cerebral collateral status on infarct growth after successful thrombectomy.

    ...
    Alexandre Bani-Sadr, Dylan Pavie, ... Yves Berthezene in European Radiology
    Article 12 January 2023
  12. Hyperglycemia, inflammatory response and infarct size in obstructive acute myocardial infarction and MINOCA

    Background

    Hyperglycemia has been associated with increased inflammatory indexes and larger infarct sizes in patients with obstructive acute...

    Pasquale Paolisso, Alberto Foà, ... Carmine Pizzi in Cardiovascular Diabetology
    Article Open access 02 February 2021
  13. Effect of remote ischaemic conditioning on infarct size and remodelling in ST-segment elevation myocardial infarction patients: the CONDI-2/ERIC-PPCI CMR substudy

    The effect of limb remote ischaemic conditioning (RIC) on myocardial infarct (MI) size and left ventricular ejection fraction (LVEF) was...

    Rohin Francis, Jun Chong, ... Derek J. Hausenloy in Basic Research in Cardiology
    Article Open access 14 October 2021
  14. A review of literature on Compound 21-loaded gelatin nanoparticle: a promising nose-to-brain therapy for multi-infarct dementia

    Multi-infarct dementia (MID) is described as a chronic progressive decline in cortical cognitive function due to the occurrence of multiple infarcts...

    Bryan Gervais de Liyis, Jane Carissa Sutedja, ... I. Putu Eka Widyadharma in The Egyptian Journal of Neurology, Psychiatry and Neurosurgery
    Article Open access 26 January 2023
  15. Comparing the findings and diagnostic sensitivity of cardiovascular magnetic resonance in biopsy confirmed acute myocarditis with infarct-like vs. heart failure presentation

    Background

    Cardiovascular magnetic resonance (CMR) is considered the reference imaging modality in providing a non-invasive diagnosis of acute...

    Karim Hassan, Anton Doubell, ... Philip Herbst in Journal of Cardiovascular Magnetic Resonance
    Article Open access 07 December 2022
  16. The relationship between infarct volume and high sensitivity troponin I level in patients diagnosed with ischemic stroke

    Background

    Various biomarkers and clinical variables are used to determine the probability risk, diagnosis, and the prognosis of acute ischemic...

    Arif Aksu, Akkan Avci, ... Ferhat Icme in Irish Journal of Medical Science (1971 -)
    Article 06 June 2022
  17. Left Ventricular Assist Devices for Acute Myocardial Infarct Size Reduction: Meta-analysis

    We conducted a meta-analysis of preclinical studies that tested left ventricular assist device (LVAD) therapy for reducing myocardial infarct size in...

    Satoshi Miyashita, Taro Kariya, ... Kiyotake Ishikawa in Journal of Cardiovascular Translational Research
    Article 28 August 2020
  18. Common Data Elements Analysis of Mechanical Thrombectomy Clinical Trials for Acute Ischemic Stroke with Large Core Infarct

    Background

    Clinical trials addressing large core acute ischemic stroke (AIS) are ongoing across multiple international groups. Future development of...

    Mohamed Sobhi Jabal, Mohamed K. Ibrahim, ... David F. Kallmes in Clinical Neuroradiology
    Article 15 December 2022
  19. Early surgical outcomes of a modified infarct exclusion technique in acute post-myocardial infarction ventricular septal rupture: a single-centre experience

    Introduction

    Operative mortality in an acute post-myocardial infarction (AMI) ventricular septal rupture (VSR) is high. In addition to ventricular...

    Pankaj Aggarwal, Sachin Mahajan, ... Vidur Bansal in Indian Journal of Thoracic and Cardiovascular Surgery
    Article 10 February 2023
  20. Sodium–glucose cotransporter 2 inhibitors reduce myocardial infarct size in preclinical animal models of myocardial ischaemia–reperfusion injury: a meta-analysis

    Aims/hypothesis

    Large cardiovascular outcome trials demonstrated that the cardioprotective effects of sodium–glucose cotransporter 2 (SGLT2)...

    Alex Ali Sayour, Csilla Celeng, ... Tamás Radovits in Diabetologia
    Article Open access 23 January 2021
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