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No robust reduction of infarct size and no-reflow by metoprolol pretreatment in adult Göttingen minipigs
Whereas prior experiments in juvenile pigs had reported infarct size reduction by intravenous metoprolol early during myocardial ischaemia, two major...
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Infarct size, inflammatory burden, and admission hyperglycemia in diabetic patients with acute myocardial infarction treated with SGLT2-inhibitors: a multicenter international registry
BackgroundThe inflammatory response occurring in acute myocardial infarction (AMI) has been proposed as a potential pharmacological target....
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Aspirin Blocks the Infarct-Size Limiting Effect of Ischemic Postconditioning in the Rat
BackgroundIschemic postconditioning (PostC), repetitive cycles of re-occlusion, and reperfusion of the infarct-related artery immediately after...
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The Infarct-Limiting Effect of Remote Ischemic Conditioning in Rats Is Not Affected by Aspirin
PurposeRemote ischemic conditioning (RIC) has been shown to be a powerful cardioprotective therapy in animal models. However, a protective effect in...
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Deep learning reconstruction for improving the visualization of acute brain infarct on computed tomography
PurposeThis study aimed to investigate the impact of deep learning reconstruction (DLR) on acute infarct depiction compared with hybrid iterative...
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FLAIR signal intensity ratio predicts small subcortical infarct early neurologic deterioration: a cross-sectional study
PurposePrior studies have used the fluid-attenuated inversion recovery sequence signal intensity ratio (FLAIR-SIR) to predict those with an...
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Osteopontin promotes infarct repair
Understanding how macrophages promote myocardial repair can help create new therapies for infarct repair. We aimed to determine what mechanisms...
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Infarct quantification with cardiovascular magnetic resonance using "standard deviation from remote" is unreliable: validation in multi-centre multi-vendor data
BackgroundThe objective of the study was to investigate variability and agreement of the commonly used image processing method “n-SD from remote” and...
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Second-generation extracellular matrix patch for epicardial infarct repair
Current myocardial infarction treatments focus on improving hemodynamics rather than addressing the problem of lost myocardium impairing left...
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A rare cause of pain abdomen—renal artery thrombosis with renal infarct
We report here a case of 56-year-old male presented to emergency with acute onset severe abdominal pain in right lumbar region and with significant...
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Brush sign and collateral supply as potential markers of large infarct growth after successful thrombectomy
ObjectivesTo investigate the relationships between brush sign and cerebral collateral status on infarct growth after successful thrombectomy.
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Hyperglycemia, inflammatory response and infarct size in obstructive acute myocardial infarction and MINOCA
BackgroundHyperglycemia has been associated with increased inflammatory indexes and larger infarct sizes in patients with obstructive acute...
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Effect of remote ischaemic conditioning on infarct size and remodelling in ST-segment elevation myocardial infarction patients: the CONDI-2/ERIC-PPCI CMR substudy
The effect of limb remote ischaemic conditioning (RIC) on myocardial infarct (MI) size and left ventricular ejection fraction (LVEF) was...
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A review of literature on Compound 21-loaded gelatin nanoparticle: a promising nose-to-brain therapy for multi-infarct dementia
Multi-infarct dementia (MID) is described as a chronic progressive decline in cortical cognitive function due to the occurrence of multiple infarcts...
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Comparing the findings and diagnostic sensitivity of cardiovascular magnetic resonance in biopsy confirmed acute myocarditis with infarct-like vs. heart failure presentation
BackgroundCardiovascular magnetic resonance (CMR) is considered the reference imaging modality in providing a non-invasive diagnosis of acute...
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The relationship between infarct volume and high sensitivity troponin I level in patients diagnosed with ischemic stroke
BackgroundVarious biomarkers and clinical variables are used to determine the probability risk, diagnosis, and the prognosis of acute ischemic...
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Left Ventricular Assist Devices for Acute Myocardial Infarct Size Reduction: Meta-analysis
We conducted a meta-analysis of preclinical studies that tested left ventricular assist device (LVAD) therapy for reducing myocardial infarct size in...
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Common Data Elements Analysis of Mechanical Thrombectomy Clinical Trials for Acute Ischemic Stroke with Large Core Infarct
BackgroundClinical trials addressing large core acute ischemic stroke (AIS) are ongoing across multiple international groups. Future development of...
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Early surgical outcomes of a modified infarct exclusion technique in acute post-myocardial infarction ventricular septal rupture: a single-centre experience
IntroductionOperative mortality in an acute post-myocardial infarction (AMI) ventricular septal rupture (VSR) is high. In addition to ventricular...
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Sodium–glucose cotransporter 2 inhibitors reduce myocardial infarct size in preclinical animal models of myocardial ischaemia–reperfusion injury: a meta-analysis
Aims/hypothesisLarge cardiovascular outcome trials demonstrated that the cardioprotective effects of sodium–glucose cotransporter 2 (SGLT2)...