Search
Search Results
-
Immunoglobulins in COVID-19 pneumonia: from the acute phase to the recovery phase
BackgroundCOVID-19 pneumonia causes hyperinflammatory response that culminates in acute respiratory syndrome (ARDS) related to increased multiorgan...
-
Prevalence of aortic aneurysmal sac expansion using CTA in type II endoleak: comparison between endoleak visualization in CTA phase and in delayed phase
BackgroundTo compare the prevalence of aneurysmal sac expansion in type II endoleak (T2E) presenting on CTA phase with T2E presenting on delayed...
-
Luteal phase support in assisted reproductive technology
Infertility affects one in six couples, with in vitro fertilization (IVF) offering many the chance of conception. Compared to the solitary oocyte...
-
Phase separation in cGAS-STING signaling
Biomolecular condensates formed by phase separation are widespread and play critical roles in many physiological and pathological processes....
-
Phase 2A Learnings Incorporated into RewinD-LB, a Phase 2B Clinical Trial of Neflamapimod in Dementia with Lewy Bodies
BackgroundIn an exploratory 91-participant phase 2a clinical trial (AscenD-LB, NCT04001517) in dementia with Lewy bodies (DLB), neflamapimod showed...
-
Management and outcome of patients with chronic myeloid leukemia in blast phase in the tyrosine kinase inhibitor era – analysis of the European LeukemiaNet Blast Phase Registry
Blast phase (BP) of chronic myeloid leukemia (CML) still represents an unmet clinical need with a dismal prognosis. Due to the rarity of the...
-
The timing phase affected the inconsistency of APHE subtypes of liver observations in patients at risk for HCC on the multi-hepatic arterial phase imaging
ObjectiveTo investigate whether liver observations in patients at risk for hepatocellular carcinoma (HCC) display inconsistent arterial phase...
-
Comparison of luteal phase stimulation with follicular phase stimulation in poor ovarian response: a single-blinded randomized controlled trial
BackgroundIn the last decade, luteal-phase ovarian stimulation (LPOS) has been suggested as an alternative controlled ovarian stimulation (COS)...
-
Evaluation of liver metastasis in patients with breast cancer: Comparison of single-phase abdominopelvic CT and multi-phase liver CT
PurposeTo compare the usefulness of multi-phase liver CT and single-phase abdominopelvic CT (APCT) in evaluating liver metastasis in newly diagnosed...
-
Decreased Serum Apolipoprotein CIII in the Acute Phase of Kawasaki Disease
Plasma exchange is an effective treatment for Kawasaki disease (KD), suggesting that plasma from patients with KD bears its causative agents. The aim...
-
Do Early Phase Oncology Trials Predict Clinical Efficacy in Subsequent Biomarker-Enriched Phase III Randomized Trials?
BackgroundPromising early phase trial results of biomarker-targeted therapies have occasionally led to regulatory approval.
Objective ...
-
A first-in-human, open-label Phase 1b and a randomised, double-blind Phase 2a clinical trial in recent-onset type 1 diabetes with AG019 as monotherapy and in combination with teplizumab
Aims/hypothesisWe hypothesised that islet beta cell antigen presentation in the gut along with a tolerising cytokine would lead to antigen-specific...
-
Temporal imprecision of phase coherence in schizophrenia and psychosis—dynamic mechanisms and diagnostic marker
Schizophrenia (SCZ) is a complex disorder in which various pathophysiological models have been postulated. Brain imaging studies using EEG/MEG and...
-
Pharmacokinetics of Roflumilast Cream in Chronic Plaque Psoriasis: Data from Phase I to Phase III Studies
BackgroundMost patients with chronic plaque psoriasis receive topical treatment; however, available options lack a balance of efficacy with long-term...
-
Determinants of phase angle in Japanese patients with diabetes
Phase angle, obtained using bioelectrical impedance analysis, non-invasively reflects the whole-body cellular condition and nutritional status and...
-
Role of Dydrogesterone for Luteal Phase Support in Assisted Reproduction
Clinical outcomes of in vitro fertilization (IVF) have significantly improved over the years with the advent of the frozen–thawed embryo transfer...
-
Towards phase-sensitive optical coherence tomography in smart laser osteotomy: temperature feedback
Thermal effects during bone surgery pose a common challenge, whether using mechanical tools or lasers. An irrigation system is a standard solution to...
-
Looking ahead in early-phase trial design to improve the drug development process: examples in oncology
BackgroundClinical trial design must consider the specific resource constraints and overall goals of the drug development process (DDP); for example,...
-
Does delayed phase imaging in CT angiography provide additional information in patients with suspected active bleeding?
PurposeWe hypothesize that delayed phase imaging does not provide additional diagnostic information in patients who undergo multi-phasic CTA for...
-
Automatic surgical phase recognition-based skill assessment in laparoscopic distal gastrectomy using multicenter videos
BackgroundGastric surgery involves numerous surgical phases; however, its steps can be clearly defined. Deep learning-based surgical phase...
