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Variation of PetCO2 during incremental exercise and severity of IPAH and CTEPH
Background and objectiveEnd-tidal PCO 2 (PetCO 2 ) patterns during exercise testing as well as ventilatory equivalents for CO 2 have been reported for...
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ECMO Bridge to Lung Transplant in Children with Idiopathic Pulmonary Arterial Hypertension
Idiopathic pulmonary arterial hypertension (IPAH) represents an important clinical indication for lung transplant (LTx) in children. Recent trends...
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Fractional exhaled nitric oxide in idiopathic pulmonary arterial hypertension and mixed connective tissue disease complicating pulmonary hypertension
BackgroundFractional exhaled nitric oxide (FeNO) has been extensively studied in various causes of pulmonary hypertension (PH), but its utility as a...
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Serum PM20D1 levels in patients with idiopathic pulmonary arterial hypertension and its clinical significance
ObjectiveThis study aimed to investigate the serum levels of Peptidase M20 domain containing 1 (PM20D1) in idiopathic pulmonary arterial hypertension...
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Association of non-insulin-based insulin resistance indices with disease severity and adverse outcome in idiopathic pulmonary arterial hypertension: a multi-center cohort study
BackgroundInsulin resistance (IR) plays an important role in the pathophysiology of cardiovascular disease. Recent studies have shown that diabetes...
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Impact of diabetes mellitus on disease severity and patient survival in idiopathic pulmonary arterial hypertension: data from the Polish multicentre registry (BNP-PL)
BackgroundRecent studies revealed that alterations in glucose and lipid metabolism in idiopathic pulmonary arterial hypertension (IPAH) are...
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Pregnancy outcomes in women with pulmonary hypertension: a retrospective study in China
BackgroundIn recent years, with the development of monitoring conditions and the application of pulmonary vascular-targeted drugs, pregnancy outcomes...
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Differential expression and analysis of extrachromosomal circular DNAs as serum biomarkers in pulmonary arterial hypertension
BackgroundExtrachromosomal circular DNAs (eccDNAs) have been reported to play a key role in the occurrence and development of various diseases....
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CircGSAP alleviates pulmonary microvascular endothelial cells dysfunction in pulmonary hypertension via regulating miR-27a-3p/BMPR2 axis
BackgroundOur previous study showed that circular RNA-gamma-secretase-activating protein (circGSAP) was down-regulated in pulmonary microvascular...
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Resistin predicts disease severity and survival in patients with pulmonary arterial hypertension
BackgroundAbnormal remodeling of distal pulmonary arteries in patients with pulmonary arterial hypertension (PAH) leads to progressively increased...
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Lung Transplantation for Pulmonary Vascular Disease in Children: A United Network for Organ Sharing Analysis
Pulmonary vascular disease (PVD) represents an important clinical indication for lung transplant (LTx) in infants, children, and adolescents. There...
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Role and predictive value of microRNAs 204 and 210 in the diagnosis of pulmonary arterial hypertension and the distinction between idiopathic, systemic sclerosis, and schistosomiasis-associated pulmonary arterial hypertension
BackgroundPulmonary arterial hypertension is most of the time diagnosed late in the course of the disease and necessitates right cardiac...
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Predictors of the response to phosphodiesterase-5 inhibitors in pulmonary arterial hypertension: an analysis of the Spanish registry
BackgroundAchieving and maintaining a low-risk profile is associated with favorable outcome in pulmonary arterial hypertension (PAH). The effects of...
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Pulmonary hypertension in connective tissue diseases: epidemiology, pathogenesis, and treatment
AbstractPulmonary hypertension (PH) is a clinical condition characterized by increased pulmonary arterial pressure arising from a heterogeneous range...
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Predictive value of chest HRCT for survival in idiopathic pulmonary arterial hypertension
BackgroundLittle attention has been paid to chest high resolution computed tomography (HRCT) findings in idiopathic pulmonary arterial hypertension...
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Clinical phenotypes, hemodynamic characteristics and prognosis of Chinese patients with systemic sclerosis-associated precapillary pulmonary hypertension: a retrospective study
IntroductionSystemic sclerosis (SSc) is associated with interstitial lung disease (ILD) and pulmonary arterial hypertension (PAH). This study aimed...
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EspE3 plays a role in the pathogenicity of avian pathogenic Escherichia coli
APEC encodes multiple virulence factors that have complex pathogenic mechanisms. In this study, we report a virulence factor named EspE3, which can...
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Higher circulating Trimethylamine N-oxide levels are associated with worse severity and prognosis in pulmonary hypertension: a cohort study
BackgroundTrimethylamine N-oxide (TMAO), the gut microbiota-dependent metabolite, is a potential biomarker in several cardiovascular diseases....
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Outcomes of idiopathic pulmonary arterial hypertension in Japanese children: a retrospective cohort study
Recently, targeted therapy has been developed for idiopathic pulmonary arterial hypertension (IPAH). Studies evaluating the prognosis of IPAH have...
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Peripheral microangiopathy in precapillary pulmonary hypertension: a nailfold video capillaroscopy prospective study
BackgroundAlthough pulmonary vascular bed has been the main subject of research for many years in pulmonary hypertension (PH), interest has recently...
