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Persistent coagulopathy after gunshot traumatic brain injury: the importance of INR and the SPIN score
IntroductionPenetrating ballistic brain injury (gunshot traumatic brain injury or GTBI) is associated with a high mortality. Admission Glascow Coma...
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Vitamin K prophylaxis in neonates: comparing two different oral regimens
ObjectiveThis prospective study compared PIVKA-II and PT-INR levels in infants who received two vitamin K (VK) prophylactic regimens.
Methods ...
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Spontaneous coronary artery dissection in a young patient with antiphospholipid syndrome
A 28-year-old man diagnosed with triple positive antiphospholipid syndrome (APS) and undergoing warfarin experienced three separate admissions to the...
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Demystifying post-hepatectomy enzyme kinetics for the surgical learner: an analysis of 989 major hepatectomies
PurposeFew resources exist for surgical learners in interpreting trends in biochemical markers following major hepatic resections.
Methods ...
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A clinical study of genetic testing to guide the dosing of warfarin after heart valve replacement
ObjectiveTo explore the role of genetic testing of VKORC1 and CYP2C9 in determining the dosage of warfarin after aortic valve replacement.
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Post-thrombolytic coagulopathy and complications in patients with pulmonary embolism treated with fixed-dose systemic alteplase
BackgroundAlteplase treatment can cause a systemic coagulopathy although the incidence and contributory factors are unknown in pulmonary embolism...
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Nationwide survey for patients with acute-on-chronic liver failure occurring between 2017 and 2019 and diagnosed according to proposed Japanese criteria
BackgroundThe significance of the 2018 Japanese diagnostic criteria for acute-on-chronic liver failure (ACLF) has not yet been evaluated.
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Comparison of thromboelastographic profiles in pediatric patients with congenital heart disease according to existence of cyanosis
PurposeCongenital heart disease (CHD) is divided into two groups according to cyanosis status. Cyanotic CHD has a low level of systemic oxygenation...
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Predictors and Outcomes of Post-transjugular Intrahepatic Portosystemic Shunt Liver Failure in Patients with Cirrhosis
BackgroundPost-transjugular intrahepatic portosystemic shunt (TIPS) liver failure (PTLF) is a serious complication of TIPS procedure with poor...
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A MASsive attack: a pediatric case of macrophage activation syndrome complicated by DIC as an onset of systemic juvenile idiopathic arthritis successfully treated with anakinra and review of the literature
Macrophage activation syndrome (MAS) is one of the most severe complications of systemic juvenile idiopathic arthritis (sJIA). Around 10% of patients...
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Limited diagnostic value of liver stiffness for clinically significant portal hypertension in HBV-related cirrhosis
PurposeHepatic venous pressure gradient ( HVPG ) is the gold standard for portal pressure in cirrhosis, but most previous studies focused on the...
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Double whammy: anticoagulant-related nephropathy with leukocytoclastic vasculitis due to warfarin
Anticoagulation-related nephropathy (ARN) is a rare form of acute kidney injury where the use of anticoagulation causes hemorrhage in various...
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Retrospectively diagnosed autoimmune VWF deficiency in a patient with repeated hemorrhagic events after two common colds
Autoimmune von Willebrand factor (VWF) deficiency (AiVWFD) caused by anti-VWF autoantibodies is a rare bleeding disorder, whereas “non-immune”...
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Augmenting Community Diagnosis of Safe Ear Disease Through Tele-Myringoscopy with Borescope Using AIML Techniques
This study utilized AIML (artificial intelligence & machine learning) techniques to analyze 115 images of central perforation of tympanic membrane...
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Human umbilical cord mesenchymal stem cell transfusion in immune non-responders with AIDS: a multicenter randomized controlled trial
We examined the safety and efficacy of human umbilical cord mesenchymal stem cell (hUC-MSC) infusion for immune non-responder (INR) patients with...
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The effect of vitamin K on prothrombin time in critically ill patients: an observational registry study
BackgroundPrevious studies have indicated that vitamin K deficiency is common in non-bleeding critically ill patients with slightly prolonged...
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Low mortality despite temporary liver dysfunction in severe courses of acute hepatitis E
BackgroundHepatitis E virus (HEV) infection can cause severe viral hepatitis and eventually liver failure. We aim to provide novel data on the...
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Brazilian experience with caplacizumab in acquired thrombotic thrombocytopenic purpura: outcomes of the expanded access program
Acquired thrombotic thrombocytopenic purpura (aTTP) is a rare disease with an acute and severe clinical presentation. The anti-von Willebrand factor...
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Double-blind placebo-controlled randomized trial of N-acetylcysteine infusion following live donor liver transplantation
BackgroundThe role of N -acetylcysteine (NAC) in improving outcomes following live donor liver transplantation (LDLT) is not well established. We...
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Assessment of carotid atherosclerosis in Egyptian chronic hepatitis C patients after treatment by direct-acting antiviral drugs
BackgroundRecent studies suggested association between hepatitis C virus (HCV) infection and cardiovascular disorders, including carotid...
