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Acute and long-term toxicity in primary hypofractionated external photon radiation therapy in patients with localized prostate cancer
BackgroundCompelling evidence exists for the iso-effectiveness and safety of moderate hypofractionated radiotherapy (Hypo-RT) schedules [1, 2]....
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Moderate hypofractionated radiation therapy and pathologic response for soft tissue sarcomas (STS) of limbs and trunk: experience from a tertiary cancer center
BackgroundPreoperative radiation therapy following by limb-sparing or conservative surgery is a standard approach for limb and trunk STS. Data...
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Moderately hypofractionated versus conventionally fractionated radiation therapy with temozolomide for young and fit patients with glioblastoma: an institutional experience and meta-analysis of literature
PurposeShorter hypofractionated radiation therapy (HF-RT) schedules may have radiobiological, patient convenience and healthcare resource advantages...
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Hypofractionated whole breast irradiation in association with hypofractionated or normofractionated boost to the tumor bed in early breast cancer: tolerance and efficacy analysis
BackgroundThe boost to the tumor bed improves local control in breast cancer and it is an important part of the breast conserving therapy. However,...
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Hypofractionated versus conventional fractionation external beam radiotherapy in intermediate and high risk localized prostate cancer
BackgroundProstate cancer is the second most common malignancy in men, and its incidence is increasing which is attributed to increased screening...
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Overview of Radiation Therapy in the Management of Localized and Metastatic Prostate Cancer
Purpose of ReviewThe goal is to describe the evolution of radiation therapy (RT) utilization in the management of localized and metastatic prostate...
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Changes in Radiation Therapy: New Ultrahypofractionated Radiation, Repeat Breast Conservation Therapy in the Management of Breast Recurrence with Re-irradiation, Proton Therapy
Purpose of ReviewManagement of breast cancer is multidisciplinary, balancing local and systemic control between treatment modalities. Surgical,...
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Favorable outcome in advanced pheochromocytoma and paraganglioma after hypofractionated intensity modulated radiotherapy
PurposeThe purpose of this study was to review outcomes of patients with advanced/metastatic pheochromocytoma/paraganglioma (PPGL) treated at our...
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Hypofractionated stereotactic re-irradiation for progressive glioblastoma: twelve years’ experience of a single center
PurposeWe aimed to evaluate the prognostic factors and the role of stereotactic radiotherapy (SRT) as a re-irradiation technique in the management of...
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Hypofractionated versus standard chemoradiotherapy in the definitive treatment of uterine cervix cancer: interim results of a randomized controlled clinical trial
PurposeConcurrent chemoradiation has been the mainstay of treatment for cervix cancer. We aimed to evaluate the non-inferiority of hypofractionated...
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Image-guided moderately hypofractionated radiotherapy for localized prostate cancer: a multicentric retrospective study (IPOPROMISE)
BackgroundModerate hypofractionated radiotherapy is a treatment option for the cure of localized prostate cancer (PCa) patients based on the results...
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Evidence-based guidelines for hypofractionated radiation in breast cancer: conclusions of the Catalan expert working group
IntroductionDaily, moderate hypofractionation has become standard treatment for breast cancer following breast-conserving surgery, although...
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A Japanese multi-institutional phase II study of moderate hypofractionated intensity-modulated radiotherapy with image-guided technique for prostate cancer
BackgroundThe aim of this multi-institutional phase II study was to confirm the safety and the potential efficacy of moderately hypofractionated...
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Immune Priming with Spatially Fractionated Radiation Therapy
Purpose of ReviewThis review aims to summarize the current preclinical and clinical evidence of nontargeted immune effects of spatially fractionated...
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Single fraction and hypofractionated radiosurgery for perioptic meningiomas—tumor control and visual outcomes: a systematic review and meta-analysis
Perioptic meningiomas, defined as those that are less than 3 mm from the optic apparatus, are challenging to treat with stereotactic radiosurgery...
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Let’s make size not matter: tumor control and toxicity outcomes of hypofractionated Gamma Knife radiosurgery for large brain metastases
PurposeManagement of patients with large brain metastases poses a clinical challenge, with poor local control and high risk of adverse radiation...
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Highly hypofractionated intensity-modulated radiation therapy for nonmetastatic prostate cancer with a simultaneous integrated boost to intraprostatic lesions: a planning study
PurposeThe purpose of this planning study was to develop an acceptable technique for highly hypofractionated intensity-modulated radiation therapy...
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Nodal and osseous oligometastatic prostate cancer: a cohort including the introduction of PSMA-PET/CT-guided stereotactic and hypofractionated radiotherapy with elective nodal therapy
PurposeOligometastatic prostate cancer is heavily investigated, and conventionally fractionated elective nodal treatment appears to increase...
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Dosimetric impact of rectum and bladder anatomy and intrafractional prostate motion on hypofractionated prostate radiation therapy
ObjectiveThe objective of this study was to evaluate the dosimetric impact on hypofractionated prostate radiation therapy of two geometric...
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Moderate hypofractionated post-prostatectomy radiation therapy is feasible and well tolerated: experience from a single tertiary cancer centre
PurposeConventional post-prostatectomy radiation therapy comprises 6.5–8 weeks of treatment, therefore, hypofractionated and shortened schemes arouse...
