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Pseudoprogression and hyperprogression in lung cancer: a comprehensive review of literature
PurposeImmune checkpoint inhibitors are associated with clinical benefit in lung cancer. However, response patterns to immunotherapy, including...
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Circulating regulatory T cells predict efficacy and atypical responses in lung cancer patients treated with PD-1/PD-L1 inhibitors
BackgroundImmune checkpoint inhibitors (ICIs) have become the standard of care for a variety of cancers, including non-small cell lung cancer...
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Hyperprogressive disease rarely occurs during checkpoint inhibitor treatment for advanced melanoma
IntroductionHyperprogression, characterized by a rapid acceleration in tumor growth, is a novel pattern of progression recently described in patients...
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Management of cutaneous melanoma: radiologists challenging and risk assessment
Melanoma patient remains a challenging for the radiologist, due to the difficulty related to the management of a patient more often in an advanced...
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Radiological artificial intelligence - predicting personalized immunotherapy outcomes in lung cancer
Personalized medicine has revolutionized approaches to treatment in the field of lung cancer by enabling therapies to be specific to each patient....
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Multi-omics and artificial intelligence predict clinical outcomes of immunotherapy in non-small cell lung cancer patients
In recent years, various types of immunotherapy, particularly the use of immune checkpoint inhibitors targeting programmed cell death 1 or programmed...
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Targeting NAD+ metabolism of hepatocellular carcinoma cells by lenvatinib promotes M2 macrophages reverse polarization, suppressing the HCC progression
BackgroundLowered nicotinamide adenine dinucleotide (NAD + ) levels in tumor cells drive tumor hyperprogression during immunotherapy, and its...
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Bildgebung bei Immuntherapie bei Tumorerkrankungen
Immunotherapeutic agents and in particular immune checkpoint inhibitors (ICI) have opened up extensive new therapeutic possibilities in oncology over...
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Real-world prospective analysis of treatment patterns in durvalumab maintenance after chemoradiotherapy in unresectable, locally advanced NSCLC patients
The aim of this prospective study is to evaluate the clinical use and real-world efficacy of durvalumab maintenance treatment after chemoradiotherapy...
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Immune Response Evaluation and Treatment with Immune Checkpoint Inhibitors Beyond Clinical Progression: Response Assessments for Cancer Immunotherapy
Purpose of ReviewThis review provides a comprehensive assessment of recent literature reports describing atypical response patterns observed with...
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Immune checkpoint inhibitor using in cases with gestational trophoblastic diseases
Gestational trophoblastic neoplasias (GTNs) are chemosensitive disorders with very high cure rates. However, individuals with chemoresistant diseases...