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Novel indices representing heterogeneous distributions of myocardial perfusion imaging
IntroductionHeterogeneous distribution in myocardial perfusion images (MPI) obtained by scintigraphy is often observed in cardiac diseases with...
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An exploration of gastric cancer with heterogeneous mismatch repair status
Survival benefits or symptom alleviation from immune checkpoint blockade therapy can be seen in microsatellite instability-high (MSI-H) cases....
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Heterogeneous expression of ARID1A in colorectal cancer indicates distinguish immune landscape and efficacy of immunotherapy
ObjectiveAT-rich interaction domain 1A (ARID1A) mutant tumors show active anti-tumor immune response, which is the potential indication of...
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Prognosis of a Heterogeneous TRG Pathological Response to Neoadjuvant Chemotherapy in Patients who Undergo Resection for Colorectal Liver Metastases
BackgroundOptimal management of colorectal liver metastasis (CRLM) is based on a combination of chemotherapy and surgical resection. The tumor...
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Exploring potential circRNA biomarkers for cancers based on double-line heterogeneous graph representation learning
BackgroundCompared with the time-consuming and labor-intensive for biological validation in vitro or in vivo, the computational models can provide...
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Analysis of heterogeneous growth changes in longitudinal height of children
BackgroundThere have been methodologies developed for a wide range of longitudinal data types; nevertheless, the conventional growth study is...
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A Tutorial Introduction to Heterogeneous Treatment Effect Estimation with Meta-learners
Psychotherapy has been proven to be effective on average, though patients respond very differently to treatment. Understanding which characteristics...
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Surgically resected lung adenocarcinoma: do heterogeneous GGNs and part-solid nodules on thin-section CT show different prognosis?
PurposeThis study aimed to evaluate the clinical courses of patients with surgically resected stage IA pulmonary adenocarcinoma (Ad) who exhibited...
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Understanding the relationship between stay-at-home measures and vaccine shortages: a conventional, heterogeneous, and fractional dynamic approach
In light of the global prevalence of a highly contagious respiratory disease, this study presents a novel approach to address the pressing and...
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Heterogeneous effects of cytotoxic chemotherapies for platinum-resistant ovarian cancer
BackgroundSingle-agent chemotherapy with or without bevacizumab (Bev) is a standard therapy for platinum-resistant ovarian cancer (PR-OC). However,...
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Heterogeneous effects of hospital competition on inpatient quality: an analysis of five common diseases in China
BackgroundMany countries has introduced pro-competition policies in the delivery of healthcare to improve medical quality, including China. With the...
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Symptom-based stratification algorithm for heterogeneous symptoms of dry eye disease: a feasibility study
Background/objectiveTo test the feasibility of a dry eye disease (DED) symptom stratification algorithm previously established for the general...
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Exploring heterogeneous expression of beta-actin (ACTB) in bladder cancer by producing a monoclonal antibody 6D6
BackgroundTo predict outcomes and identify potential therapeutic targets for cancers, it is critical to find novel specific biomarkers. The objective...
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Health insurance fraud detection by using an attributed heterogeneous information network with a hierarchical attention mechanism
BackgroundWith the rapid growth of healthcare services, health insurance fraud detection has become an important measure to ensure efficient use of...
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Evaluating the heterogeneous effect of extended culture to blastocyst transfer on the implantation outcome via causal inference in fresh ICSI cycles
PurposeIn IVF treatments, extended culture to single blastocyst transfer is the recommended protocol over cleavage-stage transfer. However,...
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Distributed learning for heterogeneous clinical data with application to integrating COVID-19 data across 230 sites
Integrating real-world data (RWD) from several clinical sites offers great opportunities to improve estimation with a more general population...
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Columnar Cell Thyroid Carcinoma: A Heterogeneous Entity Demonstrating Overlap Between Papillary Thyroid Carcinoma and Follicular Neoplasms
BackgroundColumnar cell papillary thyroid carcinoma (CC-PTC) is a morphologic subtype of papillary thyroid carcinoma with a variable prognosis. It is...
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Heterogeneous circulating tumor cells correlate with responses to neoadjuvant chemotherapy and prognosis in patients with locally advanced breast cancer
Neoadjuvant chemotherapy (NCT) is the standard treatment for patients with locally advanced breast cancer (LABC). The predictive value of...
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The diagnostic accuracy of photopic negative responses evoked by broadband and chromatic stimuli in a clinically heterogeneous population
PurposeTo compare the diagnostic accuracy of the photopic negative response (PhNR) elicited by red-blue (RB) and white-white (WW) stimuli, for...
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Immunohistochemical and molecular profiles of heterogeneous components of metaplastic breast cancer: a squamous cell carcinomatous component was distinct from a spindle cell carcinomatous component
Metaplastic breast carcinoma (MBC), a category of breast cancer, includes different histological types, which are occasionally mixed and...