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Pharmacological Management of Atypical Hemolytic Uremic Syndrome in Pediatric Patients: Current and Future
Atypical hemolytic uremic syndrome is a thrombotic microangiopathy characterized by hemolysis, thrombocytopenia, and acute kidney injury, usually...
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Clostridium septicum infection complicating Hemolytic-Uremic Syndrome: a case report and review of the literature
Clostridium septicum ( C. septicum ) is a zoonotic bacillus found in 2.8% of healthy human stools. In humans, it can cause serious infections such as...
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Anti-factor B antibodies in atypical hemolytic uremic syndrome
BackgroundThe etiology of atypical hemolytic uremic syndrome (aHUS) is unknown in 30–40% of patients. Anti-factor B (FB) antibodies are reported in...
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Autonomic activity and cardiovascular system risk assessment in pediatric patients with hemolytic uremic syndrome
In pediatric patients with hemolytic uremic syndrome (HUS), cardiac involvement and autonomic nervous system function can be evaluated by a...
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Veno-venous extracorporeal membrane oxygenation in managing acute respiratory distress syndrome associated with hemolytic uremic syndrome and septic shock: a case report
Veno-venous extracorporeal membrane oxygenation (VV-ECMO) is a rescue therapy for severe respiratory failure in which conventional mechanical...
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Adolescence-onset atypical hemolytic uremic syndrome: is it different from infant-onset?
BackgroundAtypical hemolytic uremic syndrome (aHUS) is a rare, mostly complement-mediated thrombotic microangiopathy. The majority of patients are...
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Heparin-induced thrombocytopenia following Shiga-toxin-associated hemolytic uremic syndrome: a case report
BackgroundUp to 50% of cases of Shiga-toxin-producing Escherichia coli hemolytic uremic syndrome occur in adults, and the clinical presentation is...
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Systemic lupus erythematosus presenting with atypical hemolytic uremic syndrome: a case report and review of the literature
Systemic lupus erythematosus (SLE) can present with a diverse array of hematologic manifestations, among which atypical hemolytic uremic syndrome...
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Anti-CFH-associated hemolytic uremic syndrome: do we still need plasma exchange?
BackgroundBetween 5 and 50% of atypical hemolytic uremic syndrome (aHUS) cases in children are caused by autoantibodies against complement factor H...
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Duration of prodromal phase and severity of hemolytic uremic syndrome
BackgroundSome data have recognized an association between shorter prodromal phase and severe episode of Shiga toxin-producing Escherichia coli -relat...
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Development and pilot implementation of Iranian Hemolytic Uremic Syndrome Registry
BackgroundPatients with Hemolytic Uremic Syndrome (HUS) face late diagnosis and lack of appropriate treatment because of a lack of knowledge and...
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Eculizumab use in patients with pneumococcal-associated hemolytic uremic syndrome and kidney outcomes
BackgroundStreptococcus pneumoniae -associated hemolytic uremic syndrome (P-HUS) is a rare and severe disease. Only a few reports have been published...
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Acute pancreatitis complicated by hemolytic uremic syndrome: a pediatric case
BackgroundHemolytic uremic syndrome (HUS) is characterized by microangiopathic hemolytic anemia (MAHA), thrombocytopenia, and acute kidney injury....
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Gastrointestinal involvement in STEC-associated hemolytic uremic syndrome: 10 years in a pediatric center
BackgroundThe gastrointestinal (GI) tract represents one of the main targets of typical hemolytic uremic syndrome (HUS) in children. In this...
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Predictors of acute ischemic cerebral lesions in immune-mediated thrombotic thrombocytopenic purpura and hemolytic uremic syndrome
BackgroundThe immune form of thrombotic thrombocytopenic purpura (iTTP) and the hemolytic and uremic syndrome (HUS) are two major forms of thrombotic...
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Abbreviated protocol of plasma exchanges for patients with anti-factor H associated hemolytic uremic syndrome
BackgroundPlasma exchanges (PEX) and immunosuppression are the cornerstone of management of anti-factor H (FH) antibody-associated atypical hemolytic...
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Cerebral microstructural changes in children suffering from hemolytic uremic syndrome
To evaluate microstructural cerebral changes in children suffering from typical hemolytic uremic syndrome (HUS) based on apparent diffusion...
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Outcome of atypical hemolytic uremic syndrome: role of triggers and complement abnormalities in the response to C5 inhibition
BackgroundAtypical-hemolytic uremic syndrome (aHUS) is a rare thrombotic microangiopathy often due to uncontrolled complement activation,...
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Volume expansion mitigates Shiga toxin-producing E. coli-hemolytic uremic syndrome in children
BackgroundShiga toxin-producing E. coli -hemolytic uremic syndrome (STEC-HUS) is associated with high morbidity and relevant mortality. Previous...
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Shiga toxin-producing Escherichia coli-associated hemolytic uremic syndrome with recurrent acute cholecystitis: a case report
Shiga toxin-producing Escherichia coli -associated hemolytic uremic syndrome (STEC-HUS) can induce life-threatening complications, including acute...
