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Protective Effects of Different Hypothermal Preservation Solutions on Structure and Function of Isolated Rat Arteries
ObjectiveWith the increasing application of vascular reconstruction in surgical procedures, allogeneic vessels are becoming more popular in clinical...
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Histidine–tryptophan–ketoglutarate solution versus multidose cardioplegia for myocardial protection in cardiac surgeries: a systematic review and meta-analysis
BackgroundSurgical procedures in the heart requires protection of the heart from ischemia–reperfusion injury. Cardioplegia is the primary myocardial...
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Custodiol HTK versus Plegisol: in-vitro comparison with the use of immature (H9C2) and mature (HCM) cardiomyocytes cultures
BackgroundAlthough cardioplegia is used since the ‘70s of the last century, debate on cardioprotection during cardio-surgical procedures is still...
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TJ-M2010-5 Attenuates Severe Myocardial Ischemia/Reperfusion Injury in Heart Transplantation by Inhibiting MyD88 Homodimerization In Vivo
Survival of transplanted hearts is often limited by cold ischemia time. Here, we assessed the effects of the small molecular compound TJ-M2010-5 on...
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Myocardial protection with histidine-tryptophan-ketoglutarate solution in comparison with hypothermic hyperkalemic blood solution in the correction of acyanotic congenital heart diseases
BackgroundIntraoperative myocardial preservation is essential in pediatric cardiac surgeries. The combination of hypothermia and hyperkalemic...
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Del Nido versus HTK cardioplegia for myocardial protection during adult complex valve surgery: a retrospective study
BackgroundHistidine-tryptophan-ketoglutarate (HTK) and del Nido (DN) cardioplegia are intracellular-type and extracellular-type solution...
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Effect of different cardioprotective methods on extracorporeal circulation in fetal sheep: a randomized controlled trial
BackgroundCongenital heart disease is a leading cause of death in newborns and infants. The feasibility of fetal cardiac surgery is linked to...
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Antiarrhythmic effect of sevoflurane as an additive to HTK solution on reperfusion arrhythmias induced by hypothermia and ischaemia is associated with the phosphorylation of connexin 43 at serine 368
BackgroundReperfusion ventricular arrhythmia (RA) associated with hypothermic ischaemic storage is increasingly recognized as a substantial...
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Single-Dose St. Thomas Versus Custodiol® Cardioplegia for Right Mini-thoracotomy Mitral Valve Surgery
ObjectiveCustodiol® and St. Thomas cardioplegia are widely employed in mini-thoracotomy mitral valve (MV) operations. One-dose of the former provides...
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Modified cardiopulmonary bypass with low priming volume for blood conservation in cardiac valve replacement surgery
BackgroundThe adverse effects of cardiopulmonary bypass during open cardiac surgery, including hemodilution, seem to be inevitable, especially for...
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Custodiol versus blood cardioplegia in pediatric cardiac surgery: a randomized controlled trial
BackgroundBlood-based cardioplegia is the standard myocardial protection strategy in pediatric cardiac surgery. Custadiol...
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Atrial approaches in mitral valve surgery: a propensity analysis of differences in the incidence of clinically relevant adverse effects
BackgroundThe lack of evidence on complications using mitral valve approaches leaves the choice of risk exposure to the surgeon’s preference, based...
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Functional survival of rat pituitary gland in hypothermic storage for pituitary transplantation
PurposeDeteriorated pituitary function can lead to serious complications that might need lifelong hormone replacement therapy. However, long-term...
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Noninvasive measurement of 13Carbon turnover for evaluation of porcine renal grafts during ex vivo machine perfusion
BackgroundKidney transplantation suffers from a shortage of donor organs. Despite this, a lot of grafts are discarded due to inadequate quality. As...
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Procedures and technical considerations of robotic-assisted human uterus transplantation
BackgroundUterus transplantation is the only treatment for absolute uterine factor infertility. Complex vascular anatomy, long operation time, and...
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Comparison of surgical and conservative treatment outcomes for type a aortic intramural hematoma
ObjectiveThis study aimed to compare hospital and long-term clinical outcomes associated with various treatment methods for Stanford A type aortic...
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Efficacy of lengthening right renal veins using accompanying gonadal veins in living donor kidney transplantation
BackgroundShort harvested right renal veins (RV) are quite common in living donor kidney transplantation (KT). This technical difficulty might...
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Acute type a aortic intramural hematoma complicated with preoperative hemopericardium: early and late surgical outcome analyses
BackgroundAcute type A aortic intramural hematoma (ATAIMH) is a variant of acute type A aortic dissection (ATAAD), exhibiting an increased risk of...
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Effects of transcutaneous electrical nerve stimulation on myocardial protection in patients undergoing aortic valve replacement: a randomized clinical trial
BackgroundCardiopulmonary bypass-related myocardial ischemia-reperfusion injury is a major contributor to postoperative morbidity. Although...
