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Epigenetic associations in HPA axis genes related to bronchopulmonary dysplasia and antenatal steroids
BackgroundBronchopulmonary dysplasia (BPD), a common morbidity among very preterm infants, is associated with chronic disease and neurodevelopmental...
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The effects of IPV and mental health symptoms on HPA axis functioning during early pregnancy
Maternal HPA axis dysregulation during early pregnancy can negatively affect maternal functioning. However, findings are mixed regarding how intimate...
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Prenatal stress modulates HPA axis homeostasis of offspring through dentate TERT independently of glucocorticoids receptor
In response to stressful events, the hypothalamic-pituitary-adrenal (HPA) axis is activated, and consequently glucocorticoids are released by the...
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PPARα suppresses low-intensity-noise-induced body weight gain in mice: the activated HPA axis plays an critical role
BackgroundAs the second most risky environmental pollution, noise imposes threats to human health. Exposure to high-intensity noise causes hearing...
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From childhood adversity to latent stress vulnerability in adulthood: the mediating roles of sleep disturbances and HPA axis dysfunction
Childhood adversity is a prominent predisposing risk factor for latent stress vulnerability, expressed as an elevated likelihood of develo**...
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Network analysis of comorbid depression, suicidality and biomarkers on HPA axis among mood disorder patients to psychiatric emergency services
Rapid assessment and intervention of suicide risk are common and challenging in psychiatric emergency departments (PED). It is unclear whether...
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Alterations of monoamine neurotransmitters, HPA-axis hormones, and inflammation cytokines in reserpine-induced hyperalgesia and depression comorbidity rat model
BackgroundPain and depression often occur simultaneously, but the mechanism of this condition is still unclear.
MethodsThe aim of this study was to...
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Localized alopecia and suppression of hypothalamic-pituitary-adrenal (HPA) axis in dogs following treatment with difluprednate 0.05% ophthalmic emulsion (Durezol®)
BackgroundDespite the common use of topical ophthalmic corticosteroids in dogs, detailed reports on systemic and dermatologic adverse effects are...
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Investigation of the Hypothalamo-pituitary-adrenal (HPA) axis: a contemporary synthesis
The hypothalamo-pituitary-adrenal (HPA) axis is one of the main components of the stress system. Maintenance of normal physiological events, which...
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Acute stress responses of autonomous nervous system, HPA axis, and inflammatory system in posttraumatic stress disorder
Posttraumatic stress disorder (PTSD) does not only have direct consequences for well-being, but it also comes with a significant risk for severe...
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Impact of maternal trauma-related psychopathology and life stress on HPA axis stress response
To understand and curb intergenerational transmission of stress-related disorder, it is important to identify how trauma-related psychopathology in...
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The recovery time of hypothalamic-pituitary-adrenal axis after curative surgery in Cushing’s disease and its related factor
PurposePatients with Cushing’s disease (CD) experienced transient central adrenal insufficiency (CAI) after successful surgery. However, the reported...
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Sex-specific interactions between stress axis and redox balance are associated with internalizing symptoms and brain white matter microstructure in adolescents
Adolescence is marked by the maturation of systems involved in emotional regulation and by an increased risk for internalizing disorders...
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Microbiota-Gut-Brain Axis in Psychiatry: Focus on Depressive Disorders
Purpose of ReviewGut microbiota contribute to several physiological processes in the host. The composition of the gut microbiome is associated with...
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Effects of Lactococcus lactis subsp. cremoris YRC3780 daily intake on the HPA axis response to acute psychological stress in healthy Japanese men
BackgroundLactococcus lactis subsp. cremoris (YRC3780), which is isolated from kefir, has been associated with anti-allergic effects in humans....
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Effect of Long-term Inhaled Corticosteroids on the Hypothalamic-Pituitary-Adrenal Axis in Children with Asthma
ObjectivesTo assess the effect of the long-term use of inhaled corticosteroids (ICS) on the hypothalamic-pituitary-adrenal (HPA) axis.
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Effects of very low-calorie ketogenic diet on hypothalamic–pituitary–adrenal axis and renin–angiotensin–aldosterone system
BackgroundThe hypothalamic–pituitary–adrenal (HPA) axis is a neuroendocrine system involved in controlling stress responses in humans under...
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Parameterizing Toxic Stress in Early Childhood: Maternal Depression, Maltreatment, and HPA-Axis Variation in a Pilot Intervention Study
Adverse experiences superseding a child’s capacity to sustain regulation of emotion and adaptive function are theorized to constitute “toxic...
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Metformin effectively restores the HPA axis function in diet-induced obese rats
IntroductionThe hypothalamo-pituitary-adrenal (HPA) axis is perturbed in obesity. We previously reported presence of leptin resistance in the...
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P11 deficiency increases stress reactivity along with HPA axis and autonomic hyperresponsiveness
Patients suffering from mood disorders and anxiety commonly exhibit hypothalamic–pituitary–adrenocortical (HPA) axis and autonomic...
