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Case history factors and audiological screening outcomes in HEU and HIV unexposed neonates at a district level hospital in Gauteng, South Africa
While progress has been made in reducing vertical Mother to Child Transmission (MTCT) of HIV, limited research exists on the health needs of...
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Clinical and immunological outcomes of HIV-exposed uninfected and HIV-unexposed uninfected children in the first 24 months of life in Western Kenya
BackgroundPrevious studies show increased morbidity in children who are HIV-exposed but uninfected (HEU) compared to children who are HIV-unexposed...
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Immunoglobulin G passive transfer from mothers to infants: total IgG, IgG subclasses and specific antipneumococcal IgG in 6-week Malawian infants exposed or unexposed to HIV
BackgroundThe impaired transplacental passage of IgG from mothers living with HIV to their infants could be one of the causes of the high...
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Growth patterns and clinical outcomes in association with breastfeeding duration in HIV exposed and unexposed infants: a cohort study in KwaZulu Natal, South Africa
BackgroundExclusive breastfeeding for 6 months and breastfeeding with complementary feeds until 12 months for HIV exposed and uninfected (HEU)...
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Caries experience and oral health related quality of life in a cohort of Ugandan HIV-1 exposed uninfected children compared with a matched cohort of HIV unexposed uninfected children
BackgroundVery few studies consider the oral health status and quality of life in HIV-1 exposed uninfected (HEU) children. The aim of this study was...
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Short-term outcomes of HIV-exposed and HIV-unexposed preterm, very low birthweight neonates: a longitudinal, hospital-based study
ObjectiveTo compare short-term outcomes of very low birthweight (VBLW, <1500 g) neonates by maternal HIV status.
DesignRetrospective hospital-based...
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Neurobehavioural challenges experienced by HIV exposed infants: a study in South Africa
BackgroundThe newborn infant is a complexly organized, competent being, who plays an active role in sha** their environment through their...
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Association of in utero HIV exposure with child brain structure and language development: a South African birth cohort study
BackgroundThere is a growing population of children with in utero HIV exposure who are at risk of poor neurodevelopmental outcomes despite avoiding...
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Effects of the COVID-19 pandemic on the outcomes of HIV-exposed neonates: a Zimbabwean tertiary hospital experience
IntroductionThe COVID-19 pandemic has globally impacted health service access, delivery and resources. There are limited data regarding the impact on...
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Associations Between Social Support and Symptoms of Antenatal Depression with Infant Growth and Development Among Mothers Living with HIV in Tanzania
Children born to mothers living with HIV may experience greater risk of poor growth and development outcomes than their HIV-unexposed peers. Few...
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The effects of exposure to HIV in neonates at a referral hospital in South Africa
BackgroundFewer infants are infected with HIV through mother-to-child transmission, making HIV-exposed but uninfected (HEU) infants a growing...
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Effectiveness of a 6-Month Isoniazid on Prevention of Incident Tuberculosis Among People Living with HIV in Eritrea: A Retrospective Cohort Study
IntroductionA 6-month isoniazid as tuberculosis preventive therapy (TPT) for people living with HIV (PLHIV) was nationally introduced in Eritrea in...
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Correlates of health-related quality of life in primary caregivers of perinatally HIV infected and HIV exposed uninfected adolescents at the Kenyan Coast
BackgroundMothers and other primary caregivers play a crucial role in looking after perinatally HIV infected, and HIV exposed uninfected adolescents...
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Increased risk of group B streptococcal sepsis and meningitis in HIV-exposed uninfected infants in a high-income country
The purpose of this study is to compare group B Streptococcus (GBS) infection incidence in HIV-exposed uninfected (HEU) and HIV-unexposed (HU)...
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Antenatal hepatitis B virus sero-prevalence, risk factors, pregnancy outcomes and vertical transmission rate within 24 months after birth in a high HIV prevalence setting
BackgroundDespite the availability of an effective vaccine, chronic hepatitis B virus (HBV) infections remain a major cause of liver cirrhosis and...
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Bifidobacterium infantis supplementation versus placebo in early life to improve immunity in infants exposed to HIV: a protocol for a randomized trial
IntroductionInfants who are born from mothers with HIV (infants who are HIV exposed but uninfected; iHEU) are at higher risk of morbidity and display...
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Distinct cord blood C-peptide, adipokine, and lipidomic signatures by in utero HIV exposure
BackgroundEarly-life metabolic derangements in HIV-exposed uninfected (HEU) infants have been reported.
MethodsPregnant women with HIV and...
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Growth patterns of infants with in- utero HIV and ARV exposure in Cape Town, South Africa and Lusaka, Zambia
BackgroundInfants born HIV-exposed yet remain uninfected (HEU) are at increased risk of poorer growth and health compared to infants born...
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Lower birth weight-for-age and length-for-age z-scores in infants with in-utero HIV and ART exposure: a prospective study in Cape Town, South Africa
BackgroundSuccessful scale-up of antiretroviral therapy (ART) during pregnancy has minimized infant HIV acquisition, and over 1 million infants are...
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Flexible modelling of risk factors on the incidence of pneumonia in young children in South Africa using piece-wise exponential additive mixed modelling
IntroductionRecurrent episodes of pneumonia are frequently modeled using extensions of the Cox proportional hazards model with the underlying...
