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Lymphome und andere hämatologische Neoplasien im Hoden
BackgroundThe testis may be infiltrated by hematological neoplasias. However, only few entities present as primary testicular diseases.
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Bedeutung der klonalen Hämatopoese für hämatologische Neoplasien
BackgroundClonal hematopoiesis of indeterminate potential (CHIP) is a fairly newly described phenomenon characterized by myeloid cancer-associated...
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Myeloische/lymphatische Neoplasien mit Eosinophilie und Tyrosinkinase-Fusionsgenen
Myeloid/lymphoid neoplasm with eosinophilia and tyrosine kinase fusion genes (MLN-TK) include hematological neoplasms with rearrangements/fusion...
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Einfluss der klonalen Hämatopoese auf nicht-hämatologische Erkrankungen und Alterungsprozesse
The occurrence of clonal hematopoiesis, caused by acquired somatic mutations of leukemia-associated genes in blood stem cells is very common in the...
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Hauterkrankungen als Hinweis auf Neoplasien
In contrast to the obligatory paraneoplasias, which are usually rare, diseases such as Sweet’s syndrome, thrombophlebitis or herpes zoster are more...
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Hämatologische Neoplasien als Differenzialdiagnosen von Weichgewebstumoren
BackgroundSeveral hematological malignancies might morphologically present as differential diagnoses of sarcomas.
ObjectivesTo illustrate entities...
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Empfohlene Diagnostik bei Pruritus auf primär unveränderter Haut
BackgroundChronic pruritus affecting primary non-lesional skin (CPNL) manifests as a common symptom across a spectrum of diseases spanning various...
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Klonale Hämatopoese und Knochenmarkinfiltration bei Patienten mit einem nodalen Lymphom der T-follikulären Helferzellen
T‑follicular helper (TFH) cell lymphoma (TFHL) is a lymphoma of mature T cells with phenotypic characteristics and gene expression signature of TFH...
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CUP-Syndrom – Diagnostik aus Sicht der Pathologie
ProblemHistologic and immunohistologic workup of tumor material from metastases of a previously unknown primary tumor is important for identifying...
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Sekundäre Vaskulitiden
Vasculitides that occur in association with underlying primary diseases are called secondary vasculitides. In the diverse differential diagnostics of...
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Entitätsübergreifende Qualitätsindikatoren und Kennzahlen: Ergebnisse und Entwicklungen
BackgroundThe certification system of the German Cancer Society (DKG) is tumor entity-specific and based on S3 guidelines. Therefore, quality...
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Paraneoplastische Syndrome in der Rheumatologie
Paraneoplastic syndromes in rheumatology are a group of canonical rare rheumatic diseases with musculoskeletal involvement that occur in close...
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Karzinom unklaren Ursprungs – interdisziplinäre Therapiestruktur
BackgroundCancer of unknown primary (CUP) still represents a diagnostic and therapeutic challenge. The prognosis of CUP is poor in most cases,...
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Diagnostik bei unklaren Zytopenien – wie und wann suchen wir nach klonaler Hämatopoese?
BackgroundMany studies have analyzed the clinical significance of clonal hematopoiesis. The collected data lead to the conclusion that in defined...
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WHO-Klassifikation 2022 chronischer myeloproliferativer Erkrankungen
BackgroundHuman neoplasms of various organ systems are being hierarchically cataloged by the World Health Organization (WHO) in a unified relational...
