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Estimated glomerular filtration rate in observational and interventional studies in chronic kidney disease
Estimated glomerular filtration rate is considered the principal measure of kidney function and, together with albuminuria, is a relevant prognostic...
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Glomerular crescents are associated with the risk of type 2 diabetic kidney disease progression: a retrospective cohort study
BackgroundDiabetic kidney disease (DKD) stands as the predominant cause of chronic kidney disease and end-stage kidney disease. Its diverse range of...
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Total flavonoids of Astragalus protects glomerular filtration barrier in diabetic kidney disease
BackgroundDiabetic kidney disease (DKD) is a prevalent complication of diabetes and the leading cause of end-stage renal disease. Recent evidence...
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Atypical anti-glomerular basement membrane disease with membranous hyperplasia: diagnostic challenges and treatment variability
This case report presents a detailed analysis of a 31-year-old male patient who presented with a complex array of clinical symptoms, including...
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The role of PCSK9 in glomerular lipid accumulation and renal injury in diabetic kidney disease
Aims/hypothesisGlomerular lipid accumulation is a defining feature of diabetic kidney disease (DKD); however, the precise underlying mechanism...
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A case report of atypical anti-glomerular basement membrane disease
BackgroundAnti-glomerular basement membrane (anti-GBM) disease is characterized by crescentic necrotizing glomerulonephritis, with linear deposits of...
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The expression of respiratory tract virus in pediatric glomerular disease: a retrospective study of 45 renal biopsy in China
BackgroundMore attention has been put on the relationship between pediatric glomerular disease and respiratory tract virus infection. Children with...
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Pubertal luteinizing hormone levels in children with chronic kidney disease and association with change in glomerular filtration rate
BackgroundChildren with chronic kidney disease (CKD) are at risk for abnormalities in pubertal development. We aimed to describe the timing of...
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Glomerular proteomic profiling of kidney biopsies with hypertensive nephropathy reveals a signature of disease progression
Hypertensive nephropathy (HN) requires a kidney biopsy as diagnostic gold-standard but histological findings are unspecific and specific prognostic...
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Underlying Mechanisms and Treatment of Hypertension in Glomerular Diseases
Purpose of ReviewThis review aims to explore the underlying mechanisms that lead to hypertension in glomerular diseases and the advancements in...
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Basement membrane defects in CD151-associated glomerular disease
BackgroundCD151 is a cell-surface molecule of the tetraspanin family. Its lateral interaction with laminin-binding integrin ɑ3β1 is important for...
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Pathology of Glomerular Diseases Atlas of Clinical Case Studies
This book provides clear understanding of morphological appearances of various glomerular lesions encountered in a wide range of diseases involving...
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Soluble urokinase plasminogen activator receptor (suPAR) and glomerular disease in children: a narrative review
BackgroundFocal segmental glomerulosclerosis (FSGS) is a chronic glomerular disease that responds poorly to treatment, with a large proportion of...
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Vitamin D supplementation in children and young adults with persistent proteinuria secondary to glomerular disease
BackgroundVitamin D deficiency is common in glomerular disease. Supplementation may be ineffective due to ongoing urinary losses of vitamin D binding...
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Therapeutic plasma exchange for anti-glomerular basement membrane disease with dialysis-dependent kidney failure without diffuse alveolar hemorrhage
BackgroundAnti-glomerular basement membrane (anti-GBM) disease is treated with immunosuppressive medications and plasma exchange. However, whether...
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Slope of the estimated glomerular filtration rate and its associated factors among individuals with chronic kidney disease in the general Japanese population
BackgroundTo suppress the incidence of end-stage kidney disease, we need to identify chronic kidney disease (CKD) patients with a high risk of rapid...
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Obesity and glomerular filtration rate
Obesity has received considerable attention in general medicine and nephrology over the last few years. This condition increases the risk of...
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Demographic distribution analysis of different glomerular diseases in Southwest China from 2008 to 2022
BackgroundEnvironmental and lifestyle factors play an etiological role in the pathogenesis of different glomerular diseases. Thus, exploring the...
