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Pregnancy-associated changes in urinary uromodulin excretion in chronic hypertension
BackgroundPregnancy involves major adaptations in renal haemodynamics, tubular, and endocrine functions. Hypertensive disorders of pregnancy are a...
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Urinary excretion kinetics of [177Lu]Lu-PSMA-617
IntroductionFor the implementation of suitable radiation safety measures in [ 177 Lu]Lu-PSMA-617 therapy, additional insight into excretion kinetics...
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Spot urinary sodium in CKD patients: correlation with 24h-excretion and evaluation of commonly used prediction equations
BackgroundSalt intake in CKD patients can affect cardiovascular risk and kidney disease progression. Twenty-four hour (24h) urine collections are...
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Can we Predict Drug Excretion into Saliva? A Systematic Review and Analysis of Physicochemical Properties
Background and ObjectivesSaliva is a patient-friendly matrix for therapeutic drug monitoring (TDM) but is infrequently used in routine care. This is...
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Development of a novel nomogram for predicting delayed methotrexate excretion following high-dose methotrexate in adult patients with hematologic malignancies
PurposeHigh-dose methotrexate (HDMTX) is integral in treating hematologic malignancies but carries risks of severe toxicities due to prolonged MTX...
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Periodicity of Ascaridia galli egg excretion in experimentally infected chicken in the Philippines
The periodicity of parasite egg excretion refers to variations in the number of eggs produced across time, with significant implications in...
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Alteration of the maximal renal water excretion capacity with kidney function and age in human
PurposeThe kidney’s capability to concentrate and dilute urine is crucial to maintaining body fluid compartments and plasma osmolality. Advanced age...
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Association between sodium and potassium excretion estimated from spot urine and socioeconomic status among primary school children and their mothers in Okinawa, Japan
Hypertension is the greatest and the most preventable risk factor for cardiovascular disease. Excessive sodium (Na) intake and insufficient potassium...
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Pseudo-nephropathy and hyper-excretion of urinary C-peptide: an overlooked adverse effect of an angiotensin receptor–neprilysin inhibitor (ARNI)
Sacubitril/valsartan, which is a combined angiotensin receptor–neprilysin inhibitor (ARNI), is used for the treatment of chronic heart failure and...
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Determinants on urinary excretion of oxalate and other key factors related to urolithiasis among patients with chronic kidney disease: a single center study
PurposeUrolithiasis is a known risk factor for chronic kidney disease (CKD). However, how CKD might affect the risk of incidence of urolithiasis is...
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Association of urinary calcium excretion with chronic kidney disease in patients with type 2 diabetes
PurposeHerein, we investigated the correlation between urinary calcium excretion (UCaE) and chronic kidney disease (CKD) in patients with type 2...
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A simple assessment of the effect of strontium on the urinary excretion of calcium in Sprague Dawley rats
This study was aimed at investigating the impact of varying concentrations of strontium (Sr) on calcium (Ca) excretion via the urine and determine...
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Estimated 24-Hour urinary sodium and potassium excretion in adults in the Northwest Region of Morocco, 2017
BackgroundExcessive sodium (Na) and insufficient potassium (K) intake contribute to a high risk of cardiovascular events. Morocco lacks data on...
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Urinary catecholamine excretion, cardiovascular variability, and outcomes in tetanus
Severe tetanus is characterized by muscle spasm and cardiovascular system disturbance. The pathophysiology of muscle spasm is relatively well...
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The insoluble excretion of multi-matrix system mesalazine preparations in patients with ulcerative colitis
BackgroundMulti-matrix mesalazine (MMX) is an important treatment for ulcerative colitis (UC); however, it is often excreted intact, which increases...
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Excretion of glucose analogue with SGLT2 affinity predicts response effectiveness to sodium glucose transporter 2 inhibitors in patients with type 2 diabetes mellitus
PurposeSodium-glucose cotransporter 2 inhibitor (SGLT2i) regulation, developed as treatment for patients with type 2 diabetes, can be imaged with the...
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Being overweight worsens the relationship between urinary sodium excretion and albuminuria: the Wakuya study
Background/objectives(Micro)albuminuria (a manifestation of renal microvascular damage) is an independent predictor of mortality risk, even when the...
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Circadian rhythm of water and solute excretion in nocturnal enuresis
BackgroundNocturnal polyuria (NP) due to a suppressed vasopressin circadian rhythm is a well-documented pathogenetic mechanism in enuresis, mainly...
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Genetic deletion of hepatic NCOR1 protects from atherosclerosis by promoting alternative bile acid-metabolism and sterol excretion
BackgroundThe nuclear receptor corepressor 1 (NCOR1) plays an important role in the regulation of gene expression in immunometabolic conditions by...
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Cinacalcet increases renal calcium excretion in PTHrP-mediated hypercalcemia: a case report
BackgroundIn the acute setting, PTH-independent hypercalcemia is typically treated with anti-resorptive agents such as zoledronic acid or denosumab....