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Envisioning the future of colorectal surgery: preclinical assessment and detailed description of an endoluminal robotic system (ColubrisMX ELS)
BackgroundThe EndoLuminal Surgical System (ELS) is an emerging non-linear robotic system specifically designed for transanal surgery that allows for...
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Early life stress is associated with greater negative emotionality and peripheral inflammation in alcohol use disorder
Early life stress (ELS) increases risk for psychiatric illness, including alcohol use disorder (AUD). Researchers have hypothesized that individuals...
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Prognostische Aussagekraft der ELS-Klassifikation bei der Beurteilung laryngotrachealer Stenosen im Kindesalter
BackgroundIn 2015, the European Laryngological Society (ELS) published a consensus paper in which a new classification system for laryngotracheal...
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Early life stress moderates the relation between systemic inflammation and neural activation to reward in adolescents both cross-sectionally and longitudinally
Elevated levels of systemic inflammation are associated with altered reward-related brain function in ventral striatal areas of the brain like the...
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Early life stress and body-mass-index modulate brain connectivity in alcohol use disorder
Early life stress (ELS) significantly increases susceptibility to alcohol use disorder (AUD) by affecting the interplay between the executive and the...
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Perceptual learning deficits mediated by somatostatin releasing inhibitory interneurons of olfactory bulb in an early life stress mouse model
Early life adversity (ELA) causes aberrant functioning of neural circuits affecting the health of an individual. While ELA-induced behavioural...
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Early-life stress lastingly impacts microglial transcriptome and function under basal and immune-challenged conditions
Early-life stress (ELS) leads to increased vulnerability to psychiatric disorders including depression later in life. Neuroinflammatory processes...
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The causal involvement of the BDNF-TrkB pathway in dentate gyrus in early-life stress-induced cognitive deficits in male mice
Cognitive dysfunction is a significant, untreated clinical need in patients with psychiatric disorders, for which preclinical studies are needed to...
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Dissecting early life stress-induced adolescent depression through epigenomic approach
Early life stress (ELS), such as abuse and neglect during childhood, can lead to psychiatric disorders in later life. Previous studies have suggested...
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Early life stress predicts trajectories of emotional problems and hippocampal volume in adolescence
Exposure to early life stress (ELS) has been consistently associated with adverse emotional and neural consequences in youth. The development of...
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Early-life stress biases responding to negative feedback and increases amygdala volume and vulnerability to later-life stress
Early-life stress (ELS) or adversity, particularly in the form of childhood neglect and abuse, is associated with poor mental and physical health...
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Preoperative mechanical bowel preparation using conventional versus hyperosmolar polyethylene glycol-electrolyte lavage solution before laparoscopic resection for colorectal cancer (TLUMP test): a phase III, multicenter randomized controlled non-inferiority trial
BackgroundA hyperosmolar ascorbic acid-enriched polyethylene glycol-electrolyte (ASC-PEG) lavage solution ensures excellent bowel preparation before...
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Early life stress in male mice blunts responsiveness in a translationally-relevant reward task
Early-life stress (ELS) leaves signatures upon the brain that persist throughout the lifespan and increase the risk of psychiatric illnesses...
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Incidence, Characteristics, and Cost of Eyelid Lacerations in the United States from 2006 to 2014
IntroductionTo report the incidence, demographics, and cost of eyelid lacerations (ELs) in the USA.
MethodsThe Nationwide Emergency Department...
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Association between maltreatment, hair cortisol concentration, positive parent–child interaction, and psychosocial outcomes in Chinese preschool children
Children now are facing an increasing risk of early life stress (ELS), which leads to detrimental psychosocial outcomes. Behavior studies suggested...
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Endolymphatic space is age-dependent
Knowledge of the physiological endolymphatic space (ELS) is necessary to estimate endolymphatic hydrops (ELH) in patients with vestibulocochlear...
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Oxytocin as an adolescent treatment for methamphetamine addiction after early life stress in male and female rats
Early life stress (ELS) is associated with perturbed neural development and augmented vulnerability to mental health disorders, including addiction....
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Cell-type-specific epigenetic effects of early life stress on the brain
Early life stress (ELS) induces long-term phenotypic adaptations that contribute to increased vulnerability to a host of neuropsychiatric disorders....
