Search
Search Results
-
A Multi-method Exploratory Evaluation of a Service Designed to Improve Medication Safety for Patients with Monitored Dosage Systems Following Hospital Discharge
Background and ObjectiveMedication safety problems are common post-hospital discharge, and an important global healthcare improvement target. The...
-
Medication dosage calculation among nursing students: does digital technology make a difference? A literature review
BackgroundPatient safety is a major part of nursing care and following patients’ medication orders is considered one of the greatest responsibilities...
-
Consumer expectations, drug effects, price and purity of heroin and cocaine purchased at drug consumption rooms
BackgroundDrug consumption rooms offer heroin and cocaine consumers a secure and hygienic environment including medical and social guidance. Despite...
-
Where do nursing students make mistakes when calculating drug doses? A retrospective study
BackgroundResearch internationally shows that nursing students find dosage calculation difficult. Identifying the specific aspects of dose...
-
Dose Nomogram of Individualization of the Initial Follicle-Stimulating Hormone Dosage for Patients with Polycystic Ovary Syndrome Undergoing IVF/ICSI with the GnRH-Ant Protocol: A Retrospective Cohort Study
IntroductionFor high responders with polycystic ovary syndrome (PCOS), there is no clear recommendation for the initial follicle-stimulating hormone...
-
Drug dosing in children with obesity: a narrative updated review
Childhood obesity and its associated comorbidities are highly prevalent diseases that may add to any other possible health problem commonly affecting...
-
Drug–Drug Interaction Studies of Esmethadone (REL-1017) Involving CYP3A4- and CYP2D6-Mediated Metabolism
Background and ObjectiveEsmethadone (dextromethadone; d-methadone; S-methadone (+)-methadone; REL-1017) is the opioid inactive dextro-isomer of...
-
Use of Machine Learning for Dosage Individualization of Vancomycin in Neonates
Background and ObjectiveHigh variability in vancomycin exposure in neonates requires advanced individualized dosing regimens. Achieving steady-state...
-
Can Mechanistic Static Models for Drug-Drug Interactions Support Regulatory Filing for Study Waivers and Label Recommendations?
Background and ObjectiveMechanistic static and dynamic physiologically based pharmacokinetic models are used in clinical drug development to assess...
-
Drug stewardship in chronic kidney disease to achieve effective and safe medication use
People living with chronic kidney disease (CKD) often experience multimorbidity and require polypharmacy. Kidney dysfunction can also alter the...
-
The epidemiology of drug-related hospital admissions in paediatrics – a systematic review
BackgroundDespite previous efforts, medication safety in paediatrics remains a major concern. To inform improvement strategies and further research...
-
Adverse Drug Reactions to Opioids: A Study in a National Pharmacovigilance Database
IntroductionOpioids are commonly used as analgesics; however, like any medicine, they can produce adverse drug reactions (ADRs), including nausea,...
-
Financial impact of medication reviews by clinical pharmacists to reduce in-hospital adverse drug events: a return-on-investment analysis
BackgroundAdverse drug events contribute to rising health care costs. Clinical pharmacists can reduce their risks by identifying and solving...
-
Drug Use Prevalence and Age of First Use in Sexual Minority Men Compared to General Population Men in Spain
The aim of this study was to compare the prevalence of use of ten drugs or groups of drugs and the mean age of onset of drug use among sexual...
-
Niosomes: a novel targeted drug delivery system for cancer
Recently, nanotechnology is involved in various fields of science, of which medicine is one of the most obvious. The use of nanoparticles in the...
-
Therapeutic drug monitoring in childhood idiopathic nephrotic syndrome: a state of the art review
Immunosuppressants are commonly used as steroid-sparing agents in childhood idiopathic nephrotic syndrome (NS) to induce and sustain remissions....
-
Mechanisms and Clinical Significance of Pharmacokinetic Drug Interactions Mediated by FDA and EMA-approved Hepatitis C Direct-Acting Antiviral Agents
The treatment of patients infected with the hepatitis C virus (HCV) has been revolutionised by the development of direct-acting antiviral agents...
-
Fluoropyrimidine usage in cases with hyperammonemia: real-world data study using the Japanese Adverse Drug Event Report (JADER) database
PurposeFluoropyrimidines are anticancer drugs and can cause hyperammonemia both intravenously and orally. Renal dysfunction may interact with...
-
Intensive care drug therapy and its potential adverse effects on blood pressure and heart rate in critically ill children
BackgroundOwing to complex treatment, critically ill children may experience alterations in their vital parameters. We investigated whether such...
-
Drug repurposing of FDA-approved anti-viral drugs via computational screening against novel 6M03 SARS-COVID-19
ObjectiveThe COVID-19 pandemic has been recognized as severe acute respiratory syndrome, one of the worst and disastrous infectious diseases in human...
