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Bystander CD8 + T cells may be involved in the acute phase of diffuse alveolar damage
Acute respiratory distress syndrome (ARDS) is a serious complication of systemic inflammatory response syndrome, and diffuse alveolar damage (DAD) is...
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Diffuse Alveolar Hemorrhage Secondary to Abciximab—a Case Report
Diffuse alveolar hemorrhage (DAH) is unusual and can be a life-threatening side effect of glycoprotein IIb/IIIa receptor antagonists like abciximab....
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Pulmonary capillaritis as a cause of lethal diffuse alveolar hemorrhage
Lethal pulmonary hemoptysis is a common finding in forensic medicine. Since hemoptysis does not necessarily occur before death and its previous...
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Proposed Pathogenesis of Diffuse Alveolar Hemorrhage in Idiopathic Pulmonary Hemosiderosis
Idiopathic pulmonary hemosiderosis (IPH) is a rare disease that causes diffuse alveolar hemorrhage (DAH). The latest data suggests an immunologic...
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Elevated plasma levels of Krebs von den Lungen-6 and geographic appearance on high-resolution computed tomography are associated with diffuse alveolar damage in autopsy cases of acute respiratory distress syndrome: a retrospective study
BackgroundAlthough diffuse alveolar damage (DAD) is a histopathological hallmark of acute respiratory distress syndrome (ARDS), its detection without...
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Alemtuzumab-associated diffuse alveolar damage – a case report
BackgroundIdentifying causes of alemtuzumab induced respiratory symptoms in Multiple Sclerosis (MS) patients is crucial.
Case presentation ... -
Metagenomic next-generation sequencing in the diagnosis of leptospirosis presenting as severe diffuse alveolar hemorrhage: a case report and literature review
BackgroundLeptospirosis is a common infectious disease in tropical and semitropical regions, and it is typically neglected. Leptospirosis-associated...
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Diffuse Alveolar Hemorrhage in Cardiac Diseases
Diffuse alveolar hemorrhage (DAH) is a rare condition with reported mortality ranging between 20 and 100%. There are many etiologies of DAH. Cardiac...
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Infection in systemic lupus erythematosus-associated diffuse alveolar hemorrhage: a potential key to improve outcomes
ObjectivesThis study aimed to investigate the clinical characteristics, outcomes, and associated factors of patients with systemic lupus...
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Diffuse alveolar hemorrhage in children with trisomy 21
BackgroundRespiratory conditions are the leading cause of hospitalization and death in children with Trisomy 21 (T21). Diffuse alveolar hemorrhage...
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Differentiation of idiopathic pulmonary hemosiderosis from rheumatologic and autoimmune diseases causing diffuse alveolar hemorrhage: establishing a diagnostic approach
This narrative review provides an overview of diffuse alveolar hemorrhage (DAH) associated with rheumatologic and autoimmune diseases and their...
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Symptomatic post COVID patients have impaired alveolar capillary membrane function and high VE/VCO2
BackgroundPost COVID-19 syndrome is characterized by several cardiorespiratory symptoms but the origin of patients’ reported symptomatology is still...
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Risk factors and outcomes of diffuse alveolar haemorrhage after allogeneic haematopoietic stem cell transplantation
Diffuse alveolar haemorrhage (DAH) is a life-threatening pulmonary complication occurring after allogeneic haematopoietic stem cell transplantation...
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RUNX1 targeting AKT3 promotes alveolar hypercoagulation and fibrinolytic inhibition in LPS induced ARDS
BackgroundAlveolar hypercoagulation and fibrinolytic inhibition are mainly responsible for massive alveolar fibrin deposition, which are closely...
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High neutrophils and low lymphocytes percentages in bronchoalveolar lavage fluid are prognostic factors of higher in-hospital mortality in diffuse alveolar hemorrhage
BackgroundDiffuse alveolar hemorrhage (DAH) is a syndrome resulting from bleeding in the microcirculation of the lung, with a poor prognosis. The...
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Increased number of pulmonary megakaryocytes in COVID-19 patients with diffuse alveolar damage: an autopsy study with clinical correlation and review of the literature
Pulmonary megakaryocytes participate in the pathogenesis of lung damage, particularly in acute lung injury. Although megakaryocytes are not mentioned...
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Ultra-low tidal volume ventilation during cardiopulmonary resuscitation shows no mitigating effect on pulmonary end-organ damage compared to standard ventilation: insights from a porcine model
ObjectiveThis study aimed to determine whether ultra-low tidal volume ventilation (ULTVV) applied during cardiopulmonary resuscitation (CPR) compared...
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Negative-pressure-related diffuse alveolar hemorrhage after monitored anesthesia care for vertebroplasty: a case report
BackgroundDiffuse alveolar hemorrhage (DAH) is a rare, life-threatening condition that can present as a spectrum of nonspecific symptoms, ranging...
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Role of mast cells in the pathogenesis of severe lung damage in COVID-19 patients
BackgroundThere is still insufficient knowledge with regard to the potential involvement of mast cells (MCs) and their mediators in the pathology of...
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Germany’s first COVID-19 deceased: a 59-year-old man presenting with diffuse alveolar damage due to SARS-CoV-2 infection
Clinical characterization of COVID-19 (Corona Virus Disease 2019) is being performed worldwide to gain insights into the pathogenesis and course of...