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An unwelcome inheritance: childhood obesity after diabetes in pregnancy
Diabetes in pregnancy affects 20 million women per year and is associated with increased risk of obesity in offspring, leading to insulin resistance...
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Associations Between Gestational Weight Gain, Gestational Diabetes, and Childhood Obesity Incidence
IntroductionExcessive maternal gestational weight gain (GWG) is strongly correlated with childhood obesity, yet how excess maternal weight gain and...
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Diabetes, life course and childhood socioeconomic conditions: an empirical assessment for Mexico
BackgroundDemographic and epidemiological dynamics characterized by lower fertility rates and longer life expectancy, as well as higher prevalence of...
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Maternal gestational diabetes mellitus and the childhood asthma in offspring: a meta-analysis
BackgroundMaternal diabetes might be related to a high risk of allergic disease in offspring. However, it remains unknown if maternal gestational...
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Pro- and anti-inflammatory cytokines are the game-changers in childhood obesity-associated metabolic disorders (diabetes and non-alcoholic fatty liver diseases)
Childhood obesity is a chronic inflammatory epidemic that affects children worldwide. Obesity affects approximately 1 in 5 children worldwide....
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In utero exposure to maternal diabetes or hypertension and childhood hypothalamic gliosis
Exposure to maternal diabetes (DM) or hypertension (HTN) during pregnancy impacts offspring metabolic health in childhood and beyond. Animal models...
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Mortality in childhood-onset type 1 diabetes mellitus with onset between 1959 and 1996: A population-based study in Hokkaido, Japan
AimTo examine the mortality rate and causes of death in childhood-onset type 1 diabetes in Japan.
MethodsFor a median 36.7 years, we followed 391...
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Childhood adversity and risk of type 2 diabetes in early adulthood: results from a population-wide cohort study of 1.2 million individuals
Aims/hypothesisTo examine whether childhood adversity is related to development of type 2 diabetes in early adulthood (16 to 38 years) among men and...
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Maternal gestational diabetes and childhood adiposity risk from 6 to 8 years of age
Background/objectivePrevious studies found conflicting results on the association between maternal gestational diabetes mellitus (GDM) and childhood...
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Childhood adiposity and novel subtypes of adult-onset diabetes: a Mendelian randomisation and genome-wide genetic correlation study
Aims/hypothesisWe investigated whether the impacts of childhood adiposity on adult-onset diabetes differ across proposed diabetes subtypes using a...
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Low birthweight and overweight during childhood and young adulthood and the risk of type 2 diabetes in men: a population-based cohort study
Aims/hypothesisThis study aimed to determine the relative contributions of low birthweight and overweight during childhood and young adulthood to the...
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Clinical and biochemical profile of childhood–adolescent-onset type 1 diabetes and adult-onset type 1 diabetes among Asian Indians
AimTo compare the clinical and biochemical profile and prevalence of complications among childhood/adolescent-onset (CAO; onset of diabetes< 20 years...
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Influence of preterm birth on the association between gestational diabetes mellitus and childhood developmental vulnerability: a causal mediation analysis
BackgroundEpidemiological studies examining the direct and indirect effects of gestational diabetes mellitus (GDM) on offspring early childhood...
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Gestational age at birth and type 1 diabetes in childhood and young adulthood: a nationwide register study in Finland, Norway and Sweden
Aims/hypothesisChildren and adults born preterm have an increased risk of type 1 diabetes. However, there is limited information on risk patterns...
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Inadequate care and excessive overprotection during childhood are associated with the presence of diabetes mellitus in adulthood in a general Japanese population: a cross-sectional analysis from the Hisayama Study
ObjectiveTo investigate associations between parenting styles during childhood and diabetes in adulthood in a Japanese community.
Methods ...
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Genetic evidence that high BMI in childhood has a protective effect on intermediate diabetes traits, including measures of insulin sensitivity and secretion, after accounting for BMI in adulthood
Aims/hypothesisDetermining how high BMI at different time points influences the risk of develo** type 2 diabetes and affects insulin secretion and...
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The incidence of childhood-onset type 1 diabetes, time trends and association with the population composition in Sweden: a 40 year follow-up
Aims/hypothesisDuring the 1980s and 1990s, the incidence of childhood-onset type 1 diabetes more than doubled in Sweden, followed by a plateau. In...
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Early-childhood body mass index and its association with the COVID-19 pandemic, containment measures and islet autoimmunity in children with increased risk for type 1 diabetes
Aims/hypothesisThe aim of this study was to determine whether BMI in early childhood was affected by the COVID-19 pandemic and containment measures,...
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Childhood diabetes mellitus and early-onset kidney diseases later in life: a nationwide population-based matched cohort study
BackgroundThe empirical evidence remains inconclusive for an association between diabetes mellitus (DM) in children and early-onset kidney disease...
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Early-life determinants of childhood plasma insulin levels: implications for primordial prevention of diabetes
BackgroundWe earlier reported prematurity as an independent risk factor for elevated insulin levels. Investigation is still lacking on the influence...
