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The value of the defence postmortem examination in England and Wales
The defence or second postmortem examination is instructed by the defence legal team, per defendant, following an initial postmortem examination...
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Implementing Germ Defence digital behaviour change intervention via all primary care practices in England to reduce respiratory infections during the COVID-19 pandemic: an efficient cluster randomised controlled trial using the OpenSAFELY platform
BackgroundGerm Defence ( www.germdefence.org ) is an evidence-based interactive website that promotes behaviour change for infection control within...
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Military Perspectives on the Provision of Spiritual Care in the Australian Defence Force: A Cross-Sectional Study
A module to explore perspectives on chaplaincy services was included in an online enterprise survey randomly distributed to members of the Australian...
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Physical and technical demands of offence, defence, and contested phases of play in Australian Football
BackgroundThis study compared the physical demands and effect of field location for different phases of play (offence, defence and contested), and...
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A bioavailable form of curcumin suppresses cationic host defence peptides cathelicidin and calprotectin in a murine model of collagen-induced arthritis
Curcumin, a component of the South-Asian spice turmeric, elicits anti-inflammatory functions. We have previously demonstrated that a highly...
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FXR-FGF19 signaling in the gut–liver axis is dysregulated in patients with cirrhosis and correlates with impaired intestinal defence
Background and aimsExperimental studies linked dysfunctional Farnesoid X receptor (FXR)-fibroblast growth factor 19 (FGF19) signaling to liver...
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A new perspective on positive symptoms: expression of damage or self-defence mechanism of the brain?
Usually, positive neurological symptoms are considered as the consequence of a mere, afinalistic and abnormal increase in function of specific brain...
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FABP4-mediated lipid droplet formation in Streptococcus uberis-infected macrophages supports host defence
Foamy macrophages containing prominent cytoplasmic lipid droplets (LDs) are found in a variety of infectious diseases. However, their role in Streptoco...
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GSDMD contributes to host defence against Staphylococcus aureus skin infection by suppressing the Cxcl1–Cxcr2 axis
Gasdermin D (GSDMD), a member of the gasdermin protein family, is a caspase substrate, and its cleavage is required for pyroptosis and IL-1β...
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Primary Care implementation of Germ Defence, a digital behaviour change intervention to improve household infection control during the COVID-19 pandemic: A structured summary of a study protocol for a randomised controlled trial
ObjectivesTo examine the effectiveness of randomising dissemination of the Germ Defence behaviour change website via GP practices across England UK.
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An Ethical Examination of Donor Anonymity and a Defence of a Legal Ban on Anonymous Donation and the Establishment of a Central Register
Many if not most sperm donors in the early years of IVF donated under conditions of anonymity. There is, however, a growing awareness of the ethical...
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How to boost the immune defence prior to respiratory virus infections with the special focus on coronavirus infections
The emergence of the novel coronavirus SARS-CoV-2, which causes severe respiratory tract infections in humans (COVID-19), has become a global health...
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Host defence peptide LEAP2 contributes to antimicrobial activity in a mustache toad (Leptobrachium liui)
BackgroundThe liver-expressed antimicrobial peptide 2 (LEAP2) is essential in host immunity against harmful pathogens and is only known to act as an...
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Studies of Defence Mechanisms and Inflammatory Reactions in the Bovine Teat using a New Experimental Method
Bovine intramammary infections are usually caused by microorganisms entering through the teat canal. The teat canal normally acts as a mechanical and...
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Rhamnus alaternus aqueous extract enhances the capacity of system redox defence and protects hepatocytes against aluminum chloride toxicity in rats
BackgroundThis study was designed to evaluate the protective effects of a Rhamnus alaternus aqueous extract (RAAE) on aluminum chloride-induced...
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Rapid screening of riot control agents using DART-TD-HRMS
PurposeRiot Control Agents (RCAs) are chemicals used in law enforcement for non-lethal riot control and use in conflicts between states that violates...
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Transcriptome analysis of PK-15 cells expressing CSFV NS4A
BackgroundClassical swine fever (CSF) is a severe disease of pigs that results in huge economic losses worldwide and is caused by classical swine...
