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Interactions between overweight/obesity and alcohol dependence impact human brain white matter microstructure: evidence from DTI
There is inconsistent evidence for an association of obesity with white matter microstructural alterations. Such inconsistent findings may be related...
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Prevalence of substance use disorders and associations with mindfulness, impulsive personality traits and psychopathological symptoms in a representative sample of adolescents in Germany
Adolescence is a critical phase for the development of substance use disorders (SUDs). For Europe and Germany, there are limited data on problematic...
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Changes of neurofilament light chain in patients with alcohol dependence following withdrawal and the genetic effect from ALDH2 Polymorphism
Neurofilament light chain (NFL), as a measure of neuroaxonal injury, has recently gained attention in alcohol dependence (AD). Aldehyde dehydrogenase...
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Effect of a Care Management Intervention on 12-Month Drinking Outcomes Among Patients With and Without DSM-IV Alcohol Dependence at Baseline
BackgroundThe CHOICE care management intervention did not improve drinking relative to usual care (UC) for patients with frequent heavy drinking at...
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Data-driven study on resting-state functional magnetic resonance imaging during early abstinence of alcohol dependence in male patients and its predictive value for relapse
BackgroundAlcohol dependence is a mental disorder with a high relapse rate. However, specific neuroimaging biomarkers have not been determined for...
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Somatic symptoms mediate the association between subclinical anxiety and depressive symptoms and its neuroimaging mechanisms
BackgroundSubclinical anxiety, depressive and somatic symptoms appear closely related. However, it remains unclear whether somatic symptoms mediate...
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Genomic risk for post-traumatic stress disorder in families densely affected with alcohol use disorders
Recent genome-wide association studies (GWAS) have identified genetic markers of post-traumatic stress disorder (PTSD) in civilian and military...
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Attention-deficit/hyperactivity disorder symptoms and subsequent cardiometabolic disorders in adults: investigating underlying mechanisms using a longitudinal twin study
BackgroundEmerging research suggests that attention-deficit/hyperactivity disorder (ADHD) increases the risk for cardiovascular (CVDs) and metabolic...
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Network Analysis of the Structure of the Core Symptoms and Clinical Correlates in Comorbid Schizophrenia and Gambling Disorder
Few studies have analyzed the clinical profile of treatment-seeking patients with the comorbid presence of schizophrenia (SCZ) and gambling disorder...
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Functional and clinical outcomes of FMRI-based neurofeedback training in patients with alcohol dependence: a pilot study
Identifying treatment options for patients with alcohol dependence is challenging. This study investigates the application of real-time functional...
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Can a History of Childhood Trauma Impact the Effectiveness of Treatment in Individuals with Alcohol Use Disorders? A 2.5- and 5-Year Follow-up
Experienced childhood trauma (CT) is prevalent in individuals with alcohol use disorders (AUDs). Few studies examine how experienced CT affects...
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Prodromal symptoms and the duration of untreated psychosis in first episode of psychosis patients: what differences are there between early vs. adult onset and between schizophrenia vs. bipolar disorder?
To assess the role of age (early onset psychosis-EOP < 18 years vs. adult onset psychosis-AOP) and diagnosis (schizophrenia spectrum disorders-SSD...
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Exploring Racial/Ethnic Disparities in Substance Dependence and Serious Psychological Distress among US Veterans
ObjectivesThere are substantial racial/ethnic disparities in substance use and mental health among civilian populations, but few studies have...
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Relationship between plasma TNF-α levels and agitation symptoms in first episode patients with schizophrenia
BackgroundIncreasing evidence suggested that immune abnormalities involved in the pathophysiology of schizophrenia. However, the relationship between...
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Efficacy, safety, and tolerability of serotonin-norepinephrine reuptake inhibitors in controlling ADHD symptoms: a systematic review and meta-analysis
IntroductionThe aim of this study is to assess the effectiveness of serotonin-norepinephrine reuptake inhibitors (SNRIs) in managing ADHD symptoms...
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Cannabis use and dependence among festival attendees: results from the French OCTOPUS survey
BackgroundChronic use of cannabis is associated with an increased risk of psychosocial, mental and physical health impairments. Sociohealth...
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Are there links between Alzheimer’s disease and ADHD? The efficacy of acetylcholinesterase inhibitors and NMDA receptor antagonists in controlling ADHD symptoms: a systematic review
BackgroundTo assess the effectiveness, safety, and tolerability of anti-Alzheimer agents (memantine, galantamine, rivastigmine, and donepezil) in...
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Are Comorbid Disorders Associated with Changes in Gambling Activity? A Longitudinal Study of Younger and Older Subjects with DSM-IV Pathological Gambling
This study investigates the association of comorbid disorders with gambling activity in a longitudinal follow-up study of younger and older adult...
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Characterizing Marijuana Use Disorders (DSM-5) — National Survey on Drug Use and Health, United States, 2020
In 2019, Marijuana Use Disorder (MUD) (DSM-IV) affected approximately 4.8 million (1.8%) Americans aged 12 and older. Given the continued evolving...
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Negative bias in early and late cognitive processing of coronary heart disease patients with depressive symptoms: an EPR study
BackgroundThe purpose of this research was to explore the underlying mechanisms of cognitive impairments in patients with coronary heart disease...
