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Genotoxic effect of Tamiflu and Adamine on DNA content in male albino mice
BackgroundTamiflu (Oseltamivir) and Adamine (Amantadine HCl) are antiviral drugs which are used for prevention and treatment for influenza. The...
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Flow-cytometry Assessment of DNA content and Immunophenoty** of Immune-cells in Lymph-node-specimens as a Potential Diagnostic Signature of Aggressiveness in B-Non-Hodgkin Lymphomas
Flow-cytometry (FC) is a powerful tool that can assist in lymphoma diagnosis in lymph node (LN) specimens. Although lymphoma diagnosis and...
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Mature oocyte dysmorphisms may be associated with progesterone levels, mitochondrial DNA content, and vitality in luteal granulosa cells
PurposeTo identify whether follicular environment parameters are associated with mature oocyte quality, embryological and clinical outcomes.
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Mitochondrial DNA content: a new potential biomarker for Sudden Infant Death Syndrome
BackgroundSudden Infant Death Syndrome (SIDS) occurs in apparently healthy infants and is unpredictable and unexplained despite thorough...
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Analysis of cellular and cell free mitochondrial DNA content and reactive oxygen species levels in maternal blood during normal pregnancy: a pilot study
BackgroundAlterations in mitochondrial signatures such as mitochondrial DNA (mtDNA) content in maternal blood have been linked to pregnancy-related...
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Diagnostic models to predict nuclear DNA and mitochondrial DNA recovery from incinerated teeth
Teeth are frequently used for human identification from burnt remains, as the structure of a tooth is resilient against heat exposure. The intricate...
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Persistent or recurrent Barrett’s neoplasia after an endoscopic therapy session is associated with DNA content abnormality and can be detected by DNA flow cytometric analysis of paraffin-embedded tissue
Endoscopic therapy is currently the standard of care for the treatment of high-grade dysplasia (HGD) or intramucosal adenocarcinoma (IMC) in patients...
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The effect of vitrification on blastocyst mitochondrial DNA dynamics and gene expression profiles
PurposeDoes vitrification/warming affect the mitochondrial DNA (mtDNA) content and the gene expression profile of blastocysts?
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Measure quantity of mitochondrial DNA in aged bones or calculate it from nuclear DNA quantitative PCR results?
Mitochondrial DNA (mtDNA) is of great value in forensics to procure information about a person when a next of kin, personal belongings, or other...
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Does blastocyst mitochondrial DNA content affect miscarriage rate in patients undergoing single euploid frozen embryo transfer?
PurposeTo determine whether the blastocyst mitochondrial DNA (mtDNA) content is related to the miscarriage rate in patients undergoing single euploid...
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An overview of DNA degradation and its implications in forensic caseworks
BackgroundDNA (deoxy-ribonucleic acid) is a fundamental molecule housing genetic information crucial for forensic casework. However, its integrity is...
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DNA methylation profiling identifies epigenetic signatures of early gastric cancer
Research on the DNA methylation status of gastric cancer (GC) has primarily focused on identifying invasive GC to develop biomarkers for diagnostic....
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Pathological consequences of DNA damage in the kidney
DNA lesions that evade repair can lead to mutations that drive the development of cancer, and cellular responses to DNA damage can trigger senescence...
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DNA Methylation in the Adaptive Response to Exercise
Emerging evidence published over the past decade has highlighted the role of DNA methylation in skeletal muscle function and health, including as an...
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Success rate of rapid DNA technology in kinship analysis for forensic purpose
Reducing the time required for DNA analysis in forensic genetics can yield significant benefits, both in determining genealogical relationships for...
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Impact of storage conditions and time on DNA yield from ammunition cartridges
Recovery of suitable amounts of DNA from ammunition cartridges for short tandem repeat (STR) or mitochondrial (mt) DNA analysis has been a challenge...
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Experimental congenital diaphragmatic hernia features an alteration of DNA sensing targets cGAS and STING
BackgroundThe pathogenesis of congenital diaphragmatic hernia (CDH) depends on multiple factors. Activation of the DNA-sensing...
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Brain water content in sudden unexpected infant death
The extensive and rapid development of the human brain during the first years of life complicates the postmortem diagnosis of brain edema in infancy....
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Presence of pathogen DNA in milk harvested from quarters is associated to changes in cows’ milk yield and composition
BackgroundIntramammary infection is the result of invasion and multiplication of microorganisms in the mammary gland and commonly leads to mastitis...
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Evaluation of face masks as a valuable forensic DNA evidence in the post-COVID era
After the onset of COVID-19 pandemic, a sharp surge in the usage of the face-masks throughout the globe has been observed. Pre-experiment survey of...