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Application of direct analysis in real-time mass spectrometry (DART-MS) in forensic science: a comprehensive review
BackgroundAs the rate of crime is constantly increasing, the workload on the forensic analyst also piles up. The availability of a limited number of...
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Kinematic 4D CT case-control study of wrist in dart throwing motion “in vivo”: comparison with other maneuvers
ObjectivesTo compare the diagnostic performance of scapholunate gap (SLG) measurements acquired with dart throwing (DT), radio-ulnar deviation (RUD),...
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The application of mass spectrometry imaging in traditional Chinese medicine: a review
Mass spectrometry imaging is a frontier technique which connects classical mass spectrometry with ion imaging. Various types of chemicals could be...
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An Update on the Clinical Evaluation of Antibody-Based Therapeutics in Acute Myeloid Leukemia
Purpose of ReviewThe advent of several targeted agents has revolutionized the treatment of acute myeloid leukemia (AML) in recent times; however,...
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An analysis of sex differences and socioeconomic deprivation among Canadian children with high blood pressure: a retrospective, cross-sectional study
BackgroundUnderstanding which children are at highest risk for high blood pressure (HBP) can inform surveillance and treatment. This study evaluated...
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Desmoid Tumors: A Comprehensive Review
Desmoid tumors (DT) are rare, locally aggressive, fibroblastic soft-tissue tumors that are characterized by infiltrative growth and can affect organs...
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M6A methylation modification in autoimmune diseases, a promising treatment strategy based on epigenetics
BackgroundN6-methyladenosine (m6A) methylation modification is involved in the regulation of various biological processes, including inflammation,...
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Comparing Substance Use Consequences between Serotonergic Psychedelics, MDMA, and other Drugs of Abuse Among United States Adults with History of Psychiatric Illness
Psychedelic-assisted therapy could transform treating psychiatric illness, but harms from exacerbating substance use disorder (SUD) among adults with...
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Targeted Alpha Therapy for Glioblastoma: Review on In Vitro, In Vivo and Clinical Trials
Glioblastoma (GB), a prevalent and highly malignant primary brain tumour with a very high mortality rate due to its resistance to conventional...
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Methyl (S)-2-(1–7 (5-fluoropentyl)-1H-indole-3-carboxamido)-3,3-dimethylbutanoate (5F-MDMB-PICA) intoxication in a child with identification of two new metabolites (ultra-high-performance liquid chromatography–tandem mass spectrometry)
PurposeMethyl (S)-2-(1–7 (5-fluoropentyl)-1H-indole-3-carboxamido)-3,3-dimethylbutanoate (5F-MDMA-PICA) intoxication in 1.5-year-old child was...
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Bone biopsies guided by augmented reality: a pilot study
PurposeTo test the technical feasibility of an augmented reality (AR) navigation system to guide bone biopsies.
MethodsWe enrolled patients...
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Multimodality Therapies for Localized Prostate Cancer
Purpose of ReviewMultimodality therapy including radical prostatectomy, radiation therapy, and hormone therapy are frequently deployed in the...
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Investigation of foot and mouth disease virus and other animal pathogens in cattle, buffaloes and goats at the interface with Akagera National Park 2017 – 2020
BackgroundFoot-and-Mouth Disease Virus (FMDV) is a positive-sense RNA virus of the family of the picornaviridæ that is responsible for one of the...
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Pulmonary large cell neuroendocrine carcinoma (LCNEC): a population-based study addressing recent molecular-genetic advances and emerging therapeutic approaches
BackgroundLarge cell neuroendocrine carcinoma (LCNEC) of the lung is a rare, aggressive cancer most commonly found in the lungs but not exclusively,...
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To metabolomics and beyond: a technological portfolio to investigate cancer metabolism
Tumour cells have exquisite flexibility in reprogramming their metabolism in order to support tumour initiation, progression, metastasis and...
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RNA methylation in vascular disease: a systematic review
Despite the rise in morbidity and mortality associated with vascular diseases, the underlying pathophysiological molecular mechanisms are still...
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Integrating Functional Imaging and Molecular Profiling for Optimal Treatment Selection in Neuroendocrine Neoplasms (NEN)
Purpose of ReviewGastroenteropancreatic NEN (GEP-NEN) are group of malignancies with significant clinical, anatomical and molecular heterogeneity....
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The potential of monoclonal antibodies for colorectal cancer therapy
Conventional chemotherapy has significant limitations for colorectal cancer (CRC) treatment, especially those who have developed metastatic...
