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Disordered eating in early childhood: DRD4 and DAT1 gene polymorphisms and quality of mother–child interaction
PurposeEating disturbances are complex heritable conditions that can be influenced by both genetic and environmental factors but are poorly studied...
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Genetic variants in dopamine pathways affect personality dimensions displayed by patients with eating disorders
PurposeWe aimed to analyze the association between common polymorphisms in dopamine pathways with personality dimensions frequently present in...
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Revisiting tandem repeats in psychiatric disorders from perspectives of genetics, physiology, and brain evolution
Genome-wide association studies (GWASs) have revealed substantial genetic components comprised of single nucleotide polymorphisms (SNPs) in the...
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Association study and a systematic meta-analysis of the VNTR polymorphism in the 3′-UTR of dopamine transporter gene and attention-deficit hyperactivity disorder
Attention-deficit hyperactivity disorder (ADHD) has been postulated to associate with dopaminergic dysfunction, including the dopamine transporter...
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Motivational learning biases are differentially modulated by genetic determinants of striatal and prefrontal dopamine function
Dopaminergic neurotransmission plays a pivotal role in appetitively motivated behavior in mammals, including humans. Notably, action and valence are...
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Genetics of Circadian and Sleep Measures in Adults: Implications for Sleep Medicine
Purpose of ReviewIn this review, we comprehensively discuss recent reports of heritability and genetic associations using candidate gene and...
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Molecular genetics of cocaine use disorders in humans
Drug addiction, one of the major health problems worldwide, is characterized by the loss of control in drug intake, craving, and withdrawal. At the...
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Dopaminergic Genetic Variation Influences Aripiprazole Effects on Alcohol Self-Administration and the Neural Response to Alcohol Cues in a Randomized Trial
Dopamine (DA) signaling regulates many aspects of Alcohol Use Disorder (AUD). However, clinical studies of dopaminergic medications, including the DA...
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Personality as an intermediate phenotype for genetic dissection of alcohol use disorder
Genetic and environmental interactive influences on predisposition to develop alcohol use disorder (AUD) account for the high heterogeneity among AUD...
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The dopamine-related polymorphisms BDNF, COMT, DRD2, DRD3, and DRD4 are not linked with changes in CSF dopamine levels and frequency of HIV infection
We showed previously that higher levels in CSF dopamine in HIV patients are associated with the presence of the dopamine transporter (DAT)...
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Sleep Homeostasis, Metabolism, and Adenosine
Sleep is an integral and constitutive part of life, invariably observed in animals with even a simple nervous system. Importantly, sleep is an active...
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Interacting Effects of Naltrexone and OPRM1 and DAT1 Variation on the Neural Response to Alcohol Cues
Variation at a single nucleotide polymorphism in the μ -opioid receptor gene ( OPRM1 ), A118G (Asn40Asp), may moderate naltrexone (NTX) effects in...
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A review on experimental and clinical genetic associations studies on fear conditioning, extinction and cognitive-behavioral treatment
Fear conditioning and extinction represent basic forms of associative learning with considerable clinical relevance and have been implicated in the...
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Response to methylphenidate is not influenced by DAT1 polymorphisms in a sample of Brazilian adult patients with ADHD
Several lines of evidence suggest a relevant role for the dopamine transporter (DAT1) gene not only as a susceptibility factor for attention-deficit...