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Ferroptosis – a potential feature underlying neratinib-induced colonic epithelial injury
PurposeNeratinib, a small-molecule tyrosine kinase inhibitor (TKI) that irreversibly binds to human epidermal growth factor receptors 1, 2 and 4...
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Butyrate supplementation to pregnant mice elicits cytoprotection against colonic injury in the offspring
BackgroundMaternal diet during pregnancy can impact progeny health and disease by influencing the offspring’s gut microbiome and immune development....
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Colonic oxygen microbubbles augment systemic oxygenation and CO2 removal in a porcine smoke inhalation model of severe hypoxia
Inhalation injury can lead to pulmonary complications resulting in the development of respiratory distress and severe hypoxia. Respiratory distress...
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Colonic interposition in esophagectomy: an ACS-NSQIP study
IntroductionFor patients with cancer or injury of the esophagus, esophagectomy with reconstruction using the stomach (gastric pull-up, GPU) or colon...
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Colonic transposition using mid colon for corrosive oesophageal strictures
PurposeTo evaluate mid colon as a viable alternative for reconstruction in diffuse corrosive oesophageal stricture compared to other modes.
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Penetrating colon trauma – outcomes related to single versus multiple colonic injuries
IntroductionThere is no conclusive evidence to guide surgical management in the presence of multiple colonic injuries as opposed to a single colonic...
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Pneumo-mediastinum, pneumoperitoneum, and pneumo-scrotum with extensive increasing subcutaneous emphysema: a rare presentation of colonic perforation
BackgroundColonic perforation usually presents with classical signs of peritonitis. However, isolated retroperitoneal colonic perforation can present...
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Effect of huankuile on colon injury in rats with ulcerative colitis by reducing TNF-α and MMP9
ObjectiveTo explore the mechanism of huankuile (HKL) in colon injury repair in rats with ulcerative colitis (UC).
MethodsFifty SPF Wistar male rats...
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Ventricular bigeminy associated with myocardial ischemia in a dog with a colonic torsion: a case report
BackgroundVentricular bigeminy due to myocardial ischemia has been reported in humans as well as in canine patients with obstructive gastrointestinal...
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Colonic diverticular bleeding due to a rupture of an ileocolic artery pseudoaneurysm secondary to colonic diverticulitis
A 53-year-old woman with a history of recurrent right lower quadrant pain presented with slightly bloody stools in April 2023. She was initially...
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A challenging upper digestive tract continuity restoration after recurrent esophago-colonic anastomosis complications
BackgroundAcute and chronic complications in esophago-colonic anastomosis have a significant impact in the postoperative course of patients with...
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Acute colonic pseudo-obstruction: a retrospective review of the surgical outcomes
PurposeLimited data exist regarding the surgical outcomes of acute colonic pseudo-obstruction (ACPO), commonly referred to as Ogilvie syndrome, in...
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Cronkhite‒Canada syndrome as inflammatory hamartomatous polyposis: new evidence from whole transcriptome sequencing of colonic polyps
BackgroundCronkhite-Canada syndrome (CCS) is a rare, nonhereditary disease characterized by diffuse gastrointestinal polyposis and ectodermal...
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Effective, safe and efficient porcine model of Forrest Ib bleeding gastric and colonic ulcers
BackgroundDevelo** effective gastrointestinal (GI) bleeding animal models is necessary to advance endoscopic hemostasis methods and train...
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60-year-old male with rapidly progressive pneumocephalus caused by Clostridium septicum in the setting of an occult colonic adenocarcinoma
BackgroundDisseminated Clostridium septicum infection is an uncommon complication associated with malignancies, particular colonic adenocarcinoma....
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Gliclazide Reduces Colitis-Associated Colorectal Cancer Formation by Deceasing Colonic Inflammation and Regulating AMPK-NF-κB Signaling Pathway
BackgroundGliclazide is a potential anti-cancer drug candidate for preventing carcinogenesis. However, the effect of gliclazide on colitis-associated...
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Microvascular reconstruction in salvaging the gastric conduit post-esophagectomy after iatrogenic right gastroepiploic vessel injury
The preservation of the right gastroepiploic vessels is essential to ensure proper perfusion of the gastric conduit following esophagectomy. The loss...
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Endoscopic management of low output recurrent colonic fistula or leak after anterior resection for rectal cancer: a randomized controlled trial
BackgroundColonic anastomotic leak and fistula following anterior resection surgery for rectal cancer are associated with high mortality rates. The...
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Applications of indocyanine greenenhanced fluorescence in the laparoscopic treatment of colonic stricture after necrotizing enterocolitis
BackgroundThe status of anastomotic blood perfusion is associated with the occurrence of anastomotic leakage after intestinal anastomosis....
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The Gut Microbiome and Colonic Motility Disorders: A Practical Framework for the Gastroenterologist
Purpose of ReviewColonic motility disorders may be influenced by the gut microbiota, which plays a role in modulating sensory and motor function....
