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Detection of Endometriosis Lesions Using Gd-Based Collagen I Targeting Probe in Murine Models of Endometriosis
PurposeEndometriosis is a chronic condition characterized by high fibrotic content and affecting about 10% of women during their reproductive years....
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Type IV Collagen Promotes Adipogenic Differentiation of Adipose Stem Cells
Type IV collagen is a major component of the extracellular matrix in adipose tissue. It is secreted during the lipogenic differentiation of...
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Characterization of biochemical and optical properties of Nile tilapia (Oreochromis niloticus) corneal collagen
BackgroundCollagen extracted from fish body parts is a promising biological material. It has an important role in many pharmaceutical, medical...
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Role of human adipose-derived stem cells (hADSC) on TGF-β1, type I collagen, and fibrosis degree in bladder obstruction model of Wistar rats
IntroductionBladder outlet obstruction (BOO) was caused by a series of histological and biochemical changes in the bladder wall, through the...
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Tissue inhibitor of matrix metalloprotinase-1 and collagen type IV in HCV-associated cirrhosis and grading of esophageal varices
BackgroundEsophageal varices are abnormally dilated submucosal veins of the esophagus which develop as a result of portal hypertension due to...
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Turnover of type I and III collagen predicts progression of idiopathic pulmonary fibrosis
BackgroundIdiopathic pulmonary fibrosis (IPF) is characterized by the accumulation of fibrillar collagens in the alveolar space resulting in reduced...
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A serological biomarker of type I collagen degradation is related to a more severe, high neutrophilic, obese asthma subtype
BackgroundAsthma is a heterogeneous disease; therefore, biomarkers that can assist in the identification of subtypes and direct therapy are highly...
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The collagen matrix regulates the survival and function of pancreatic islets
The extracellular matrix (ECM) provides an appropriate microenvironment for many kinds of cells, including pancreatic cells. Collagens are the most...
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Influence of type I collagen polymorphisms and risk of anterior cruciate ligament rupture in athletes: a case-control study
BackgroundAnterior cruciate ligament (ACL) rupture is a common and severe knee injury in sports and occurs mostly due to noncontact injuries. There...
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Changes in type VI collagen degradation reflect clinical response to treatment in rheumatoid arthritis patients treated with tocilizumab
ObjectivesRheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammation in multiple articular joints, causing pain, joint...
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Collagen turnover is associated with cardiovascular autonomic and peripheral neuropathy in type 1 diabetes: novel pathophysiological mechanism?
BackgroundDiabetic cardiovascular autonomic neuropathy (CAN) and distal symmetrical polyneuropathy (DSPN) are severe diabetic complications. Collagen...
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Duraplasty using a combination of a pedicled dural flap and collagen matrix in posterior fossa decompression for pediatric Chiari malformation type 1 with syrinx
PurposeIn posterior fossa decompression for pediatric Chiari malformation type 1 (CM-1), duraplasty methods using various dural substitutes have been...
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Efficacy and Safety of Type III Collagen Lyophilized Fibers Using Mid-to-Deep Dermal Facial Injections for the Correction of Dynamic Facial Wrinkles
BackgroundThis study aimed to evaluate the therapeutic efficacy and safety of injecting Type III collagen lyophilized fibers into the mid-to-deep...
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Single-cell RNA sequencing of submandibular gland reveals collagen type XV-positive fibroblasts as a disease-characterizing cell population of IgG4-related disease
ObjectivesIgG4-related disease (IgG4-RD) is a systemic autoimmune disease with an unknown etiology, affecting single/multiple organ(s). Pathological...
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Recombinant Platelet-Derived Growth Factor-BB (rhPDGF-BB) Augmented Collagen Grafting for Oral Mucosal Defect Reconstruction
ObjectiveTo assess the suitability of collagen grafting and compare the outcomes between rhPDGF-BB (recombinant human platelet-derived growth...
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Circulating levels of endotrophin and cross-linked type III collagen reflect liver fibrosis in people with HIV
Background and aimsLiver-associated complications still frequently lead to mortality in people with HIV (PWH), even though combined antiretroviral...
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Trimerization profile of type IV collagen COL4A5 exon deletion in X-linked Alport syndrome
BackgroundAlport syndrome (AS) is a genetic kidney disease caused by a mutation in type IV collagen α3, α4, and α5, which are normally secreted as...
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Aging impairs the osteocytic regulation of collagen integrity and bone quality
Poor bone quality is a major factor in skeletal fragility in elderly individuals. The molecular mechanisms that establish and maintain bone quality,...
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Visualizing Collagen Fibrils in the Cochlea’s Tectorial and Basilar Membranes Using a Fluorescently Labeled Collagen-Binding Protein Fragment
PurposeA probe that binds to unfixed collagen fibrils was used to image the shapes and fibrous properties of the TM and BM. The probe (CNA35) is...
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Collagen patch cover facilitates recovery of bowel function after laparoscopic colectomy
BackgroundNumerous factors can influence bowel movement recovery and anastomotic healing in colorectal surgery, and poor healing can lead to severe...
