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Cardiac electrical abnormalities in childhood acute lymphoblastic leukemia survivors: a systematic review
PurposeThe aim was to provide evidence about the prevalence, incidence, and risk factors of cardiac electrical abnormalities in childhood acute...
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Relapsed Acute Lymphoblastic Leukemia
Outcomes for children with acute lymphoblastic leukemia (ALL) have improved worldwide to >85%. For those who relapse, outcomes have remained static...
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The Prevalence, Risk Factors and Cardiometabolic Complications of Obesity in Childhood Survivors of Acute Lymphoblastic Leukemia
Prevalence, risk factors and metabolic complications of overweight/obesity (OW/OB) are not well described in the childhood survivors of acute...
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Prognostic implications of CD9 in childhood acute lymphoblastic leukemia: insights from a nationwide multicenter study in China
The outcomes of children with acute lymphoblastic leukemia (ALL) have been incrementally improved with risk-directed chemotherapy but therapy...
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t(1;4) translocation in a child with acute lymphoblastic leukemia: a case report
BackgroundAcute lymphoblastic leukemia is the most common childhood cancer, with an 80% frequency in children between 1 and 10 years old. The outcome...
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TBI, etoposide, and cyclophosphamide conditioning for intermediate-risk relapsed childhood acute lymphoblastic leukemia
BackgroundIn children with intermediate-risk relapsed acute lymphoblastic leukemia (ALL), allogeneic hematopoietic stem cell transplantation...
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Central nervous system involvement in childhood acute lymphoblastic leukemia: challenges and solutions
Delivery of effective anti-leukemic agents to the central nervous system (CNS) is considered essential for cure of childhood acute lymphoblastic...
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Progression of brain injuries associated with methotrexate chemotherapy in childhood acute lymphoblastic leukemia
BackgroundBrain bases and progression of methotrexate-associated neurotoxicity and cognitive disturbances remain unknown. We tested whether brain...
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KIF11 serves as a cell cycle mediator in childhood acute lymphoblastic leukemia
ObjectiveTo identify key gene in childhood acute lymphoblastic leukemia (ALL) through weighted gene co-expression network analysis (WGCNA), and their...
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Long-term neurotoxicity among childhood acute lymphoblastic leukaemia survivors enrolled between 1971 and 1998 in EORTC Children Leukemia Group studies
Survival after childhood acute lymphoblastic leukemia (ALL) has increased over the last 40 years with an overall survival above 90%. Survivors may...
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Prevalence and risk factors of disseminated intravascular coagulation in childhood acute lymphoblastic leukemia
BackgroundFew studies have examined disseminated intravascular coagulation (DIC) in childhood acute lymphoblastic leukemia (ALL). Our aims were to...
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Movement efficiency in survivors of childhood acute lymphoblastic leukemia: a report from the St. Jude lifetime cohort study
PurposeMovement efficiency, a measure of neuromuscular biomechanics, may be modified by physical activity. We aimed to assess the risk of and risk...
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Relationship between cardiac mechanical properties and cardiac magnetic resonance imaging at rest in childhood acute lymphoblastic leukemia survivors
The characterization of cardiac mechanical properties may contribute to better understanding of doxorubicin-induced cardiotoxicity. Our study aims to...
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The association of environmental factors with neurocognitive outcomes in survivors of childhood acute lymphoblastic leukemia (ALL)
PurposeTo investigate the association of environmental factors, rehabilitation services during therapy and socioeconomic status (SES – insurance...
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Prognostic factors impacting post-transplant outcomes in adult T-cell acute lymphoblastic leukemia: a registry-based study by the EBMT acute leukemia working party
T-cell acute lymphoblastic leukemia (T-ALL) predominantly affects individuals in late childhood and young adulthood. Allogeneic hematopoietic stem...
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Diagnostic significance of cerebrospinal fluid flow cytometry in Chinese children with B lineage acute lymphoblastic leukemia
BackgroundCentral nervous system leukemia (CNSL) is one of the major causes of the poor prognosis of childhood leukemia. We aimed to compare the...
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Identification of a novel MEF2C::SS18L1 fusion in childhood acute B-lymphoblastic leukemia
PurposeLeukemia-associated fusion genes are closely related to the occurrence, development, diagnosis, and treatment of leukemia. DNA microarrays and...
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Measurable residual disease study through three different methods can anticipate relapse and guide early interventions in childhood acute lymphoblastic leukemia
IntroductionAcute lymphoblastic leukemia (ALL) is the most common cancer among children. Measurable residual disease (MRD, previously named minimal...
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Acute Lymphoblastic Leukemia with Central Nervous System Involvement—Challenges in Management
The survival of patients with acute lymphoblastic leukemia (ALL) has dramatically improved during the last six decades. This improvement is secondary...
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St. Jude Total Therapy studies from I to XVII for childhood acute lymphoblastic leukemia: a brief review
The therapy design of childhood acute lymphoblastic leukemia (ALL) has evolved over the past 60 years. The St. Jude Children’s Research Hospital has...