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Significance of chemotherapy-free interval and tumor regression grade in patients with recurrent esophageal squamous cell carcinoma receiving chemotherapy with fluorouracil and platinum after esophagectomy following preoperative chemotherapy
BackgroundIn Japan, standard treatment for locally advanced esophageal squamous cell carcinoma (ESCC) includes preoperative chemotherapy with...
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Cholangitis and Interruptions of Neoadjuvant Chemotherapy Associate with Reduced Overall and Progression-Free Survival in Pancreatic Cancer
BackgroundInterrupting chemotherapy may explain the reduced overall survival (OS) in patients with pancreatic cancer (PC) with cholangitis....
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A prognostic model for predicting progression-free survival in patients with advanced non-small cell lung cancer after image-guided microwave ablation plus chemotherapy
ObjectivesThis study aimed to build and validate a prediction model that can predict progression-free survival (PFS) in patients with advanced...
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Evaluation of Circulating Cell-Free DNA Levels in Predicting Operability During Interval Cytoreduction for Advanced Epithelial Ovarian Cancers
BackgroundThis study aims to evaluate the role of circulating cell-free DNA (cfDNA) levels in predicting optimal cytoreduction (OCR) during interval...
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Strain ultrasonic elastography imaging features of locally advanced breast cancer: association with response to neoadjuvant chemotherapy and recurrence-free survival
BackgroundDue to the highly heterogeneity of the breast cancer, it would be desirable to obtain a non-invasive method to early predict the treatment...
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Neoadjuvant anthracycline-based (5-FEC) or anthracycline-free (docetaxel/carboplatin) chemotherapy plus trastuzumab and pertuzmab in HER2 + BC patients according to their TOP2A: a multicentre, open-label, non-randomized phase II trial
PurposePrevious studies have reported the benefit of dual HER2-targeting combined to neoadjuvant chemotherapy in HER2-amplified breast cancer...
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Neoadjuvant chemotherapy followed by interval debulking surgery for advanced epithelial ovarian cancer: GOTIC-019 study
IntroductionThree randomized controlled trials have resulted in extremely extensive application of the strategy of using neoadjuvant chemotherapy...
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Does the time interval from neoadjuvant camrelizumab combined with chemotherapy to surgery affect outcomes for locally advanced esophageal squamous cell carcinoma?
BackgroundThere is currently no consensus on the optimal interval time between neoadjuvant therapy and surgery, and whether prolonged time interval...
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Multi-center evaluation of machine learning-based radiomic model in predicting disease free survival and adjuvant chemotherapy benefit in stage II colorectal cancer patients
BackgroundOur study aimed to explore the potential of radiomics features derived from CT images in predicting the prognosis and response to adjuvant...
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Contrast-free MRI quantitative parameters for early prediction of pathological response to neoadjuvant chemotherapy in breast cancer
ObjectivesTo assess early changes in synthetic relaxometry after neoadjuvant chemotherapy (NAC) for breast cancer and establish a model with...
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CT-based radiomics signature analysis for evaluation of response to induction chemotherapy and progression-free survival in locally advanced hypopharyngeal carcinoma
ObjectivesTo establish and validate a CT radiomics model for prediction of induction chemotherapy (IC) response and progression-free survival (PFS)...
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Laparoscopic versus open approach for interval cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) in advanced epithelial ovarian cancer: a matched comparative study
BackgroundThe use of the laparoscopic approach for the treatment of carcinomatosis from epithelial ovarian cancer (EOC) is controversial. The aim of...
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Single Institute Experience with Neo-Adjuvant Chemotherapy and Interval Debulking Surgery in Advanced Endometrial Cancer
Our study aims to review the role of neoadjuvant chemotherapy (NACT) followed by interval debulking surgery (IDS) in patients with advanced...
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Outcomes of Laparoscopic Optimal Interval Cytoreduction Surgery (LOICS) in Patients with Advanced Ovarian Cancers Having Low Burden Disease
Laparoscopy has been increasingly utilised for cytoreduction surgery in patients with early ovarian cancers. The present study tries to assess the...
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18F-FDG PET/CT-based deep learning radiomics predicts 5-years disease-free survival after failure to achieve pathologic complete response to neoadjuvant chemotherapy in breast cancer
BackgroundThis study aimed to assess whether a combined model incorporating radiomic and depth features extracted from PET/CT can predict...
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Oncologic investigation of the interval from stent placement to surgery in patients with obstructive colorectal cancer
PurposeSelf-expandable metallic stent (SEMS) placement is widely used as a bridge to surgery (BTS) procedure for obstructive colorectal cancer....
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Assessing the Feasibility of Laparoscopic Interval Cytoreduction in Advanced Epithelial Ovarian Cancer
Laparoscopy has acquired an increasing role in the management of ovarian cancer. After the results of MISSION trial, laparoscopic cytoreduction could...
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Clinical application of radiotherapy in patients with oligometastatic ovarian cancer: a sharp tool to prolong the interval of systemic treatment
BackgroundWith the advances of radiation technology, treatment of oligometastatic disease, with limited metastatic burden, have more chances to...
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Progression-free survival on endocrine therapy, before or after chemotherapy, in hormone receptor-positive HER2-negative metastatic breast cancer
PurposeA major question when treating HR+/HER2− metastatic breast cancer (MBC) is whether early introduction of chemotherapy (CT) increases endocrine...
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Impact of the time interval between end of induction and autologous hematopoietic transplantation in newly diagnosed patients with multiple myeloma
Multiple Myeloma patients eligible for autologous hematopoietic transplantation (AHT) typically receive 3–6 cycles of induction therapy before...
