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Primary central nervous system lymphoma
Primary central nervous system lymphoma (PCNSL) is a rare type of non-Hodgkin lymphoma (NHL) manifesting in the brain, spinal cord, cerebrospinal...
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Role and application of chemokine CXCL13 in central nervous system lymphoma
Chemokine ligand 13 (CXCL13) and its chemokine receptor 5 (CXCR5) both play significant roles in the tumor microenvironment (TME). CXCL13 in...
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Imaging of central nervous system emergencies in oncology
Central nervous system (CNS) may be predisposed to devastating complications in cancer patients which may add to morbidity and mortality in this...
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The Role of Autophagy in Childhood Central Nervous System Tumors
Autophagy is a physiological process that occurs in normal tissues. Under external environmental pressure or internal environmental changes, cells...
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Treatment outcomes for response-based radiotherapy in children and adolescents with central nervous system germinoma: a prospective study
PurposeThe optimal dose and range of radiotherapy for central nervous system (CNS) germinoma have not yet been established. This study aimed to...
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Study on primary central nervous system lymphoma in pediatric patients
BackgroundPrimary central nervous system lymphoma (PCNSL) in pediatric patients presents diagnostic and treatment challenges, leading to delays and...
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Analysis of the genomic landscape of primary central nervous system lymphoma using whole-genome sequencing in Chinese patients
Primary central nervous system lymphoma (PCNSL) is an uncommon non-Hodgkin’s lymphoma with poor prognosis. This study aimed to depict the genetic...
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Outcomes of surgery and subsequent therapy for central nervous system oligoprogression in EGFR-mutated NSCLC patients
BackgroundOligoprogression is an emerging issue in patients with epidermal growth factor receptor (EGFR)-mutated non-small cell lung cancer (NSCLC)....
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Central nervous system tumours in neonates: what should the neonatologist know?
Central nervous system (CNS) tumours in neonates are relatively rare and present differently when compared with those occurring later in childhood in...
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Clinical factors, management, and outcomes of children under 3 years old with central nervous system tumors: single-center experience
PurposeChildren under 3 years old represent a notable portion, about 25 to 30%, of all central nervous system tumor (CNS) cases. Their clinical...
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Anticoagulant prescribing patterns in patients with primary central nervous system malignancies and secondary metastases
To evaluate the safety of direct oral anticoagulants (DOACs) versus low-molecular weight heparin (LMWH) in patients with central nervous system (CNS)...
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Recurrent central nervous system Rosai-Dorfman disease with KRAS mutation: a case report
BackgroundRosai-Dorfman disease (RDD) is a rare, non-Langerhans cell histiocytosis of unknown etiology. we report a very rare case of recurrent...
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Central nervous system embryonal tumors with EWSR1-PLAGL1 rearrangements reclassified as INI-1 deficient tumors at relapse
PurposeCentral nervous system (CNS) embryonal tumors are a diverse group of malignant tumors typically affecting pediatric patients that recently...
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Inflammatory myofibroblastic tumor of the lung involving the central nervous system in pediatric patients
IntroductionThe inflammatory myofibroblastic tumor (IMT) is a very rare lesion with an incidence of less than 0.1% of total neoplasms and with main...
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Spatial single cell analysis of tumor microenvironment remodeling pattern in primary central nervous system lymphoma
To determine the overall tumor microenvironment (TME), characteristics, and transition mechanisms in primary central nervous system lymphoma (PCNSL),...
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Pharmaceutical equivalent 5-aminolevulinic acid fluorescence guided resection of central nervous system tumors: feasibility, safeness and cost-benefit considerations
Purpose5-aminolevulinic acid (5-ALA) fluorescence-guided resection (FGR) has been an essential tool in the ‘standard of care’ of malignant gliomas....
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Primary intra-axial Ewing sarcoma of the central nervous system: report of a rare case with literature review
BackgroundPrimary intra-axial Ewing sarcoma (EWS) is extremely rare and a highly aggressive small blue round cell tumor in the central nervous system...
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Cauda equina syndrome in a patient with human immunodeficiency virus and secondary central nervous system lymphoma: a case report
BackgroundSecondary central nervous system lymphoma (SCNSL) is a known complication of immunocompromised patients with most cases involving the brain...
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Granulomatous Diseases of the Central Nervous System
Purpose of ReviewTo discuss the pathophysiology, key clinical features, necessary diagnostic evaluation, and current treatment regimens for...
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Recent advances in liquid biopsy of central nervous system lymphomas: case presentations and review of the literature
Surgical biopsy is the gold standard for diagnosing central nervous system (CNS) lymphomas. However, reliable liquid biopsy methods for diagnosing...