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Cardiac Amyloidosis Diagnosis and Treatment
Cardiac amyloidosis (CA) is caused by the accumulation of amyloid fibrils in the extracellular space of the myocardium, with clinical manifestations...
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Multi-parametric non-contrast cardiac magnetic resonance for the differentiation between cardiac amyloidosis and hypertrophic cardiomyopathy
AimTo evaluate the ability of fast strain-encoded (SENC) cardiac magnetic resonance (CMR) derived myocardial strain and native T1 map** to...
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Natriuretic Peptides and Cardiac Troponins: Markers of Disease Progression and Risk in Light Chain Cardiac Amyloidosis
Purpose of ReviewLight chain (AL) amyloidosis can cause an infiltrative cardiomyopathy that can result in symptomatic heart failure. The vague,...
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Outcomes of patients with cardiac amyloidosis undergoing percutaneous left atrial appendage occlusion
BackgroundThere is limited data on the safety and efficacy of left atrial appendage occlusion (LAAO) devices in patients with cardiac amyloidosis. We...
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Serum alpha 1 antitrypsin potent act as an early diagnostic biomarker for cardiac amyloidosis
Cardiac amyloidosis is a refractory cardiomyopathy with a poor prognosis and lacks effective treatments. N-terminal pro-brain natriuretic peptide...
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Detection and Diagnosis of Cardiac Amyloidosis in Egypt
Cardiac amyloidosis is a life-threatening disease that occurs when amyloid proteins, most commonly immunoglobulin light chain or transthyretin,...
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Advance of echocardiography in cardiac amyloidosis
Cardiac amyloidosis (CA) occurs when the insoluble fibrils formed by misfolded precursor proteins deposit in cardiac tissues. The early clinical...
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British Society of Echocardiography guideline for the transthoracic echocardiographic assessment of cardiac amyloidosis
These guidelines form an update of the BSE guideline protocol for the assessment of restrictive cardiomyopathy (Knight et al. in Echo Res Prac,...
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Challenges associated with managing treatment complications in an older patient with cardiac amyloidosis
BackgroundAmyloidosis, particularly wild-type transthyretin amyloidosis (ATTRwt), is an increasingly recognized cause of heart failure with preserved...
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A rare clinical case of systemic AA amyloidosis with cardiac involvement complicating ankylosing spondylitis: a case report
BackgroundAnkylosing spondylitis (AS) is a type of chronic inflammation that is most prevalent in young adults and is characterized by an...
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Extensive cardiac FDG uptake in a patient with AL amyloidosis
Cardiac AL amyloidosis is a medical emergency causing rapid deterioration of cardiac function; however, it remains to be a diagnostic challenge...
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Valvular heart disease in patients with cardiac amyloidosis
Cardiac amyloidosis (CA) is an underdiagnosed condition caused by the deposition of misfolded proteins, namely immunoglobulin light chains and...
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Imaging findings of right cardiac amyloidosis: impact on prognosis and clinical course
Cardiac involvement from amyloidosis is of growing interest in the overall literature. Despite cardiac amyloidosis (CA) has been considered for a...
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Current Therapies and Future Horizons in Cardiac Amyloidosis Treatment
Purpose of ReviewCardiac amyloidosis (CA) is a condition characterized by misfolding and extracellular deposition of proteins, leading to organ...
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Sex differences in transthyretin cardiac amyloidosis
Transthyretin cardiac amyloidosis (ATTR-CA) is a progressive disease characterized by the deposition of abnormal transthyretin protein fibrils in the...
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Light-chain cardiac amyloidosis for the non-expert: pearls and pitfalls
Cardiac amyloidosis (CA) is an uncommon, progressive, and fatal disease; the two main forms that can affect the heart are transthyretin CA and light...
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Clinical clues for suspecting wild-type transthyretin cardiac amyloidosis in patients with monoclonal gammopathy of undetermined significance: a case report
BackgroundMyeloproliferative disorders, including monoclonal gammopathy of undetermined significance (MGUS), are often associated with amyloid...
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Myocardial extracellular volume quantification in cardiac amyloidosis: a comparative study between cardiac computed tomography and magnetic resonance imaging
ObjectivesMyocardial extracellular volume (ECV) on computed tomography (CT), an alternative to cardiac magnetic resonance (CMR), has significant...
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Left ventricular assist device in cardiac amyloidosis: friend or foe?
The prevalence of cardiac amyloidosis has progressively increased over the last years, being recognized as a significant cause of heart failure. In...
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Changes in the diagnostic trajectory of transthyretin cardiac amyloidosis over six years
Awareness of transthyretin amyloid cardiomyopathy (ATTR-CM) has increased over the years due to diagnostic and therapeutic developments. Timely...