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Diagnostic Utility of EWSR1 in Clear Cell Odontogenic Carcinoma: A Systematic Review
In the 2022, World Health Organisation classification of odontogenic tumours, the clear cell odontogenic carcinoma is designated as a malignant...
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Assessment of glypican-3 immune expression in ameloblastoma, ameloblastic fibroma, ameloblastic carcinoma (pilot study)
BackgroundOdontogenic tumors a variety of benign and malignant lesions developed exclusively in the jaws. They are known to have variable clinical...
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Squamous Cell Carcinoma Arising from Perianal Buschke-Lowenstein Tumor (Giant Condyloma Acuminatum): Comprehensive Literature Review
PurposeThis study aims to provide an overview of the literature on carcinoma arising from giant perianal condyloma acuminatum.
Methods ... -
Proliferative epithelial changes in tumour adjacent tissue in Sri Lankan women with breast carcinoma: do morphological changes support molecular models of breast carcinogenesis?
BackgroundThe multistep molecular model of breast carcinogenesis is based on the oestrogen receptor(ER) status of the tumour. Its two main arms...
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Diagnostic Utility of Expression Pattern of S100/Mammaglobin/SOX10/DOG 1 Immunohistochemistry in Differentiation of Secretory and Acinic Cell Carcinoma: A Systematic Review and Meta-Analysis
Secretory carcinoma (SC) is a relatively new disease entity, separate from acinic cell carcinoma (AciCC), which frequently displays ETV6-NTRK3 gene...
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Metaplastic carcinoma of the breast with squamous differentiation: prognostic factors and multidisciplinary treatment
BackgroundThe objective of this study was to analyze the characteristics of patients diagnosed with metaplastic carcinoma of the breast with squamous...
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Long-term outcomes of penile squamous cell carcinoma in men age ≤50 years old compared with men >50 years old from a single tertiary referral centre: a propensity score matched analysis
Penile cancer (PeCa) is rare, and the oncological outcomes in younger men are unclear. We aimed to analyse and compare oncological outcomes of men...
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Confocal endomicroscopy diagnostic criteria for early signet-ring cell carcinoma in hereditary diffuse gastric cancer
BackgroundRecognition of early signet-ring cell carcinoma (SRCC) in patients with hereditary diffuse gastric cancer (HDGC) undergoing endoscopic...
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A prospective phase II randomized study of docetaxel combined with lobaplatin versus TPF regimen induction chemotherapy followed by concurrent chemoradiotherapy for locally advanced head and neck squamous cell carcinoma
PurposeTo compare the toxicity and clinical efficacy of TL (docetaxel + lobaplatin) induction chemotherapy combined with lobaplatin concurrent...
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Metabolomics and integrated network pharmacology analysis reveal SNKAF decoction suppresses cell proliferation and induced cell apoptisis in hepatocellular carcinoma via PI3K/Akt/P53/FoxO signaling axis
BackgroundThere is no comprehensive treatment method for hepatocellular carcinoma (HCC); hence, research and development are still focused on...
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Clinical characteristics of breast cancer patients admitted to academic surgical wards in Tehran, Iran: an analytical cross-sectional study
BackgroundBreast cancer (BC) is the most commonly diagnosed cancer and the leading cause of cancer death among women. Knowledge of the clinical...
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Transoral Robotic surgery - excision of Tongue base Tumour with the Entire Hyoid bone in a Salvage Setting
Objectives – Transoral robotic surgery (TORS) is an already well established modality of treatment for early stage oropharyngeal cancer. This case...
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Impact of Revised Margin Negative Guidelines in Breast Cancer on Survival: Single Institution Audit
A positive resection margin after breast conserving surgery (BCS) is one of most significant risk factors for tumour recurrence. Guidelines have...
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A Multi-institutional Analysis of Factors Influencing the Rate of Positive MRI Biopsy Among Women with Early-Stage Breast Cancer
BackgroundThe use of preoperative magnetic resonance imaging (MRI) for early-stage breast cancer (ESBC) is increasing, but its utility in detecting...
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Vascular Control in Nose and Paranasal Sinus Tumours
Effective management of Tumors of Nose and Paranasal Sinuses (PNS) require adequate vascular control of the vessels supplying the tumor to facilitate...
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Adding merits of vacuum assisted biopsy in diagnosis and management of indeterminate breast micro-calcifications
BackgroundStereotactic guided biopsies have become the sampling method of choice in diagnosis of non-palpable breast microcalcifications which...
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Comparison of wire-guided localization (WGL) and radio-guided occult lesion localization (ROLL) in localization of non-palpable breast lesions
BackgroundThe number of patients with non-palpable breast lesions has increased gradually. This is because of the technological development in...
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Contrast enhanced digital mammography as a predictor of breast cancer in patient with pathological nipple discharge
BackgroundPathological nipple discharge (PND) commonly caused by benign diseases, but occasionally it signifies a major medical concern....
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A prediction model for skeletal muscle evaluation and computed tomography-defined sarcopenia diagnosis in a predominantly overweight cohort of patients with head and neck cancer
PurposeThis study investigates the feasibility of computed tomography (CT)-defined sarcopenia assessment using a prediction model for estimating the...