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Surgical intervention for non-small-cell lung cancer with minimal malignant pleural effusion
PurposeWe assessed the clinical significance of minimal malignant pleural effusion (MPE) using liquid-based cytology (LBC) and immunocytochemistry...
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Intraoperative rapid diagnosis of pleural lavage cytology in non-small cell lung cancer
ObjectivePositive pleural lavage cytology (PLC +) is a poor prognostic factor for non-small cell lung cancer (NSCLC). However, data on the impact of...
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Identification of a CEACAM5 targeted nanobody for positron emission tomography imaging and near-infrared fluorescence imaging of colorectal cancer
PurposeHere, we aim to identify a CEACAM5-targeted nanobody and demonstrate its application in positron emission tomography (PET) imaging and...
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Salivary gland pathologies: evolution in classification and association with unique genetic alterations
PurposeThe correct classification of salivary gland pathologies is crucial for choosing a treatment method and determining the prognosis. Better...
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Blood-derived lncRNAs as biomarkers for cancer diagnosis: the Good, the Bad and the Beauty
Cancer ranks as one of the deadliest diseases worldwide. The high mortality rate associated with cancer is partially due to the lack of reliable...
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Inhibition of Clusterin Represses Proliferation by Inducing Cellular Senescence in Pancreatic Cancer
BackgroundThe outcome of pancreatic ductal adenocarcinoma (PDAC) is unsatisfactory, and the identification of novel therapeutic targets is urgently...
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Feasibility and Safety of Laparoscopic D2 Gastrectomy in Combination with Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) in Patients with Gastric Cancer at High Risk of Recurrence—The PIPAC-OPC4 Study
BackgroundPatients with gastric adenocarcinoma (GAC) are at high risk of peritoneal recurrence despite perioperative chemotherapy and radical...
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Searching for the “Holy Grail” of breast cancer recurrence risk: a narrative review of the hunt for a better biomarker and the promise of circulating tumor DNA (ctDNA)
BackgroundThis paper is a narrative review of a major clinical challenge at the heart of breast cancer care: determining which patients are at risk...
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CD20/TNFR1 dual-targeting antibody enhances lysosome rupture-mediated cell death in B cell lymphoma
Obinutuzumab is a therapeutic antibody for B cell non-Hodgkin’s Lymphoma (BNHL), which is a glyco-engineered anti-CD20 antibody with enhanced...
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Exploration of biomarkers for the diagnosis, treatment and prognosis of cervical cancer: a review
As the fourth most diagnosed cancer, cervical cancer (CC) is one of the major causes of cancer-related mortality affecting females globally,...
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Investigating the role of circulating tumor cells in gastric cancer: a comprehensive systematic review and meta-analysis
Investigating the role of circulating tumor cells (CTCs) and their characteristics is still controversial in patients with gastric cancer (GC)....
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Keratin 17 is a sensitive and specific biomarker of urothelial neoplasia
There is a clinical need to identify novel biomarkers to improve diagnostic accuracy for the detection of urothelial tumors. The current study aimed...
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Detection of pagetoid urothelial intraepithelial neoplasia extending to the vagina by cervical screening cytology: a case report with renewed immunochemical summary
BackgroundPagetoid spread of urothelial carcinoma (UC) to the lower genital tract is quite a rare and diagnostically challenging condition. Pagetoid...
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Calcified mucinous adenocarcinoma of the stomach metastatic to the iris: a case report
BackgroundGastric cancer has a wide spectrum of clinical features, imaging manifestations, and pathology. Punctate calcifications in gastric cancer...
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Surgically resected pancreatic metastasis from nasal malignant melanoma: case report and literature review
A 13-mm mass was observed in the pancreatic head of a 70-year-old woman who had undergone melanoma resection in the nasal cavity 10 years earlier....
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What Is the Future of Circulating Tumor Cells in Colorectal Cancer?
Purpose of ReviewTo introduce recent progress on circulating tumor cell (CTC) research in colorectal cancer (CRC) and to highlight clinical...
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Vitamin D Supplementation is a Promising Therapy for Pancreatic Ductal Adenocarcinoma in Conjunction with Current Chemoradiation Therapy
BackgroundThe cancer-associated fibroblasts (CAFs) in pancreatic ductal adenocarcinoma (PDAC) are well known to play a dominant role in distant...
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Can urinary biomarkers replace cystoscopy?
PurposeDiagnosis and follow-up in patients with non-muscle invasive bladder cancer (NMIBC) rely on cystoscopy and urine cytology. The aim of this...
