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The effect of demographic, clinical, and pathological data on quality of life in rectum cancer
PurposeThe aims of the current study are to describe the quality of life among patients with rectal cancer and to determine the clinical and...
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Prognostic impact of tumor budding in rectal cancer after neoadjuvant therapy: a systematic review and meta-analysis
BackgroundTumor budding (TB) is a negative prognostic factor in colorectal cancer; however, its prognostic impact following neoadjuvant therapy for...
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The role of NLRP3 inflammasome in colorectal cancer: potential therapeutic target
All phases of carcinogenesis are affected by inflammation. Activation of the inflammasome is a crucial signaling mechanism that leads to acute and...
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Clinical practice guidelines for the nutrition of colorectal cancer patients: a systematic review
PurposeThe aim of this study is to rigorously assess the methodological quality of published clinical practice guidelines (CPGs) related to nutrition...
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Cannabis and cancer: unveiling the potential of a green ally in breast, colorectal, and prostate cancer
Cancer comes in second place on the list of causes of death worldwide. In 2018, the 5-year prevalence of breast cancer (BC), prostate cancer (PC),...
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Clinical features of young onset colorectal cancer patients from a large cohort at a single cancer center
PurposeThe aim of this study is to describe the demographics and clinical features of patients with young onset (YO) CRC.
MethodsA retrospective...
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Patients with Parkinson’s disease predict a lower incidence of colorectal cancer
BackgroundRecent theory on the “gut-brain axis” suggests a close relationship between the dysfunction of the gut and the disorders of the brain.
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Socioeconomic status on survival outcomes in patients with colorectal cancer: a cross-sectional study
BackgroundColorectal cancer (CRC) is widely acknowledged as a prevalent malignancy and the second most common cause of cancer-related mortality...
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The role of organoids in cancer research
Organoids are established through in vitro 3D culture, and they can mimic the structure and physiological functions of organs or tissues in vivo....
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Synthesis, preclinical evaluation and pilot clinical translation of [68Ga]Ga-PMD22, a novel nanobody PET probe targeting CLDN18.2 of gastrointestinal cancer
PurposeClaudin18.2 (CLDN18.2) is a novel target for diagnosis and therapy of gastrointestinal cancer. This study aimed to evaluate the safety and...
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Prognostic value of dynamic changes of pre- and post-operative tumor markers in colorectal cancer
BackgroundColorectal cancer (CRC) prognosis assessment is vital for personalized treatment plans. This study investigates the prognostic value of...
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Does particle radiation have superior radiobiological advantages for prostate cancer cells? A systematic review of in vitro studies
BackgroundCharged particle beams from protons to carbon ions provide many significant physical benefits in radiation therapy. However, preclinical...
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Risk prediction of second primary malignancies in patients after rectal cancer: analysis based on SEER Program
BackgroundThis study will focus on exploring the clinical characteristics of rectal cancer (RC) patients with Second Primary Malignancies (SPMs) and...
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Short-term efficacy analysis and comprehensive evaluation of laparoscopy for patients with rectal cancer-a prospective multi-center study
ObjectiveTo compare the short-term efficacy indicators of laparoscopic technique and open surgery in patients with rectal cancer surgery, and to...
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Efficient pathway for men fertility preservation in testicular cancer or lymphoma: a cross-sectional study of national 2018 data
BackgroundIn 15–49 years-old men, the main cancers are testicular cancer (TC) and lymphomas (L): freezing of ejaculated sperm is primarily used for...
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Comparison of short-term outcomes of laparoscopic surgery, robot-assisted laparoscopic surgery, and open surgery for lateral lymph-node dissection for rectal cancer: a network meta-analysis
This study attempted to compare short-term outcomes of laparoscopic surgery (LS), robot-assisted laparoscopic surgery (RS), and open surgery (OS) for...
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Preoperative contrast-enhanced CT imaging and clinicopathological characteristics analysis of mismatch repair-deficient colorectal cancer
BackgroundColorectal cancer (CRC) can develop through various pathogenetic pathways, and one of the primary pathways is high microsatellite...
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Resection of sigmoid cancer with bladder invasion using laparoscopic combined with a cystoscopic holmium laser: an innovative surgical procedure
The aim of this study was to introduce a new surgical procedure for the resection of sigmoid colon tumours invading the bladder by combining...
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The regulation of plasma gelsolin by DNA methylation in ovarian cancer chemo-resistance
BackgroundOvarian cancer (OVCA) is the most lethal gynecologic cancer and chemoresistance remains a major hurdle to successful therapy and survival...
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Integrated single-cell and bulk sequencing analyses with experimental validation identify the prognostic and immunological implications of CD226 in pan-cancer
PurposeCD226 (DNAM-1) is an activating receptor mainly expressed in CD8 + and NK cells. CD226 deficiency and blockade have been shown to impair tumor...
