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Critical illness-related corticosteroid insufficiency (CIRCI) in paediatric patients: a diagnostic and therapeutic challenge
Critical illness-related corticosteroid insufficiency or CIRCI is characterized by acute and life-threatening disfunction of...
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Critical illness-related corticosteroid insufficiency during difficult weaning from mechanical ventilation
BackgroundCritical illness-related corticosteroid insufficiency (CIRCI) is common during critical illness and is usually associated with poor...
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A schedule for tapering glucocorticoid treatment in patients with severe SARS-CoV 2 infection can prevent acute adrenal insufficiency in the geriatric population
Objective and designGlucocorticoids (GCs) have been widely used in symptomatic patients for the treatment of COVID-19. The risk for adrenal...
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Corticosteroids in sepsis and community-acquired pneumonia
Sepsis and septic shock, which are often caused by pneumonia, impact millions of people every year. Despite adequate antibiotic therapy, mortality...
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What we have to know about corticosteroids use during Sars-Cov-2 infection
PurposeGlucocorticoids (GCs), alone or associated to other drugs, were widely used in the management of patients affected by severe acute respiratory...
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Low-dose corticosteroid therapy for cardiogenic shock in adults (COCCA): study protocol for a randomized controlled trial
BackgroundCardiogenic shock (CS) is a life-threatening condition characterized by circulatory insufficiency caused by an acute dysfunction of the...
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Guideline-based management of acute respiratory failure and acute respiratory distress syndrome
Acute respiratory failure (ARF) is defined by acute and progressive hypoxemia caused by various cardiorespiratory or systemic diseases in previously...
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Adrenal insufficiency in liver diseases - pathophysiology and underlying mechanisms
Relative adrenal insufficiency (RAI) is common in critically ill patients with cirrhosis, but it has been also documented in non-critically ill...
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Renaissance of glucocorticoids in critical care in the era of COVID-19: ten urging questions
The 40-year-old experience with glucocorticosteroids (GCs) in the context of severe infections is complex and troublesome. Recently, however, a clear...
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Bivalirudin for cardiopulmonary bypass in a patient with heparin allergy
BackgroundHypersensitivity reactions to heparin are uncommon conditions but pose a serious clinical problem for patients requiring cardiopulmonary...
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The need to monitor emerging issues in etomidate usage: the misuse or abuse potential
Since 2011, the misuse or abuse of etomidate has gradually increased when propofol was designated a controlled drug under the Narcotics Control Act...
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COVID-19 pandemic and adrenals: deep insights and implications in patients with glucocorticoid disorders
PurposeCoronavirus disease-19 (COVID-19) has spread throughout the world. It was initially defined as a potentially severe syndrome affecting the...
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Praktische Empfehlungen zum Screening und Management von Funktionsstörungen der Nebennierenrinde bei einer akuten SARS-CoV-2-Infektion
Diseases of the adrenal cortex require particular attention during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic....
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Vertebral bone quality score for opportunistic osteoporosis screening: a correlation and optimal threshold analysis
PurposeThis study investigated the vertebral bone quality (VBQ) score as a potential tool for opportunistic osteoporosis screening and its...
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Adrenal function and dysfunction in critically ill patients
Critical illnesses are characterized by increased systemic cortisol availability, which is a vital part of the stress response. Relative adrenal...
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Infections and gender: clues for diagnosis of adrenal insufficiency—a case report and a review of the literature
The clinical presentation of adrenal insufficiency, a condition causing adrenal hormone deficiency, is characterised by non-specific symptoms and...
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An Improved Transosseous Pullout Suture Technique for Arthroscopic Repair of a Meniscus Root Tear
ObjectiveThis study aimed to explore the clinical efficiency of an improved transosseous pullout suture technique for arthroscopic repair of a...
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Impact of downstream effects of glucocorticoid receptor dysfunction on organ function in critical illness-associated systemic inflammation
Glucocorticoids (GCs) are stress hormones that regulate developmental and physiological processes and are among the most potent anti-inflammatory...
