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Management Modalities of Aggressive Brown Tumor of the Jaws—a Case Series
Primary hyperparathyroidism is an endocrine disorder occurring due to increased secretion of parathormone resulting in clinical, anatomical, and...
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Brown tumor due to primary hyperparathyroidism in a familial case: a case report
BackgroundPrimary hyperparathyroidism (PHPT) is an uncommon disorder characterised by hypercalcemia with an increased parathyroid hormone level. We...
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Gene Polymorphism Influencing Persistent Bone Resorption in Brown Tumor: A Case Series with Possible Pathogenesis and Potential Therapeutic Approach
Brown tumor represents a terminal stage of bone remodeling process due to an imbalance between osteoclastic and osteoblastic activity. It represents...
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The refractory secondary hyperparathyroidism presenting with retro-orbital brown tumor: a case report
BackgroundTertiary hyperparathyroidism describes the autonomous and excessive secretion of parathyroid hormone (PTH) by the parathyroid glands after...
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Brown tumors: Retrospective analysis of 26 cases
IntroductionBrown tumors are reactive osteolytic lesions caused by hyperparathyroidism. These rare lesions are non-neoplastic processes that result...
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The value of integration of bone scan and targeted SPECT/CT in diagnosis of primary hyperparathyroidism with multiple bone brown tumor
Although parathyroid bone disease is rarely seen nowadays, skeletal manifestation can be the first sign of hyperparathyroidism (HPT) in some clinical...
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An unusual case report: normocalcemic markers and their relationship with multiple sclerosis in primary hyperparathyroidism disease revealed by radiological markers with the diagnosis of brown tumor
BackgroundBrown tumor is a giant cell focal bone lesion associated with hyperparathyroidism and is more common in long bones such as the femur, ribs,...
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Multiple brown tumors: a bone complication due to long-term untreated pseudohypoparathyroidism
Bone lytic lesions are a possible complication of pseudohypoparathyroidism type 1B, in undertreated adult patients. Whole body [18F] F-fluorocholine...
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When parathyroid adenoma meets osteopathia striata, rarest amalgam of bony dysplasia with brown tumors: a case report
BackgroundOsteopathia is a benign entity characterized by linear densities along the diaphysis and metaphysis of the longitudinal axes of the long...
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Widespread presentation of brown tumors mimicking multiple myeloma
Brown tumors or osteitis fibrosa cystica has become a rare presentation of primary hyperparathyroidism in up-to-date clinical practice. Here, we...
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Large Brown Tumour of Mandible with Bleeding as Initial Presentation: A Case Report
Brown Tumour or Osteitis fibrous cystic or Von-Recklinghausen disease of bone is a non-malignant condition due to abnormal metabolism of bones in...
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An update on the secretory functions of brown, white, and beige adipose tissue: Towards therapeutic applications
Adipose tissue, including white adipose tissue (WAT), brown adipose tissue (BAT), and beige adipose tissue, is vital in modulating whole-body energy...
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Brown tumors in nuclear medicine: a systematic review
Brown tumors (BT) are abnormal bone-repair processes and a consequence of hyperparathyroidism. The diagnosis of these lytic lesions in nuclear...
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Predictive value of cyst/tumor volume ratio of pituitary adenoma for tumor cell proliferation
BackgroundMRI has been widely used to predict the preoperative proliferative potential of pituitary adenoma (PA). However, the relationship between...
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Expression of Epidermal Growth Factor Receptor (EGFR) and β-catenin in Colorectal Carcinoma and its Correlation with Tumor Grade and Stage
Colorectal cancer (CRC) is considered the result of the cumulative effect of multiple mutations within the cell that allow it to escape growth...
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A para-aortic malignant melanotic nerve sheath tumor mimicking a gastrointestinal stromal tumor: a rare case report and review of literature
BackgroundMalignant melanotic nerve sheath tumor (MMNST), formerly called melanotic schwannoma, is a rare tumor of neural crest derivation which most...
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Lenvatinib activates anti-tumor immunity by suppressing immunoinhibitory infiltrates in the tumor microenvironment of advanced hepatocellular carcinoma
BackgroundLenvatinib, a multiple receptor tyrosine kinase inhibitor, might exert antitumor effects via tumor immune modulation. However, changes in...
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Perivascular epithelioid cell tumor (PEComa) of the cystic duct
Perivascular epithelioid cell tumors, also known as PEComas, are rare mesenchymal tumors composed mainly of epithelioid cells found in perivascular...
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Severe hypercalcemia and a pelvic brown tumor in an adolescent with primary hyperparathyroidism: a case report
BackgroundPrimary hyperparathyroidism may present in a myriad of manners, varying from an incidental asymptomatic biochemical finding to...
