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Showing 1-20 of 4,403 results
  1. The Role of Branched-chain Amino Acids and Their Metabolism in Cardiovascular Diseases

    Branched-chain amino acids (BCAAs), including leucine, isoleucine, and valine, are essential amino acids for protein synthesis. Recent studies have...

    Zhiyu Li, Yibin Wang, Haipeng Sun in Journal of Cardiovascular Translational Research
    Article 12 January 2024
  2. Association between type 2 diabetes and branched chain amino acids (BCAA); a case-control study

    Background

    Several amino acids and their derivatives have been implicated in insulin resistance (IR) and Type 2 Diabetes Mellitus (T2DM). This...

    Saheb Abbas Torki, Effat Bahadori, ... Maryam Gholamalizadeh in Journal of Diabetes & Metabolic Disorders
    Article 22 July 2023
  3. Branched-chain amino acids in cardiovascular disease

    Research conducted in the past 15 years has yielded crucial insights that are resha** our understanding of the systems physiology of branched-chain...

    Robert W. McGarrah, Phillip J. White in Nature Reviews Cardiology
    Article 05 September 2022
  4. Branched chain amino acids harbor distinct and often opposing effects on health and disease

    Background

    The branched chain amino acids (BCAA) leucine, isoleucine, and valine are essential nutrients that have been associated with diabetes,...

    Christy L. Avery, Annie Green Howard, ... Mariaelisa Graff in Communications Medicine
    Article Open access 28 November 2023
  5. Associations between sarcopenia and circulating branched-chain amino acids: a cross-sectional study over 100,000 participants

    Background

    Emerging evidence suggests that alterations in BCAA metabolism may contribute to the pathogenesis of sarcopenia. However, the relationship...

    HuiMin Liu, Qiang Zhang, ... YanJie Jia in BMC Geriatrics
    Article Open access 21 June 2024
  6. The relationship between the intake of branched-chain and aromatic amino acids and individuals' sleep quality based on body mass index, gender, and age

    Sleep disorder is a relatively common problem that causes chronic conditions such as obesity, diabetes, and cardiovascular diseases. It is believed...

    Sahar Noori, Maryam Nadery, ... Ariyo Movahedi in Journal of Health, Population and Nutrition
    Article Open access 26 May 2023
  7. Correlation between branched-chain amino acids intake and total lymphocyte count in head and neck cancer patients: a cross-sectional study

    Background

    Cellular immunity as reflected by total lymphocyte count (TLC) has been proven to be related to overall survival rate cancer patients....

    Yosua Yan Kristian, Rahmat Cahyanur, ... Wiji Lestari in BMC Nutrition
    Article Open access 14 July 2023
  8. Preoperative administration of branched-chain amino acids reduces postoperative insulin resistance in rats by reducing liver gluconeogenesis

    Background

    Postoperative insulin resistance (PIR) represents an important characteristic of metabolic response following surgical injury. Clinical...

    ** Zhang, Rui Chi, ... Peng Sun in Nutrition & Metabolism
    Article Open access 29 November 2022
  9. Habitual changes in dietary branched-chain amino acids intake are not correlated with exercise-induced glycemia changes in postmenopausal women

    Objective

    To verify whether habitual changes in dietary branched-chain amino acids (BCAA) intake are correlated with glycemic profile improvements...

    Heitor O. Santos, Luana T. Rossato, ... Erick P. de Oliveira in Nutrire
    Article 30 August 2023
  10. Lysophospholipids and branched chain amino acids are associated with aging: a metabolomics-based study of Chinese adults

    Background

    Aging is an inevitable process associated with impairments in multiple organ systems, which increases the risk of comorbidity and...

    Yiming Pan, Pan Liu, ... Lina Ma in European Journal of Medical Research
    Article Open access 02 February 2023
  11. Association between mitochondrial DNA haplogroups J and K, serum branched-chain amino acids and lowered capability for endurance exercise

    Background

    Endurance exercise training promotes the catabolism of branched-chain amino acids (BCAAs) in skeletal muscles. We have previously shown...

    Jukka M. Kiiskilä, Ilmo E. Hassinen, ... Kari Majamaa in BMC Sports Science, Medicine and Rehabilitation
    Article Open access 26 May 2022
  12. Dietary branched-chain amino acids intake, glycemic markers, metabolic profile, and anthropometric features in a community-based sample of overweight and obese adults

    Background

    Existing research provides conflicting evidence regarding the relationship between estimated branched-chain amino acid (BCAA) intake and...

    Ensiye Soleimani, Fariborz Rashnoo, ... Yoones Sadabadi in BMC Endocrine Disorders
    Article Open access 25 September 2023
  13. Branched-chain amino acids supplementation improves liver frailty index in frail compensated cirrhotic patients: a randomized controlled trial

    Background

    Physical frailty is related with morbidity and mortality in patients with cirrhosis. Currently, there is no approved treatment of frailty...

    Sith Siramolpiwat, Nisakorn Limthanetkul, ... Navapan Issariyakulkarn in BMC Gastroenterology
    Article Open access 15 May 2023
  14. Branched-Chain Amino Acid Metabolism in the Failing Heart

    Branched-chain amino acids (BCAAs) are essential amino acids which have critical roles in protein synthesis and energy metabolism in the body. In the...

    Qutuba G. Karwi, Gary D. Lopaschuk in Cardiovascular Drugs and Therapy
    Article 12 February 2022
  15. Effects of serum branched-chain amino acids on nonalcoholic fatty liver disease and subsequent cardiovascular disease

    Background

    To reveal the role of branched-chain amino acids (BCAAs) in the development and progression of nonalcoholic fatty liver disease (NAFLD) and...

    Fei Guo, Rui Chen, ... Wen Hu in Hepatology International
    Article 18 July 2022
  16. Dietary intake of branched-chain amino acids in relation to the risk of breast cancer

    Background

    Given that, studies on the association of dietary intake of branched-chain amino acids (BCAAs) with risk of cancers, especially breast...

    Saeedeh Nouri-Majd, Asma Salari-Moghaddam, ... Ahmad Esmaillzadeh in Breast Cancer
    Article 06 July 2022
  17. Differences in branched-chain amino acid to tyrosine ratio (BTR) among etiologies of chronic liver disease progression compared to healthy adults.

    Background

    The branched-chain amino acids (BCAAs) to tyrosine (Tyr) ratio (BTR) test is used to evaluate the progression of chronic liver disease...

    Masaaki Mino, Akitoshi Sano, ... Tatsuya Kanto in Journal of Gastroenterology
    Article 26 March 2024
  18. Detrimental effects of branched-chain amino acids in glucose tolerance can be attributed to valine induced glucotoxicity in skeletal muscle

    Objective

    Current data regarding the roles of branched-chain amino acids (BCAA) in metabolic health are rather conflicting, as positive and negative...

    Christopher A. Bishop, Tina Machate, ... Karolin Weitkunat in Nutrition & Diabetes
    Article Open access 13 April 2022
  19. Dietary intakes of branched-chain amino acids and plasma lipid profiles among filipino women in Korea: the Filipino Women’s Diet and Health Study (FiLWHEL)

    Background

    The potential role of dietary branched-chain amino acids (BCAA) in metabolic health, including cardiovascular disease and diabetes, is...

    Akinkunmi Paul Okekunle, Hee** Lee, ... Jung Eun Lee in Nutrition Journal
    Article Open access 11 July 2023
  20. Effects of Branched-chain Amino Acids on Nutritional Metabolism and Pharmacoeconomics in Patients with Severe Abdominal Trauma

    Objective

    To observe the influences of branched-chain amino acids (BCAAs) on nutrition metabolism and prognosis of patients with severe abdominal...

    Bin Xu, Di Wu, ... **ao Chen in Current Medical Science
    Article 15 October 2021
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