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Unlocking the potential: phenylboronic acid as a nuclear-targeting boron agent for neutron capture therapy
It has been proposed that boron neutron capture therapy (BNCT) holds promise as a treatment modality for melanoma. However, the effectiveness of...
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Profile of miRNAs in small extracellular vesicles released from glioblastoma cells treated by boron neutron capture therapy
PurposeBoron neutron capture therapy (BNCT) is a tumor cell-selective particle-radiation therapy. In BNCT, administered p -boronophenylalanine (BPA)...
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Salvage boron neutron capture therapy for pediatric patients with recurrent diffuse midline glioma
PurposePediatric diffuse malignant glioma located in the brainstem was officially named “diffuse midline glioma” (DMG) by the World Health...
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First optical observation of 10B-neutron capture reactions using a boron-added liquid scintillator for quality assurance in boron neutron capture therapy
10 B-neutron capture was observed optically using a boron-added liquid scintillator. Trimethyl borate was dissolved in a commercially available liquid...
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Boron neutron capture therapy using dodecaborated albumin conjugates with maleimide is effective in a rat glioma model
Introduction Boron neutron capture therapy (BNCT) is a biologically targeted, cell-selective particle irradiation therapy that utilizes the nuclear...
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Impact of gadolinium concentration and cell oxygen levels on radiobiological characteristics of gadolinium neutron capture therapy technique in brain tumor treatment
Neutron capture therapy (NCT) with various concentrations of gadolinium ( 157 Gd) is one of the treatment modalities for glioblastoma (GBM) tumors....
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Analyzing spatial distribution between 18F-fluorodeoxyglucose and 18F-boronophenylalanine positron emission tomography to investigate selection indicators for boron neutron capture therapy
Background18 F-FDG PET is often utilized to determine BNCT selection due to the limited availability of 18 F-BPA PET, which is performed by...
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Boron neutron capture therapy for malignant brain tumors
BackgroundBoron neutron capture therapy (BNCT) is tumor-selective particle radiation therapy that depends on the nuclear capture and fission...
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Boron neutron capture therapy: moving towards targeted therapy for locally recurrent head and neck squamous cell carcinoma
Locally recurrent head and neck squamous cell carcinoma (HNSCC) is often unresectable, and a repeat course of radiotherapy is associated with...
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A bis-boron boramino acid PET tracer for brain tumor diagnosis
PurposeBoramino acids are a class of amino acid biomimics that replace the carboxylate group with trifluoroborate and can achieve the 18 F-labeled...
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KSNM60 in Non-thyroidal Radionuclide Therapy: Lea** into the Future
This year, the Korean Society of Nuclear Medicine (KSNM) is celebrating its 60th anniversary. Treatment, as well as diagnosis, has played a very...
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Similar T/N ratio between 18F-FBPA diagnostic and BPA therapeutic dosages for boron neutron capture therapy in orthotropic tongue cancer model
ObjectiveThe tumor-to-normal tissue (T/N) boron ratio is determined in a patient prior to boron neutron capture therapy (BNCT) using 4-borono-2- 18 F-fluoro-...
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Boron neutron capture therapy (BNCT): a unique role in radiotherapy with a view to entering the accelerator-based BNCT era
Boron neutron capture therapy (BNCT) has a unique property of tumor-cell-selective heavy-particle irradiation. BNCT can form large dose gradients...
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Proton therapy for intracranial meningioma: a single-institution retrospective analysis of efficacy, survival and toxicity outcomes
PurposeTo report the outcomes of a large series of intracranial meningiomas (IMs) submitted to proton therapy (PT) with curative intent.
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Cellular uptake evaluation of pentagamaboronon-0 (PGB-0) for boron neutron capture therapy (BNCT) against breast cancer cells
Pentagamaboronon-0 (PGB-0), a curcumin analog compound, has been synthesized as a candidate of boron-carrier pharmaceutical (BCP) for boron neutron...
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The use of radiosensitizing agents in the therapy of glioblastoma multiforme—a comprehensive review
BackgroundGlioblastoma is the most common malignant brain tumor in human adults. Despite several improvements in resective as well as adjuvant...
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Influence of field-of-view and section thickness of diagnostic imaging on thermal neutron flux estimation in dose-planning for boron neutron capture therapy
Radiation treatment planning for boron neutron capture therapy (BNCT) often uses computed tomography (CT) images reconstructed utilizing various...
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Larger 18F-fluoroboronotyrosine (FBY) active volume beyond MRI contrast enhancement in diffuse gliomas than in circumscribed brain tumors
BackgroundTo investigate the relationship between 18 F-fluoroboronotyrosine (FBY) positron emission tomography (PET)- and magnetic resonance imaging...
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SlicerPIT: software development and implementation for planning and image-guided therapy in photoimmunotherapy
BackgroundPhotoimmunotherapy is a treatment modality that induces targeted cell death by binding a molecular-targeted drug activated by infrared...
