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Biological age is superior to chronological age in predicting hospital mortality of the critically ill
Biological age is increasingly recognized as being more accurate than chronological age in determining chronic health outcomes. This study assessed...
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Clarifying the biological and statistical assumptions of cross-sectional biological age predictors: an elaborate illustration using synthetic and real data
BackgroundThere is divergence in the rate at which people age. The concept of biological age is postulated to capture this variability, and hence to...
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A miRNA-based epigenetic molecular clock for biological skin-age prediction
Skin aging is one of the visible characteristics of the aging process in humans. In recent years, different biological clocks have been generated...
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The AccelerAge framework: a new statistical approach to predict biological age based on time-to-event data
Aging is a multifaceted and intricate physiological process characterized by a gradual decline in functional capacity, leading to increased...
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Signatures of epigenetic, biological and mitotic age acceleration and telomere shortening are associated with arsenic-induced skin lesions
Chronic arsenic exposure is a global health hazard significantly associated with the development of deleterious cutaneous changes and increased...
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The effect of polyphenols on DNA methylation-assessed biological age attenuation: the DIRECT PLUS randomized controlled trial
BackgroundEpigenetic age is an estimator of biological age based on DNA methylation; its discrepancy from chronologic age warrants further...
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Effects of Age on the Biological Properties of Cryopreserved Adipose-Derived Stem Cells and ASC-Enriched Fat Grafts
BackgroundDonor age is an important factor affecting the biological characteristics of human adipose-derived stem cells. The aim of this study was to...
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HOMA-IR is positively correlated with biological age and advanced aging in the US adult population
BackgroundInsulin resistance (IR) had been reported to be associated with age; however, few studies have explored the association between IR and...
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Biological Aging in People Living with HIV on Successful Antiretroviral Therapy: Do They Age Faster?
Purpose of ReviewIn the absence of a prophylactic/therapeutic vaccine or cure, the most amazing achievement in the battle against HIV was the...
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Determination of Biological Age: Geriatric Assessment vs Biological Biomarkers
Purpose of ReviewBiological age is the concept of using biophysiological measures to more accurately determine an individual’s age-related risk of...
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Promoting health and productivity among ageing workers: a longitudinal study on work ability, biological and cognitive age in modern workplaces (PROAGEING study)
BackgroundLarge changes in ageing population and in retirement age are increasing the number of older people in the workforce, raising many...
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Algorithm for Reducing Overall Biological Detriment Caused by PET/CT: an Age-Based Study
PurposeThis study is to use a simple algorithm based on patient’s age to reduce the overall biological detriment associated with PET/CT.
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Biological Age Mediates the Effects of Perceived Neighborhood Problems on Heart Failure Risk Among Black Persons
ObjectiveWe assessed whether biological age, measured by the epigenetic clock GrimAge, mediates the association of objective and subjective...
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Re-examination of successful agers with lower biological than chronological age still after a 20-year follow-up period
BackgroundSuccessful ageing is the term often used for depicting exceptional ageing but a uniform definition is lacking. The aim was to re-examine...
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Imaging analysis of the biological parameters of the lens in patients with cortical age-related cataracts using ultrasound biomicroscopy
BackgroundThe spatial position of the lens in patients with cortical age-related cataract (CARC) is unclear. We investigated a basis for the...
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Relative age, biological maturation, body composition, and physical performance in under-16 academy soccer players: differences and associations among early and late born athletes
PurposeTo examine the differences in body composition and physical performance in academy under-16 (U16) soccer players, born in the first (i.e.,...
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Biological Age Estimation Based on the Spectral Analysis of the Bioelectrical Activity of the Human Brain
AbstractThis research offers a method of estimating human biological age based on the spectral analysis of the bioelectric activity of the brain for...
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Effect of Diet, Exercise, or Both on Biological Age and Healthy Aging in Older Adults with Obesity: Secondary Analysis of a Randomized Controlled Trial
ObjectivesTo determine the effect of diet, exercise, and diet-exercise in combination on measures of biological age.
DesignSecondary analysis of a...
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Growth of nonexudative macular neovascularization in age-related macular degeneration: an indicator of biological lesion activity
PurposeTo investigate the growth of nonexudative macular neovascularization (MNV) in age-related macular degeneration (AMD) using swept-source...
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Immune age and biological age as determinants of vaccine responsiveness among elderly populations: the Human Immunomics Initiative research program
The Human Immunomics Initiative (HII), a joint project between the Harvard T.H. Chan School of Public Health and the Human Vaccines Project (HVP),...