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Do patients referred to emergency departments after being assessed in primary care differ from other ED patients? Retrospective analysis of a random sample from two German metropolitan EDs
BackgroundTo assess differences between patients referred to emergency departments by a primary care physician (PCP) and those presenting directly...
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Enriching limited information on rare diseases from heterogeneous networks for drug repositioning
BackgroundThe historical data of rare disease is very scarce in reality, so how to perform drug repositioning for the rare disease is a great...
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Self-referred walk-in patients in the emergency department – who and why? Consultation determinants in a multicenter study of respiratory patients in Berlin, Germany
BackgroundEmergency department (ED) consultations are on the rise, and frequently consultations by non-urgent patients have been held accountable....
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Yoga is effective for treating chronic pain in veterans with Gulf War Illness at long-term follow-up
BackgroundClinical Practice Guidelines for Gulf War Illness (GWI) recommend integrative health approaches such as yoga for relief from symptoms, yet...
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Addressing non-response data for standardized post-acute functional items
BackgroundThe post-acute patient standardized functional items (Section GG) include non-response options such as refuse, not attempt and not...
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Community ambulation in older adults and people with OA – a model verification using Canadian Longitudinal Study on Aging (CLSA) data
BackgroundThere are health and well-being benefits of community ambulation; however, many older adults do not regularly walk outside of their home....
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Inference following multiple imputation for generalized additive models: an investigation of the median p-value rule with applications to the Pulmonary Hypertension Association Registry and Colorado COVID-19 hospitalization data
BackgroundMissing data prove troublesome in data analysis; at best they reduce a study’s statistical power and at worst they induce bias in parameter...
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Predictive Validity of Different Walking Measures to Identify the Incident Long-Term Care Needs in Older Adults
ObjectivesA comfortable walking speed is a suitable measurement of functional status in older adults. In addition to assessing their comfortable...
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Wearable technology interventions in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death and is associated with multiple medical and psychological...
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Exploring potential circRNA biomarkers for cancers based on double-line heterogeneous graph representation learning
BackgroundCompared with the time-consuming and labor-intensive for biological validation in vitro or in vivo, the computational models can provide...
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Reduced Pain and Improved Function Following Short-Term Use of Noninvasive BioWave High Frequency Peripheral Nerve Stimulation for Pain Management
IntroductionThe peripheral nervous system is an increasingly popular target for chronic pain treatment modalities. Noninvasive neuromodulation has...
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Systematic review and network meta-analysis of robot-assisted gait training on lower limb function in patients with cerebral palsy
ObjectiveThis study aimed to evaluate the effectiveness of robot-assisted gait training (RAGT) in treating lower extremity function in patients with...
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Exploring the link between walking and lung cancer risk: a two-stage Mendelian randomization analysis
BackgroundPrevious observational research showed a potential link between physical activities such as walking and the risk of lung cancer. However,...
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Daily socket comfort in transtibial amputee with a vacuum-assisted suspension system: study protocol of a randomized, multicenter, double-blind multiple N-of-1 trial
BackgroundThe main aim of this paper is to present the feasibility of rigorously designed multiple N-of-1 design in prosthetics research. While...
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MetfOrmin BenefIts Lower Extremities with Intermittent Claudication (MOBILE IC): randomized clinical trial protocol
BackgroundPeripheral artery disease (PAD) affects over 230 million people worldwide and is due to systemic atherosclerosis with etiology linked to...
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Investigating sources of non-response bias in a population-based seroprevalence study of vaccine-preventable diseases in the Netherlands
BackgroundPIENTER 3 (P3), conducted in 2016/17, is the most recent of three nationwide serological surveys in the Netherlands. The surveys aim to...
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Spatial-temporal Bayesian accelerated failure time models for survival endpoints with applications to prostate cancer registry data
Prostate cancer is the most common cancer after non-melanoma skin cancer and the second leading cause of cancer deaths in US men. Its incidence and...
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Application of machine learning to predict transport modes from GPS, accelerometer, and heart rate data
BackgroundThere has been an increased focus on active transport, but the measurement of active transport is still difficult and error-prone. Sensor...
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Persisting neuroendocrine abnormalities and their association with physical impairment 5 years after critical illness
BackgroundCritical illness is hallmarked by neuroendocrine alterations throughout ICU stay. We investigated whether the neuroendocrine axes recover...
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Association of greenspaces exposure with cardiometabolic risk factors: a systematic review and meta-analysis
BackgroundCardiometabolic conditions are major contributors to the global burden of disease. An emerging body of evidence has associated access to...
