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Case of acute promyelocytic leukemia with basophilic differentiation and an ETV6 mutation
The translocation between chromosomes 15 and 17 t(15;17) at the promyelocytic leukemia (PML) and retinoic acid receptor alpha (RARA) is thought to be...
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Diagnosis of Adenoid Cystic Carcinoma with Striking Tubular Hypereosinophilia by MYB and EWSR1 Breakapart Fluorescence In Situ Hybridization
BackgroundAdenoid cystic carcinoma (AdCC), associated with MYB/MYBL1 gene rearrangements, shows epithelial and basaloid myoepithelial cells arranged...
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Ocular Crystal-Storing Histiocytosis with Co-existing MALT Lymphoma—A Rare Case with Cytologic and Heretofore Not Reported Findings on Frozen Section
BackgroundCrystal-storing histiocytosis (CSH) is a rare disorder which most commonly occurs in the setting of concurrent lymphoproliferative disease....
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Myeloid sarcoma with RBM15::MRTFA (MKL1) mimicking vascular neoplasm
Extramedullary involvement of acute myeloid leukemia (AML), aka myeloid sarcoma, is a rare phenomenon in acute megakaryoblastic leukemia with RBM15::...
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Microsecretory adenocarcinoma of the hard palate: a case report and literature review
Microsecretory adenocarcinoma (MSA) is a new type of salivary gland neoplasm identified in the 2022 World Health Organization Classification of Head...
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Pericardial malignant mesothelioma diagnosed in a dog by immunocytochemistry of the pericardial fluid: a case report
BackgroundPericardial effusions are one of the most common cardiac diseases in dogs. Common causes of haemorrhagic pericardial effusions include...
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A rare case of ocular and testicular T-cell lymphoma in a hermaphrodite koi carp (Cyprinus carpio Linnaeus 1758): clinical, histopathological, and immunohistochemical study
BackgroundLymphatic neoplasia may occur in various types, such as lymphoma, lymphosarcoma, lympholeukemia, and plasmacytoid leukemia. Lymphoma,...
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True Oncocytic Acinic Cell Carcinoma: A Case Image
A 67-year-old female with a history of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) presented with right sided otalgia and a 2-3...
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A cytodiagnosis of adenoid cystic carcinoma of the tracheobronchial tree through a systematic clinical case comparison and analysis
BackgroundPrimary adenoid cystic carcinoma (AdCC) of the tracheobronchial tree is very rare with a high risk for recurrence and metastasis. The...
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Polycystic ovary rat model exposure to 150 kHz intermediate frequency: hypothalamic-pituitary-ovarian axis at the receptor, cellular, tissue, and hormone levels
IntroductionThe hypothalamic-pituitary-ovarian (HPO) axis is the principal regulator of the reproductive system. The neurons in the arcuate nucleus...
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mTOR eosinophilic renal cell carcinoma: a distinctive tumor characterized by mTOR mutation, loss of chromosome 1, cathepsin-K expression, and response to target therapy
In the spectrum of oncocytic renal neoplasms, a subset of tumors with high-grade-appearing histologic features harboring pathogenic mutations in...
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Top 10 Histological Mimics of Neuroendocrine Carcinoma You Should Not Miss in the Head and Neck
BackgroundThe spectrum of neuroendocrine neoplasia (NEN) of the head and neck region is wide-ranging and diverse, including a variety of diagnoses...
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Acute trypanosomiasis in a dog from Brazil: a case report study
We report a natural case of Trypanosoma cruzi infection in a dog from Brazil that died after presenting apathy, anorexia, diarrhea, mucous pallor,...
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Top 10 Basaloid Neoplasms of the Sinonasal Tract
BackgroundBasaloid neoplasms of the sinonasal tract represent a significant group of tumors with histological overlap but often with different...
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Thyroxine restores hippocampal neurogenesis and synaptogenesis in a male rat model of carbimazole-induced hypothyroidism: a histological study
BackgroundAdult-onset hypothyroidism has a deleterious effect on hippocampal cognitive and memory functions. This study was performed to evaluate the...
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SMARCB1-deficient sinonasal adenocarcinoma: a rare variant of SWI/SNF-deficient malignancy often misclassified as high-grade non-intestinal-type sinonasal adenocarcinoma or myoepithelial carcinoma
SMARCB1-deficient sinonasal adenocarcinoma is a rare variant of SWI/SNF-deficient malignancies with SMARCB1 loss and adenocarcinoma features. More...
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Hidradenoma of Pinna -Report of a Rare Case at a Rare Site
There are various reports of hidradenoma of cartilaginous part of external auricular canal (ear), but the documented evidence of occurrence of...
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De novo neuroendocrine transdifferentiation in primary prostate cancer–a phenotype associated with advanced clinico-pathologic features and aggressive outcome
Neuroendocrine transdifferentiation of high-grade prostate cancer (PCA-NT) comprises a morphologic and immunophenotypic transition from conventional...
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Bronchial salivary gland–type intraductal carcinoma with KIAA1217::RET gene fusion composed of intercalated and oncocytic components
Salivary gland–type intraductal carcinoma (IC) is a rare malignant salivary gland neoplasm. Primary salivary gland–type IC has never been described...
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Malakoplakia Involving the Maxilla: A Case Report and a Review of the Literature
Malakoplakia is a rare inflammatory disorder which typically occurs in immunocompromised patients secondary to impaired bactericidal activity of...
