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Cross-sectional analysis characterizing the use of rank preserving structural failure time in oncology studies: changes to hazard ratio and frequency of inappropriate use
BackgroundRank preserving structural failure time (RPSFT) is a statistical method to correct or adjust for crossover in clinical trials, by...
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An Investigation into the Relationship Between Choice of Model Structure and How to Adjust for Subsequent Therapies Using a Case Study in Oncology
BackgroundA common challenge in health technology assessments (HTAs) of cancer treatments is how subsequent therapy use within the trial follow-up...
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Fall history in older adults impacts acceleration profiles after a near collision with a moving pedestrian hazard
BackgroundEnvironmental hazards (e.g., pedestrian traffic) cause falls and testing environment impacts gait in older adults. However, most fall risk...
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Is waist-calf circumference ratio associated with frailty in older adults? Findings from a cohort study
BackgroundThe waist-calf circumference ratio (WCR) has been suggested as a potential indicator of visceral adiposity. Nevertheless, the relationship...
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Opioid Initiation and the Hazard of Falls or Fractures Among Older Adults with Varying Levels of Central Nervous System Depressant Burden
BackgroundCo-prescription of opioids with other central nervous system (CNS) depressants is common but the combination may increase the risk for...
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Dietary sodium to potassium ratio is an independent predictor of cardiovascular events: a longitudinal follow-up study
BackgroundThe current prospective cohort study aimed to explore the potential associations between dietary sodium (Na), potassium (K), and...
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Prevalence and associated factors of teenage childbearing among Ethiopian women using semi-parametric and parametric proportional hazard and accelerated failure time models
BackgroundTeenage childbearing is a common issue for young people’s sexual and reproductive health in the world, particularly in low-income...
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The effect of smoking on latent hazard classes of metabolic syndrome using latent class causal analysis method in the Iranian population
BackgroundThe prevalence of metabolic syndrome is increasing worldwide. Clinical guidelines consider metabolic syndrome as an all or none medical...
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Association of body mass index and waist-to-height ratio with outcomes in ischemic stroke: results from the Third China National Stroke Registry
Background and purposeConflicting reports of obesity paradox have led to confusion about weight management strategies for post-stroke patients. The...
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The prognostic value of lymph node to primary tumor standardized uptake value ratio in cancer patients: a meta-analysis
ObjectiveThe lymph node to primary tumor standardized uptake value ratio (NTR) is an innovative parameter derived from positron emission...
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Trends in Burdens of Disease by Transmission Source (USA, 2005–2020) and Hazard Identification for Foods: Focus on Milkborne Disease
BackgroundRobust solutions to global, national, and regional burdens of communicable and non-communicable diseases, particularly related to diet,...
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Association between input/weight ratio and acute kidney injury in obese critical ill patients: a propensity analysis of multicenter clinical databases
Rehydration volume may be underestimated in obese critically ill patients, which can lead to acute kidney injury (AKI). This study aimed to...
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High neutrophil-to-lymphocyte ratio is associated with cancer therapy-related cardiovascular toxicity in high-risk cancer patients under immune checkpoint inhibitor therapy
BackgroundCancer therapy-related cardiovascular toxicity (CTR-CVT) from immune checkpoint inhibitor (ICI) therapy is still incompletely...
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Prognostic impact of resting full-cycle ratio and diastolic non-hyperemic pressure ratios in patients with deferred revascularization
BackgroundNon-hyperemic pressure ratios (NHPRs) like resting full-cycle ratio (RFR), diastolic pressure ratio during entire diastole (dPR[entire])...
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Association between non-high-density lipoprotein to high-density lipoprotein ratio and reversion to normoglycemia in people with impaired fasting glucose: a 5-year retrospective cohort study
ObjectiveThe relationship between the non-high-density lipoprotein to high-density lipoprotein ratio (non-HDL-c/HDL-c ratio) and changes in glycemic...
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Elevated non-HDL-C/HDL-C ratio increases the 1-year risk of recurrent stroke in older patients with non-disabling ischemic cerebrovascular events: results from the **’an Stroke Registry Study of China
BackgroundFew studies have explored the prognostic role of nontraditional lipid-related indicators in non-disabling ischemic cerebrovascular events...
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J-shaped association of free triiodothyronine to free thyroxine ratio with 5-year mortality among patients with chronic kidney disease: a prospective cohort study
PurposeTo investigate the association of free triiodothyronine to free thyroxine (FT3/FT4) ratio with 5-year mortality in patients with chronic...
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The association between creatinine to body weight ratio and the risk of progression to diabetes from pre-diabetes: a 5-year cohort study in Chinese adults
ObjectiveEvidence on the association between the creatinine to body weight (Cre/BW) ratio and the risk of pre-diabetes to diabetes development...
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J-shaped relationship between stress hyperglycemia ratio and 90-day and 180-day mortality in patients with a first diagnosis of acute myocardial infarction: analysis of the MIMIC-IV database
AimsThe Stress Hyperglycemia Ratio (SHR) potently predicts adverse outcomes in patients with cardiovascular and cerebrovascular diseases. However,...
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Association of neutrophil-lymphocyte ratio with all-cause and cardiovascular mortality in US adults with diabetes and prediabetes: a prospective cohort study
BackgroundThe neutrophil-lymphocyte ratio (NLR) is a novel hematological parameter to assess systemic inflammation. Prior investigations have...
