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A secondary abdominal aorta-duodenal fistula accompanied with acquired Immune Deficiency Syndrome presented with recurrent sepsis: a case report
BackgroundAbdominal aorta-duodenal fistulas are rare abnormal communications between the abdominal aorta and duodenum. Secondary abdominal...
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Clinical characteristics and prognostic factors of 60 patients with acquired immune deficiency syndrome combined with Cryptococcus neoformans
ObjectiveCryptococcal meningitis (CM) threatens people’s health and is the main cause of opportunistic fungus-related death in acquired immune...
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Cidofovir for treating complicated monkeypox in a man with acquired immune deficiency syndrome
In July 23, the World Health Organization (WHO) declared monkeypox (MPX) a global health emergency of international concern given its rapid spread....
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Acquired immune thrombotic thrombocytopenic purpura (TTP) associated with inactivated COVID-19 vaccine CoronaVac
Corona virus disease 2019 (COVID-19) due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has affected the whole world....
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Colitis and Intestinal Granulomas in Acquired Immunodeficiency Syndrome
Granulomas consist of focal collections of immune cells that forms as a result of chronic inflammation. They can be formed in different organs and...
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The impact of acquired coagulation factor XIII deficiency in traumatic bleeding and wound healing
Factor XIII (FXIII) is a protein involved in blood clot stabilisation which also plays an important role in processes including trauma, wound...
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ICU-acquired infections in immunocompromised patients
Immunocompromised patients account for an increasing proportion of the typical intensive care unit (ICU) case-mix. Because of the increased...
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Retrospectively diagnosed autoimmune VWF deficiency in a patient with repeated hemorrhagic events after two common colds
Autoimmune von Willebrand factor (VWF) deficiency (AiVWFD) caused by anti-VWF autoantibodies is a rare bleeding disorder, whereas “non-immune”...
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HLA analysis of immune checkpoint inhibitor-induced and idiopathic isolated ACTH deficiency
PurposeIsolated adrenocorticotropic hormone deficiency is a rare disease; however, since immune check point inhibitors (ICIs) have become widely...
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Idiopathic isolated adrenocorticotropic hormone deficiency: a systematic review of a heterogeneous and underreported disease
Isolated adrenocorticotropic hormone deficiency (IAD) is considered to be a rare disease. Due to the nonspecific clinical presentation, precise data...
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Acquired thyroid-stimulating hormone, luteinizing hormone, and follicle-stimulating hormone deficiencies with circulating anti-glycoprotein hormones alpha chain-positive cell antibodies
BackgroundA patient with systemic lupus erythematosus (SLE) suffered from acquired thyroid-stimulating hormone (TSH), luteinizing hormone (LH), and...
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GATA2 Deficiency: Predisposition to Myeloid Malignancy and Hematopoietic Cell Transplantation
Purpose of ReviewGATA2 deficiency is a haploinsufficiency syndrome associated with a wide spectrum of disease, including severe monocytopenia and B...
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Secondary immune-mediated thrombotic thrombocytopenic purpura in idiopathic inflammatory myopathy: a case-based review
Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is a potentially fatal acquired thrombotic microangiopathy syndrome that frequently...
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Newly diagnosed type 1 diabetes mellitus in a human immunodeficiency virus-infected patient with antiretroviral therapy-induced immune reconstitution inflammatory syndrome: a case report
BackgroundDiabetes that develops in human immunodeficiency virus (HIV)-infected patients who receive antiretroviral therapy (ART) is usually type 2...
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A comparative study of multimodal magnetic resonance in the differential diagnosis of acquired immune deficiency syndrome related primary central nervous system lymphoma and infection
BackgroundPatients with acquired immune deficiency syndrome (AIDS) often suffer from opportunistic infections and related primary central nervous...
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Understanding COVID-19 in children: immune determinants and post-infection conditions
AbstractCoronavirus disease 2019 in children presents with milder clinical manifestations than in adults. On the other hand, the presence of a wide...
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ASGR1 deficiency diverts lipids toward adipose tissue but results in liver damage during obesity
BackgroundAsialoglycoprotein receptor 1 (ASGR1), primarily expressed on hepatocytes, promotes the clearance and the degradation of glycoproteins,...
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Atypical presentations of primary acquired hypothyroidism – a case series
Primary acquired hypothyroidism in children manifests with a myriad of clinical presentations. Clinical features can be insidious in nature, often...
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Glioma arising in the setting of mismatch repair deficiency—rare or are we missing it?
Germline mutations in mismatch repair (MMR) genes (MLH1, MSH2, MSH6, PMS2) can be mono-allelic or biallelic, resulting in a Lynch syndrome (LS) or...
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“De novo replication repair deficient glioblastoma, IDH-wildtype” is a distinct glioblastoma subtype in adults that may benefit from immune checkpoint blockade
Glioblastoma is a clinically and molecularly heterogeneous disease, and new predictive biomarkers are needed to identify those patients most likely...